KEGG   ORTHOLOGY: K12490
Entry
K12490                      KO                                     
Symbol
ARAP3
Name
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Pathway
map04015  Rap1 signaling pathway
map04024  cAMP signaling pathway
map04144  Endocytosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
   04024 cAMP signaling pathway
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Membrane trafficking [BR:ko04131]
 Endocytosis
  Arf GTPases and associated proteins
   Arf associated proteins
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 Others
  Rho GTPase associated proteins
   Rho GTPase-activating proteins
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Genes
HSA: 64411(ARAP3)
PTR: 462149(ARAP3)
PPS: 100977768(ARAP3)
GGO: 101137714(ARAP3)
PON: 100437871(ARAP3)
NLE: 100598122(ARAP3)
MCC: 701400(ARAP3)
MCF: 102124624(ARAP3)
CSAB: 103244701(ARAP3)
CATY: 105599935(ARAP3)
PANU: 101001754(ARAP3)
TGE: 112626943(ARAP3)
RRO: 104681826(ARAP3)
RBB: 108530209(ARAP3)
TFN: 117065697(ARAP3)
PTEH: 111526958(ARAP3)
CJC: 100387074(ARAP3)
SBQ: 101037093(ARAP3)
CSYR: 103269885(ARAP3)
MMUR: 105862632(ARAP3)
LCAT: 123637906(ARAP3)
OGA: 100942649(ARAP3)
MMU: 106952(Arap3)
MCAL: 110284610(Arap3)
MPAH: 110333208(Arap3)
RNO: 361314(Arap3)
MCOC: 116087072(Arap3)
MUN: 110557094(Arap3)
CGE: 100752046(Arap3)
MAUA: 101826958(Arap3)
MORG: 121453343(Arap3)
AAMP: 119814639(Arap3)
NGI: 103736075(Arap3)
HGL: 101709044(Arap3)
CPOC: 100721743(Arap3)
CCAN: 109681337(Arap3)
DORD: 105988745(Arap3)
DSP: 122118187(Arap3)
NCAR: 124986802
OCU: 100354264(ARAP3)
OPI: 101529450(ARAP3)
TUP: 102470245(ARAP3)
CFA: 487188(ARAP3)
VVP: 112934640(ARAP3)
VLG: 121497329(ARAP3)
AML: 100465375(ARAP3)
UMR: 103663721(ARAP3)
UAH: 113255371(ARAP3)
UAR: 123790219(ARAP3)
ELK: 111156922
LLV: 125099676
MPUF: 101673908(ARAP3)
ORO: 101366666(ARAP3)
EJU: 114200662(ARAP3)
ZCA: 113929433(ARAP3)
MLX: 118016745(ARAP3)
FCA: 101080259(ARAP3)
PYU: 121016641(ARAP3)
PBG: 122483746(ARAP3)
PTG: 102962215(ARAP3)
PPAD: 109252207(ARAP3)
AJU: 106968226(ARAP3)
HHV: 120234355(ARAP3)
BTA: 112447442(ARAP3)
BOM: 102265022(ARAP3)
BIU: 109561086(ARAP3)
BBUB: 102411515(ARAP3)
CHX: 102184425(ARAP3)
OAS: 101105821(ARAP3)
ODA: 120863533(ARAP3)
CCAD: 122439781(ARAP3)
SSC: 100511744(ARAP3)
CFR: 102511883(ARAP3)
CBAI: 105065468(ARAP3)
CDK: 105090802(ARAP3)
VPC: 102538920(ARAP3)
BACU: 103013330(ARAP3)
LVE: 103082900(ARAP3)
OOR: 101280167(ARAP3)
DLE: 111183025(ARAP3)
PCAD: 102979637(ARAP3)
PSIU: 116751544(ARAP3)
ECB: 100072169(ARAP3)
EPZ: 103550695(ARAP3)
EAI: 106836965(ARAP3)
MYB: 102253252(ARAP3)
MYD: 102761561(ARAP3)
MMYO: 118658849(ARAP3)
MLF: 102436129(ARAP3)
MNA: 107531508(ARAP3)
PKL: 118711329(ARAP3)
HAI: 109393984(ARAP3)
DRO: 112318118(ARAP3)
SHON: 118998505(ARAP3)
AJM: 119051057(ARAP3)
PDIC: 114509280(ARAP3)
PHAS: 123809987(ARAP3)
MMF: 118615668(ARAP3)
RFQ: 117016949(ARAP3)
PALE: 102897313(ARAP3)
PGIG: 120581446(ARAP3)
PVP: 105297072(ARAP3) 105311236
RAY: 107499695(ARAP3)
MJV: 108405531(ARAP3)
TOD: 119243341(ARAP3)
SARA: 101549734(ARAP3)
LAV: 100657212(ARAP3)
TMU: 101357139
DNM: 101415638(ARAP3)
MDO: 100027875(ARAP3)
GAS: 123233833
SHR: 100928929(ARAP3)
PCW: 110220838(ARAP3)
OAA: 100076932(ARAP3)
GGA: 416196(ARAP3)
PCOC: 116231947(ARAP3)
MGP: 100543789(ARAP3)
CJO: 107320281(ARAP3)
NMEL: 110405328(ARAP3)
APLA: 101796955(ARAP3)
ACYG: 106034417(ARAP3)
AFUL: 116494656(ARAP3)
TGU: 100220646(ARAP3)
LSR: 110480255(ARAP3)
SCAN: 103817415(ARAP3)
PMOA: 120499186(ARAP3)
OTC: 121343327(ARAP3)
PRUF: 121354864(ARAP3)
GFR: 102032084(ARAP3)
FAB: 101817352(ARAP3)
PHI: 102108475(ARAP3)
PMAJ: 107210565(ARAP3)
CCAE: 111935703(ARAP3)
CCW: 104696073(ARAP3)
ETL: 114066132(ARAP3)
ZAB: 102067758(ARAP3)
FPG: 101917849(ARAP3)
FCH: 102055065(ARAP3)
CLV: 102092535(ARAP3)
EGZ: 104135761(ARAP3)
NNI: 104016573(ARAP3)
PLET: 104619604(ARAP3)
ACUN: 113485333(ARAP3)
TALA: 104359539(ARAP3)
PADL: 103921971(ARAP3)
ACHC: 115334403(ARAP3)
AAM: 106488076(ARAP3)
AROW: 112968423(ARAP3)
NPD: 112951741(ARAP3)
DNE: 112981820(ARAP3)
ASN: 102385140(ARAP3)
AMJ: 102562874(ARAP3)
CPOO: 109309919(ARAP3)
GGN: 109290172(ARAP3)
CMY: 102941861(ARAP3)
CPIC: 101946704(ARAP3)
TST: 117881555(ARAP3)
CABI: 116820887(ARAP3)
MRV: 120369968(ARAP3)
ACS: 100561635(arap3)
PVT: 110082024(ARAP3)
SUND: 121929327(ARAP3)
PBI: 103057750(ARAP3)
PMUR: 107299164(ARAP3)
TSR: 106547848
VKO: 123029665(ARAP3)
PMUA: 114601098(ARAP3)
ZVI: 118079319(ARAP3)
GJA: 107124863
STOW: 125443754(ARAP3)
XTR: 100492779(arap3)
NPR: 108785748(ARAP3)
RTEM: 120932503(ARAP3)
BBUF: 121008498(ARAP3)
BGAR: 122923256(ARAP3)
DRE: 558931(arap3)
SGH: 107563596 107598344(arap3)
CCAR: 109069922
PPRM: 120460878(arap3)
MAMB: 125259047(arap3)
IPU: 108269111(arap3)
PHYP: 113528795(arap3)
SMEO: 124385924(arap3)
TFD: 113635801(arap3)
AMEX: 103033395
EEE: 113573380
LCO: 104936083(arap3)
CGOB: 115005929(arap3)
ELY: 117261179(arap3)
PLEP: 121947789
SLUC: 116051159(arap3)
PFLV: 114563000(arap3)
GAT: 120817803(arap3)
PPUG: 119211441(arap3)
MSAM: 119888686(arap3)
CUD: 121516165(arap3)
ALAT: 119007164(arap3)
MZE: 101467418(arap3)
ONL: 100711520(arap3)
OAU: 116335513(arap3)
OLA: 101162821(arap3)
OML: 112153181(arap3)
XMA: 102237474(arap3)
XCO: 114139599(arap3)
XHE: 116714578(arap3)
PRET: 103471782(arap3)
PFOR: 103155966(arap3)
PLAI: 106939943
PMEI: 106922903
GAF: 122836767(arap3)
CVG: 107082704(arap3)
CTUL: 119784579(arap3)
GMU: 124860745(arap3)
NFU: 107381061(arap3)
KMR: 108248976(arap3)
ALIM: 106533294
NWH: 119408820(arap3)
AOCE: 111586047(arap3)
CSEM: 103390798(arap3)
POV: 109643191
HHIP: 117769181(arap3)
HSP: 118112323(arap3)
LCF: 108891792
SDU: 111233521(arap3)
SLAL: 111665612(arap3)
XGL: 120785040(arap3)
HCQ: 109508299(arap3)
BPEC: 110168021
MALB: 109956747(arap3)
BSPL: 114864033(arap3)
OTW: 112239485(arap3) 112255862
OMY: 110487789 110504357(arap3)
OGO: 123993734(arap3) 124011592
SNH: 120047880(arap3) 120062170
ELS: 105007474(arap3)
SFM: 108922908(arap3)
PKI: 111836366(arap3)
AANG: 118223265(arap3)
LOC: 102692407(arap3)
LCM: 102359686(ARAP3)
CMK: 103184169(arap3)
 » show all
Reference
  Authors
Krugmann S, Williams R, Stephens L, Hawkins PT
  Title
ARAP3 is a PI3K- and rap-regulated GAP for RhoA.
  Journal
Curr Biol 14:1380-4 (2004)
DOI:10.1016/j.cub.2004.07.058
Reference
  Authors
Krugmann S, Anderson KE, Ridley SH, Risso N, McGregor A, Coadwell J, Davidson K, Eguinoa A, Ellson CD, Lipp P, Manifava M, Ktistakis N, Painter G, Thuring JW, Cooper MA, Lim ZY, Holmes AB, Dove SK, Michell RH, Grewal A, Nazarian A, Erdjument-Bromage H, Tempst P, Stephens LR, Hawkins PT
  Title
Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices.
  Journal
Mol Cell 9:95-108 (2002)
DOI:10.1016/S1097-2765(02)00434-3
  Sequence
[hsa:64411]

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