KEGG   ORTHOLOGY: K12470
Entry
K12470                      KO                                     
Symbol
SH3KBP1, CIN85
Name
SH3 domain-containing kinase-binding protein 1
Pathway
map04144  Endocytosis
Disease
H00085  Agammaglobulinemias
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K12470  SH3KBP1, CIN85; SH3 domain-containing kinase-binding protein 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12470  SH3KBP1, CIN85; SH3 domain-containing kinase-binding protein 1
Membrane trafficking [BR:ko04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    K12470  SH3KBP1, CIN85; SH3 domain-containing kinase-binding protein 1
 Others
  Actin-binding proteins
   Nucleation-promoting factors (NPFs)
    K12470  SH3KBP1, CIN85; SH3 domain-containing kinase-binding protein 1
Genes
HSA: 30011(SH3KBP1)
PTR: 465527
PPS: 100985113(SH3KBP1)
PON: 100450340(SH3KBP1)
NLE: 100591281(SH3KBP1)
MCC: 694764(SH3KBP1)
MCF: 102127625(SH3KBP1)
CSAB: 103231684(SH3KBP1)
CATY: 105574643(SH3KBP1)
PANU: 101022676(SH3KBP1)
TGE: 112615501(SH3KBP1)
RRO: 104682409(SH3KBP1)
TFN: 117077359(SH3KBP1)
PTEH: 111531657
CJC: 100409963(SH3KBP1)
SBQ: 101049648(SH3KBP1)
CSYR: 103258039(SH3KBP1)
MMUR: 105882372(SH3KBP1)
OGA: 100960167(SH3KBP1)
MMU: 58194(Sh3kbp1)
MCAL: 110286205(Sh3kbp1)
MPAH: 110314275(Sh3kbp1)
RNO: 84357(Sh3kbp1)
MCOC: 116090164(Sh3kbp1)
CGE: 100750373(Sh3kbp1)
PLEU: 114695792(Sh3kbp1)
NGI: 103736227(Sh3kbp1)
HGL: 101717745(Sh3kbp1)
CPOC: 100720414(Sh3kbp1)
DORD: 105993305(Sh3kbp1)
DSP: 122100104(Sh3kbp1)
NCAR: 124971975
OCU: 100357864(SH3KBP1)
OPI: 101523325(SH3KBP1)
TUP: 102467955(SH3KBP1)
VVP: 112919125(SH3KBP1)
VLG: 121482233(SH3KBP1)
AML: 100471577(SH3KBP1)
UMR: 103668167(SH3KBP1)
UAH: 113242243(SH3KBP1)
UAR: 123794855(SH3KBP1)
ELK: 111150333
LLV: 125091617
MPUF: 101687817(SH3KBP1)
ORO: 101385688(SH3KBP1)
EJU: 114223630(SH3KBP1)
ZCA: 113931079(SH3KBP1)
MLX: 118007461(SH3KBP1)
PYU: 121025627(SH3KBP1)
PBG: 122477521(SH3KBP1)
PTG: 102963969(SH3KBP1)
PPAD: 109256385(SH3KBP1)
AJU: 106981923(SH3KBP1)
HHV: 120241965(SH3KBP1)
BTA: 510489(SH3KBP1)
BOM: 102276186(SH3KBP1)
BIU: 109555281(SH3KBP1)
BBUB: 102413085(SH3KBP1)
CHX: 102186673(SH3KBP1)
ODA: 120882522(SH3KBP1)
CCAD: 122435334(SH3KBP1)
SSC: 100522530(SH3KBP1)
CFR: 102523996(SH3KBP1)
CBAI: 105068632(SH3KBP1)
CDK: 105095312(SH3KBP1)
VPC: 102533368(SH3KBP1)
BACU: 103016032(SH3KBP1)
LVE: 103089062(SH3KBP1)
OOR: 101269186(SH3KBP1)
DLE: 111170377(SH3KBP1)
PSIU: 116746949(SH3KBP1)
ECB: 100058644(SH3KBP1)
EAI: 106835502(SH3KBP1)
MYB: 102245537(SH3KBP1)
MYD: 102765399(SH3KBP1)
MMYO: 118653831(SH3KBP1)
MLF: 102435213(SH3KBP1)
MNA: 107526788(SH3KBP1)
PKL: 118719847(SH3KBP1)
HAI: 109395884(SH3KBP1)
DRO: 112313329(SH3KBP1)
SHON: 118987202(SH3KBP1)
AJM: 119058360(SH3KBP1)
PDIC: 114504690(SH3KBP1)
PHAS: 123830054(SH3KBP1)
MMF: 118635958(SH3KBP1)
RFQ: 117026143(SH3KBP1)
PALE: 102882213(SH3KBP1)
PGIG: 120594295(SH3KBP1)
PVP: 105294028(SH3KBP1)
RAY: 107500167(SH3KBP1)
MJV: 108400932(SH3KBP1)
TOD: 119246291(SH3KBP1)
SARA: 101542853(SH3KBP1)
LAV: 100657462(SH3KBP1)
TMU: 101361453
DNM: 101435239(SH3KBP1)
MDO: 100013895(SH3KBP1)
GAS: 123242406(SH3KBP1)
SHR: 100932601(SH3KBP1)
PCW: 110210840(SH3KBP1)
OAA: 100083478(SH3KBP1)
GGA: 418608(SH3KBP1)
PCOC: 116232758(SH3KBP1)
MGP: 100551401(SH3KBP1)
CJO: 107325446(SH3KBP1)
NMEL: 110404639(SH3KBP1)
APLA: 101791340(SH3KBP1)
ACYG: 106037808(SH3KBP1)
AFUL: 116486119(SH3KBP1)
TGU: 100225064(SH3KBP1)
LSR: 110483220(SH3KBP1)
SCAN: 103815842(SH3KBP1)
PMOA: 120504523(SH3KBP1)
OTC: 121333482(SH3KBP1)
PRUF: 121356158(SH3KBP1)
FAB: 101810014(SH3KBP1)
PHI: 102112220(SH3KBP1)
PMAJ: 107207656(SH3KBP1)
CCW: 104686184(SH3KBP1)
ETL: 114058908(SH3KBP1)
ZAB: 102069330(SH3KBP1)
CLV: 102088281(SH3KBP1)
ACUN: 113480332(SH3KBP1)
TALA: 104367093(SH3KBP1)
PADL: 103918222(SH3KBP1)
ACHC: 115343764(SH3KBP1)
AAM: 106492038(SH3KBP1)
AROW: 112960531
NPD: 112958333(SH3KBP1)
DNE: 112995642(SH3KBP1)
ASN: 102368193(SH3KBP1)
AMJ: 102573255(SH3KBP1)
CPOO: 109305993(SH3KBP1)
GGN: 109302880(SH3KBP1)
PSS: 102451260(SH3KBP1)
CMY: 102935495(SH3KBP1)
CPIC: 101941882(SH3KBP1)
TST: 117869158(SH3KBP1)
CABI: 116823447(SH3KBP1)
MRV: 120394495 120400488(SH3KBP1)
ACS: 100551600(sh3kbp1)
PVT: 110076718(SH3KBP1)
SUND: 121926098(SH3KBP1)
PBI: 103060890(SH3KBP1)
PMUR: 107295918(SH3KBP1)
TSR: 106539793(SH3KBP1)
PGUT: 117675453(SH3KBP1)
VKO: 123029091(SH3KBP1)
PMUA: 114596238(SH3KBP1)
ZVI: 118085794(SH3KBP1)
STOW: 125430946(SH3KBP1)
XLA: 108705547 108708009 108709328(sh3kbp1.S)
XTR: 100151706(sh3kbp1)
NPR: 108785715(SH3KBP1)
RTEM: 120927509(SH3KBP1)
BBUF: 120994843(SH3KBP1)
BGAR: 122930519(SH3KBP1)
DRE: 793623(sh3kbp1)
SANH: 107663662(sh3kbp1)
SGH: 107586741(sh3kbp1) 107590295
PPRM: 120488312(sh3kbp1)
MAMB: 125258015(sh3kbp1)
IPU: 108256316(sh3kbp1)
PHYP: 113541186(sh3kbp1)
SMEO: 124403683(sh3kbp1)
TFD: 113660345(sh3kbp1)
AMEX: 103025305(sh3kbp1)
EEE: 113576138(sh3kbp1)
TRU: 101076581(sh3kbp1)
LCO: 104940023(sh3kbp1)
NCC: 104949750
CGOB: 115025542(sh3kbp1)
ELY: 117264811(sh3kbp1)
PLEP: 121960486(sh3kbp1)
SLUC: 116048548(sh3kbp1)
ECRA: 117937773(sh3kbp1)
PFLV: 114549643(sh3kbp1)
GAT: 120811531(sh3kbp1)
PPUG: 119198986(sh3kbp1)
MSAM: 119912491(sh3kbp1)
CUD: 121527552(sh3kbp1)
MZE: 101486118(sh3kbp1)
ONL: 100692237(sh3kbp1)
OAU: 116324431(sh3kbp1)
OLA: 101157013(sh3kbp1)
OML: 112151195(sh3kbp1)
XMA: 102222214(sh3kbp1)
XCO: 114136721(sh3kbp1)
XHE: 116711820(sh3kbp1)
PRET: 103456752(sh3kbp1)
PFOR: 103140537(sh3kbp1)
PLAI: 106935767
PMEI: 106914951(sh3kbp1)
GAF: 122823951(sh3kbp1)
CVG: 107094812(sh3kbp1)
CTUL: 119771467(sh3kbp1)
GMU: 124858089(sh3kbp1)
NFU: 107383063(sh3kbp1)
KMR: 108234731(sh3kbp1)
ALIM: 106515508(sh3kbp1)
NWH: 119426854(sh3kbp1)
AOCE: 111570229
CSEM: 103377322(sh3kbp1)
POV: 109644971
SSEN: 122780371(sh3kbp1)
HHIP: 117754191(sh3kbp1)
LCF: 108885108(sh3kbp1)
SDU: 111224324(sh3kbp1)
SLAL: 111645765(sh3kbp1)
XGL: 120789579(sh3kbp1)
HCQ: 109524704(sh3kbp1)
BPEC: 110161275(sh3kbp1)
MALB: 109961080(sh3kbp1)
SASA: 100195508(sh3k1) 106579452
OTW: 112247514
OMY: 110489648 110535365(sh3kbp1)
OGO: 123991296(sh3kbp1) 124039537
ONE: 115122943(sh3kbp1) 115130113
SNH: 120027966(sh3kbp1) 120050962
ELS: 105021977(sh3kbp1)
SFM: 108927718(sh3kbp1)
PKI: 111836770(sh3kbp1)
AANG: 118224988(sh3kbp1)
LOC: 102697728
PSPA: 121302900(sh3kbp1)
LCM: 102358503(SH3KBP1)
CMK: 103177511(sh3kbp1)
RTP: 109930959(sh3kbp1)
BFO: 118423203
CIN: 100186262
SCLV: 120338480
SPU: 581235
AGB: 108907708
LDC: 111510595
PJA: 122256648
PCHN: 125046221
PCLA: 123764361
PTRU: 123499561
HAZT: 108681519
LSM: 121125040
DSV: 119460687
RSAN: 119396526
RMP: 119174706
VDE: 111246315
VJA: 111268937
SDM: 118182155
BGT: 106064565
GAE: 121372562
HRF: 124147359
HRJ: 124282488
MMER: 123552352
EGL: EGR_02797
NVE: 5510294
XEN: 124442483
HMG: 100211329
 » show all
Reference
  Authors
Kowanetz K, Husnjak K, Holler D, Kowanetz M, Soubeyran P, Hirsch D, Schmidt MH, Pavelic K, De Camilli P, Randazzo PA, Dikic I
  Title
CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors.
  Journal
Mol Biol Cell 15:3155-66 (2004)
DOI:10.1091/mbc.E03-09-0683
  Sequence
[hsa:30011]
Reference
  Authors
Aissouni Y, Zapart G, Iovanna JL, Dikic I, Soubeyran P
  Title
CIN85 regulates the ability of MEKK4 to activate the p38 MAP kinase pathway.
  Journal
Biochem Biophys Res Commun 338:808-14 (2005)
DOI:10.1016/j.bbrc.2005.10.032
  Sequence
[hsa:30011]

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