KEGG   ORTHOLOGY: K12323
Entry
K12323                      KO                                     

Symbol
ANPRA, NPR1
Name
atrial natriuretic peptide receptor A [EC:4.6.1.2]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04270  Vascular smooth muscle contraction
map04714  Thermogenesis
map04921  Oxytocin signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04924  Renin secretion
map04925  Aldosterone synthesis and secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
   04022 cGMP-PKG signaling pathway
    K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
   04921 Oxytocin signaling pathway
    K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
   04924 Renin secretion
    K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
   04925 Aldosterone synthesis and secretion
    K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
  09159 Environmental adaptation
   04714 Thermogenesis
    K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.2  guanylate cyclase
     K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  RGC family [OT]
   K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A
Other DBs
RN: R00434
GO: 0004383
Genes
HSA: 4881(NPR1)
PTR: 457329(NPR1)
PPS: 100983770(NPR1)
GGO: 101131617(NPR1)
PON: 100442459(NPR1)
NLE: 100601694(NPR1)
MCC: 715598(NPR1)
MCF: 102143449(NPR1)
CSAB: 103223952(NPR1)
CATY: 105593468(NPR1)
PANU: 101013269(NPR1)
RRO: 104663522(NPR1)
RBB: 108518838(NPR1)
PTEH: 111543699(NPR1)
CJC: 100396371(NPR1)
SBQ: 101044584(NPR1)
MMUR: 105885913(NPR1)
MMU: 18160(Npr1)
MCAL: 110291324(Npr1)
MPAH: 110320830(Npr1)
RNO: 24603(Npr1)
MCOC: 116093218(Npr1)
MUN: 110554242(Npr1)
CGE: 100752423(Npr1)
PLEU: 114707921(Npr1)
NGI: 103751781(Npr1)
HGL: 101714641(Npr1)
CCAN: 109688055(Npr1)
OCU: 100343663(NPR1)
CFA: 490455(NPR1)
VVP: 112918863(NPR1)
VLG: 121491576(NPR1)
AML: 100472771(NPR1)
UAH: 113245333(NPR1)
ORO: 101384059(NPR1)
ELK: 111138909
MPUF: 101689229(NPR1)
EJU: 114198680(NPR1)
MLX: 118013821(NPR1)
FCA: 101080682(NPR1)
PPAD: 109256259(NPR1)
AJU: 106987270(NPR1)
HHV: 120221529(NPR1)
BTA: 533048(NPR1)
BOM: 102279810(NPR1)
BIU: 109554550(NPR1)
BBUB: 102407343(NPR1)
CHX: 102186447(NPR1)
OAS: 101123436(NPR1)
ODA: 120855776(NPR1)
SSC: 100153508(NPR1)
CBAI: 105068204(NPR1)
CDK: 105089423(NPR1)
BACU: 103006879(NPR1)
LVE: 103088382(NPR1)
OOR: 101288628(NPR1)
DLE: 111167040(NPR1)
PCAD: 102982050(NPR1)
ECB: 100061959(NPR1)
EPZ: 103566725(NPR1)
EAI: 106846257(NPR1)
MYB: 102249825(NPR1)
MMYO: 118673296(NPR1)
MNA: 107543755(NPR1)
HAI: 109373524(NPR1)
DRO: 112315464(NPR1)
SHON: 118990211(NPR1)
AJM: 119061784(NPR1)
MMF: 118637319(NPR1)
PGIG: 120592268(NPR1)
RAY: 107509091(NPR1)
MJV: 108397230(NPR1)
TOD: 119235862(NPR1)
LAV: 100671961(NPR1)
TMU: 101346019
MDO: 100019736(NPR1)
SHR: 100921526(NPR1)
PCW: 110211999(NPR1)
OAA: 103166385(NPR1)
GGA: 107055115
PCOC: 116239573(NPR1)
TGU: 100219844(NPR1)
PMOA: 120501862(NPR1)
PHI: 106628815(NPR1)
PMAJ: 107214622(NPR1)
NNI: 104018278(NPR1)
ASN: 102373414(NPR1)
AMJ: 106736703(NPR1)
CPOO: 109324727(NPR1)
GGN: 109300818(NPR1)
CMY: 102945517(NPR1)
CPIC: 101943791(NPR1)
TST: 117888877(NPR1)
CABI: 116832717(NPR1)
ZVI: 118075827(NPR1)
XLA: 397794(npr1.S) 399070(npr1.L)
XTR: 100492092(npr1)
DRE: 555911(npr1b) 560653(npr1a)
IPU: 108273278(npr1) 108273580
LCO: 104935872 104938056(npr1)
CGOB: 115020956
ELY: 117265782
PLEP: 121945845
SLUC: 116064632
ECRA: 117945904
PFLV: 114557964(npr1)
GAT: 120810561
ONL: 100692491 100695733(npr1)
OAU: 116320795(npr1a) 116327706(npr1b)
OLA: 100125799(olgc2)
OML: 112136586
XHE: 116717142
CTUL: 119780918
NFU: 107379009
ALIM: 106532490
AOCE: 111575228(npr1)
CSEM: 103393749(npr1)
SDU: 111223303(npr1) 111234078
SLAL: 111659062(npr1) 111669801
XGL: 120784334 120786600(npr1a)
HCQ: 109512127(npr1)
BPEC: 110157880(npr1)
AANG: 118225106(npr1b) 118234391
LOC: 102686384(npr1)
PSPA: 121306985
CIN: 100177156
SKO: 100372572
DME: Dmel_CG31183(CG31183) Dmel_CG3216(CG3216)
DSI: Dsimw501_GD20320(Dsim_GD20320) Dsimw501_GD25238(Dsim_GD25238)
MDE: 101888358
LCQ: 111687243
CPII: 120422359
DQU: 106752087
PCF: 106784163
CSOL: 105362022
CCIN: 107266322
TCA: 100141543(GLEAN_04747) 664507
ATD: 109594333
APLN: 108733837
PPYR: 116165909
OTU: 111425566
BMOR: 692412(Gcy)
BMAN: 114239257
PMAC: 106721157
PRAP: 111000259
HAW: 110371350
TNL: 113499262
PXY: 105389255
API: 100167260
BTAB: 109044685
CLEC: 106670312
ZNE: 110827775
FCD: 110858197
HAZT: 108675882
TUT: 107363722
CSCU: 111621704
CEL: CELE_T01A4.1(gcy-28) CELE_W03F11.2(gcy-17)
CBR: CBG14865(Cbr-gcy-28)
BMY: BM_BM5449(Bma-gcy-28)
TSP: Tsp_10381
PCAN: 112571473
MYI: 110464603
OBI: 106867807
LAK: 106166491
AQU: 100636320
 » show all
Reference
PMID:2569967
  Authors
Lowe DG, Chang MS, Hellmiss R, Chen E, Singh S, Garbers DL, Goeddel DV
  Title
Human atrial natriuretic peptide receptor defines a new paradigm for second messenger signal transduction.
  Journal
EMBO J 8:1377-84 (1989)
DOI:10.1002/j.1460-2075.1989.tb03518.x
  Sequence
[hsa:4881]

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