KEGG ORTHOLOGY: K12587

ORTHOLOGY: K12587

Entry

K12587                      KO

Symbol

MTR3, EXOSC6

Name

exosome complex component MTR3

Pathway

map03018

RNA degradation

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    K12587  MTR3, EXOSC6; exosome complex component MTR3
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K12587  MTR3, EXOSC6; exosome complex component MTR3
Messenger RNA biogenesis [BR:ko03019]
Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    Core exosome factors
     K12587  MTR3, EXOSC6; exosome complex component MTR3

Other DBs

COG:

COG0689

Genes

HSA:	118460(EXOSC6)

PTR:	468014(EXOSC6)

PPS:	100970806 117976295(EXOSC6)

GGO:	101134561(EXOSC6)

PON:	100455722(EXOSC6)

NLE:	100594136 115838603(EXOSC6)

MCC:	712669(EXOSC6)

MCF:	102137221(EXOSC6)

CSAB:

103233151(EXOSC6)

CATY:

105575359(EXOSC6)

PANU:

101008978(EXOSC6)

TGE:	112614404(EXOSC6)

RRO:	104677855(EXOSC6)

RBB:	108527378(EXOSC6)

TFN:	117088038(EXOSC6)

PTEH:

111536143(EXOSC6)

CJC:	100399403(EXOSC6)

SBQ:	101044345(EXOSC6)

MMUR:

105875437(EXOSC6)

OGA:	100942300(EXOSC6)

MMU:	72544(Exosc6)

MCAL:

110300427(Exosc6)

MPAH:

110337567(Exosc6)

RNO:	307850(Exosc6)

MCOC:

116070189(Exosc6)

MUN:	110546020(Exosc6)

CGE:	113834673(Exosc6)

PLEU:

114708066(Exosc6)

NGI:	103725681(Exosc6)

HGL:	101718639(Exosc6)

CPOC:

100728313 101788453(Exosc6)

CCAN:

109684980(Exosc6)

DORD:

105983066(Exosc6)

DSP:	122126076(Exosc6)

NCAR:

124966474

OCU:	108176744(EXOSC6)

CFA:	489713(EXOSC6)

VVP:	112929538(EXOSC6)

VLG:	121500033(EXOSC6)

AML:	117795089(EXOSC6)

UAH:	113252479(EXOSC6)

UAR:	123800525(EXOSC6)

ELK:

111153041

LLV:

125089912

ORO:	101380931(EXOSC6)

EJU:	114202050(EXOSC6)

ZCA:	113936691(EXOSC6)

MLX:	118023577(EXOSC6)

FCA:	101095147(EXOSC6)

PYU:	121009786(EXOSC6)

PBG:	122494454(EXOSC6)

PPAD:

109270634(EXOSC6)

AJU:	113604349(EXOSC6)

HHV:	120224691(EXOSC6)

BTA:	100126247(EXOSC6)

BBUB:

102396991(EXOSC6)

CHX:	108637949(EXOSC6)

OAS:	101115396(EXOSC6)

ODA:	120873344(EXOSC6)

CCAD:

122421126(EXOSC6)

SSC:	100737302(EXOSC6)

CFR:	116665808(EXOSC6)

CDK:	105097713(EXOSC6)

VPC:	102537774(EXOSC6)

LVE:	103072771(EXOSC6)

OOR:	101282155(EXOSC6)

DLE:	111179524(EXOSC6)

PCAD:

112065208(EXOSC6)

PSIU:

116743432(EXOSC6)

ECB:	111772793(EXOSC6)

EAI:	106823434(EXOSC6)

MMYO:

118674415(EXOSC6)

MLF:	102424824(EXOSC6)

MNA:	107525294(EXOSC6)

PKL:	118720760(EXOSC6)

HAI:	109384819(EXOSC6)

DRO:	112300675(EXOSC6)

SHON:

118999229(EXOSC6)

AJM:	119055882(EXOSC6)

PDIC:

114488187(EXOSC6)

PHAS:

123805932(EXOSC6)

MMF:	118639147(EXOSC6)

RFQ:	117034431(EXOSC6)

PGIG:

120598447(EXOSC6)

PVP:	105311145(EXOSC6)

RAY:	107520525(EXOSC6)

MJV:	108408033(EXOSC6)

TOD:	119249064(EXOSC6)

LAV:	100673117(EXOSC6)

TMU:

101350608

DNM:	101423282(EXOSC6)

MDO:	100012149 103106710(EXOSC6)

GAS:	123233212(EXOSC6) 123253828

SHR:	100921118 116421279(EXOSC6)

PCW:	110192536(EXOSC6) 110197724

OAA:	114815203(EXOSC6)

GGA:	107052160(EXOSC6)

PCOC:

116243820(EXOSC6)

CJO:	107319124(EXOSC6)

NMEL:

110404413(EXOSC6)

APLA:

113844805(EXOSC6)

AFUL:

116493903(EXOSC6)

TGU:	115496766(EXOSC6)

LSR:	110476259(EXOSC6)

SCAN:

103816840(EXOSC6)

PMOA:

120508026(EXOSC6)

OTC:	121333834(EXOSC6)

PRUF:

121348789(EXOSC6)

PHI:	102102269(EXOSC6)

PMAJ:

107209970(EXOSC6)

CCW:	120410592(EXOSC6)

ETL:	114068148(EXOSC6)

ZAB:	102068521(EXOSC6)

TALA:

122153902(EXOSC6)

ACHC:

115345726(EXOSC6)

DNE:	112985434(EXOSC6)

CMY:	119563708(EXOSC6)

CABI:

116833725(EXOSC6)

MRV:	120384218(EXOSC6)

ACS:	103280040(exosc6)

SUND:

121914517(EXOSC6)

PMUR:

107292565(EXOSC6)

TSR:	106552876(EXOSC6)

PGUT:

117670495(EXOSC6)

VKO:	123022363(EXOSC6)

PMUA:

114602314(EXOSC6)

ZVI:	118086804(EXOSC6)

GJA:	107121794(EXOSC6)

XLA:	108714148(exosc6.L)

XTR:	549770(exosc6)

NPR:	108798357(EXOSC6)

RTEM:

120940176(EXOSC6)

BBUF:

120980952(EXOSC6)

BGAR:

122920809(EXOSC6)

DRE:	326786(exosc6)

SRX:	107741396 107750522

SANH:

107674447 107700409

SGH:	107586042 107593174

CCAR:

109093173 109093181

CAUA:

113049498(exosc6)

PPRM:

120473151(exosc6)

IPU:	108271352(exosc6)

PHYP:

113536370(exosc6)

SMEO:

124391311(exosc6)

TFD:	113645962(exosc6)

AMEX:

103033271(exosc6)

EEE:	113579117(exosc6)

TRU:	101076452(exosc6)

TNG:	GSTEN00006547G001 GSTEN00006548G001

LCO:	104929141(exosc6)

NCC:	104957510(exosc6)

CGOB:

115009350(exosc6)

ELY:	117262404(exosc6)

PLEP:

121940588 121950557(exosc6)

SLUC:

116053009(exosc6)

ECRA:

117948452(exosc6)

PFLV:

114560555(exosc6)

GAT:	120809022(exosc6)

PPUG:

119195857(exosc6)

MSAM:

119893524(exosc6)

CUD:	121515208(exosc6)

MZE:	101479853(exosc6)

ONL:	100693135(exosc6)

OAU:	116315815(exosc6)

OLA:	101155271(exosc6)

OML:	112152264(exosc6)

XMA:	102231396(exosc6)

XCO:	114136134(exosc6)

XHE:	116731302(exosc6)

PRET:

103466754(exosc6)

PFOR:

103148666(exosc6)

PLAI:

106946286(exosc6)

PMEI:

106923917(exosc6)

GAF:	122836131(exosc6)

CVG:	107081584 107081586

CTUL:

119776348(exosc6)

GMU:	124856677(exosc6)

NFU:	107389150(exosc6)

KMR:	108251121(exosc6)

ALIM:

106526111(exosc6)

NWH:	119415452(exosc6)

AOCE:

111576592(exosc6)

CSEM:

103379512(exosc6)

POV:	109641519(exosc6)

SSEN:

122775692(exosc6)

HHIP:

117763611(exosc6)

LCF:	108901894(exosc6)

SDU:	111225229(exosc6)

SLAL:

111651582(exosc6)

XGL:	120793734(exosc6)

HCQ:	109526854(exosc6)

BPEC:

110169714(exosc6)

MALB:

109962524(exosc6)

SASA:

100196172(exosc6)

OTW:	112218512(exosc6)

OMY:	110494646(exosc6)

OGO:	124037505(exosc6)

ONE:	115134310(exosc6)

SALP:

112069686(exosc6)

SNH:	120066667(exosc6)

ELS:	105018505(exosc6)

SFM:	108933978(exosc6)

PKI:	111848084(exosc6)

AANG:

118228359(exosc6)

LOC:	102689147(exosc6)

PSPA:

121296056(exosc6) 121325587

ARUT:

117424723(exosc6)

CMK:	103173320(exosc6)

RTP:	109914206 109935162 109935165

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

SKO:

DME:	Dmel_CG8025(Mtr3)

DER:

6545758

DSE:

6619418

DSI:	Dsimw501_GD12240(Dsim_GD12240)

DYA:	Dyak_GE22455 Dyak_GE23007

DAN:

6493707

DSR:

110178904

DPO:	Dpse_GA20773

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI13661

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

MDE:

SCAC:

LCQ:

AGA:	AgaP_AGAP011906

ACOZ:

AARA:

AAG:

AALB:

CQU:	CpipJ_CPIJ018069 CpipJ_CPIJ018071

CPII:

CNS:

AME:

ACER:

ALAB:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BPYO:

CCAL:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CCIN:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_204548 KGM_204549

BANY:

PPOT:

PXU:

PRAP:

ZCE:

HAW:

TNL:

SLIU:

OFU:

PXY:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

PHU:	Phum_PHUM613920

FOC:

ZNE:

CSEC:

FCD:

DPX:	DAPPUDRAFT_50975

DMK:

PVM:

PJA:

PCHN:

HAME:

PCLA:

PTRU:

HAZT:

EAF:	111707401 111717610

DSV:

RSAN:

RMP:

VDE:

VJA:

CEL:	CELE_Y6D11A.1(exos-4.2)

BMY:	BM_BM6288(Bma-exos-4.2)

LOA:	LOAG_05308

TSP:

Tsp_05854

LGI:	LOTGIDRAFT_236786

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

MYI:

PMAX:

MMER:

OBI:

OSN:

LAK:

OVI:	T265_13360

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

TAD:	TRIADDRAFT_61054

AQU:

105311947

ATH:	AT4G27490(RRP41L)

ALY:

9303574

CRB:

17879141

CSAT:

104717485 104722172 104730626

EUS:	EUTSA_v10026036mg

BRP:

103867212

BNA:	106376109 106445923

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10029091mg

PVY:

MINC:

TCC:

GRA:

GHI:	107906248 107959013

GAB:

108450595

DZI:	111286228 111301466

EGR:

104421643

GMX:	100816271 100819105

GSJ:	114373989 114378365

PVU:	PHAVU_011G080900g

VRA:

VAR:

VUN:

CCAJ:

APRC:

MTR:	MTR_4g058720

CAM:

101497104

LJA:	Lj0g3v0300669.1(Lj0g3v0300669.1)

ADU:	107476975 107478276

AIP:	107629235 107630131

AHF:	112736483 112737836 112785858 112789963

LANG:

109325620 109351671 109362624

FVE:

101290719

RCN:	112166948 112194695

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103423076 103447898

PXB:	103956748 103962022

MNT:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:	110635016 110642332 110642346

MESC:

110612944

POP:	18098212 7491150

PEU:	105137034 105139604

PALZ:

118034759 118038838

JRE:

109008593

QSU:	111995298 112010785

QLO:

115983204

TWL:	120001855 120014633

VVI:

VRI:

SLY:

SPEN:

SOT:

CANN:

NTA:	107816340 107827829

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

EGT:

SSPL:

121742908 121781611 121806258

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

BVG:

SOE:

CQI:	110724951 110738430

NNU:

MING:

TSS:

PSOM:

NCOL:

OSA:	4344519 9269241

DOSA:

Os03t0844450-01(Os03g0844450) Os08t0116800-01(Os08g0116800)

OBR:

102719888

BDI:

100831709

ATS:

109778172

TDC:	119353697 119362872

TAES:

123044104 123051987 123187854

SBI:

ZMA:

SITA:

SVS:

PVIR:

PHAI:

EGU:

MUS:

DCT:

PEQ:

AOF:

ATR:

SMO:	SELMODRAFT_441621 SELMODRAFT_80529

PPP:

112280138

VCN:	VOLCADRAFT_89262

MNG:

MNEG_3159

CSL:	COCSUDRAFT_59812

CVR:	CHLNCDRAFT_21722

APRO:

F751_2832

BPG:	Bathy06g04300

MIS:	MICPUN_80624

CME:	CYME_CMO206C

GSL:	Gasu_10080

CCP:	CHC_T00010012001

SCE:	YGR158C(MTR3)

SEUB:

DI49_2121

SPAO:

SPAR_G03730

AGO:	AGOS_AFR109W

ERC:

Ecym_6203

KLA:	KLLA0_F18304g

KMX:	KLMA_40104(MTR3)

LTH:	KLTH0D03960g

VPO:	Kpol_1026p19

ZRO:	ZYRO0G07282g

CGR:	CAGL0E03223g

NCS:	NCAS_0A05820(NCAS0A05820)

NDI:	NDAI_0D02820(NDAI0D02820)

TPF:	TPHA_0K01890(TPHA0K01890)

TBL:	TBLA_0C04350(TBLA0C04350)

TDL:	TDEL_0F02890(TDEL0F02890)

TGB:	HG536_0G01910

KAF:	KAFR_0F03140(KAFR0F03140)

KNG:	KNAG_0D03240(KNAG0D03240)

ZMK:	HG535_0B05730

PPA:	PAS_chr1-4_0092

DHA:	DEHA2A12914g

PIC:	PICST_57180(MTR3)

PGU:	PGUG_04029

SPAA:

SPAPADRAFT_134338

LEL:	LELG_00215

CAL:	CAALFM_CR02550CA(CaO19.168)

CTP:	CTRG_00925

COT:	CORT_0A02710

CDU:	CD36_27500

CTEN:

CANTEDRAFT_105628

YLI:	YALI0E06039g

CLUS:

A9F13_02g00627

CAUR:

CJI97_004245

SLB:	AWJ20_3112(MTR3)

PKZ:	C5L36_0C03850

BBRX:

BRETT_000233

OPA:	HPODL_00068

NCR:

NCU08026

NTE:	NEUTE1DRAFT79727(NEUTE1DRAFT_79727)

SMP:	SMAC_03807

PAN:	PODANSg7328

TTT:	THITE_2115125

MTM:	MYCTH_74015

MGR:

MGG_07084

PPEI:

PpBr36_01714

TMN:	UCRPA7_552

SSCK:

SPSK_07783

FGR:	FGSG_04277

FPU:	FPSE_10466

FVR:	FVEG_10467

FOX:	FOXG_20516

NHE:	NECHADRAFT_43918

TRE:	TRIREDRAFT_55589

TRR:	M419DRAFT_70254

MAW:

MAC_09291

MAJ:

MAA_02707

CMT:

CCM_00390

VAL:	VDBG_08232

VDA:	VDAG_10427

CFJ:	CFIO01_00511

CHIG:

CH63R_07696

ELA:	UCREL1_9907

PFY:	PFICI_05705

SSL:	SS1G_08471

BFU:	BCIN_12g02720(Bcmtr3)

MBE:

MBM_04285

PSCO:

LY89DRAFT_661546

GLZ:	GLAREA_10657

ANI:

AN2153.2

AFM:	AFUA_2G15980

ACT:	ACLA_074950

NFI:	NFIA_091240

AOR:	AO090012000203

ANG:	ANI_1_1672134(An15g06320)

AFV:	AFLA_001922

ALUC:

AKAW2_60146A(MTR3)

ACHE:

ACHE_60405A(MTR3)

APUU:

APUU_20452A(MTR3)

PCS:	Pc21g02070

PDP:	PDIP_80630

TMF:	PMAA_084220

TRG:	TRUGW13939_05058

CIM:	CIMG_00317

CPW:	CPC735_058740

PBL:	PAAG_03946

PBN:	PADG_03436

ABE:

ARB_07400

TVE:

TRV_00203

BGH:	BDBG_00844

PNO:	SNOG_08517

PTE:

PTT_14933

BZE:	COCCADRAFT_4058

BSC:	COCSADRAFT_78204

BOR:	COCMIDRAFT_613

AALT:

CC77DRAFT_936644

ZTR:	MYCGRDRAFT_16557

PFJ:	MYCFIDRAFT_56888

FFU:	CLAFUR5_10911

BCOM:

BAUCODRAFT_60118

NPA:	UCRNP2_9728

TML:	GSTUM_00002721001

SPO:	SPBC211.08c

CNE:

CNJ02640

CNB:

CNBJ0820

CNG:	CNAG_04839

CGI:	CGB_I3550C

TMS:	TREMEDRAFT_27507

TVS:	TRAVEDRAFT_164344

DSQ:	DICSQDRAFT_77861

PCO:	PHACADRAFT_161608

SHS:	STEHIDRAFT_145207

HIR:	HETIRDRAFT_471043

PSQ:	PUNSTDRAFT_104997

ADL:	AURDEDRAFT_81203

FME:	FOMMEDRAFT_134856

GTR:	GLOTRDRAFT_72517

LBC:	LACBIDRAFT_187660

MRR:	Moror_6591

E1B28_008838

CCI:	CC1G_04187

SCM:	SCHCODRAFT_50397

ABP:	AGABI1DRAFT97612(AGABI1DRAFT_97612)

ABV:	AGABI2DRAFT63232(AGABI2DRAFT_63232)

CPUT:

CONPUDRAFT_97929

SLA:	SERLADRAFT_473839

WSE:	WALSEDRAFT_59599

WIC:	J056_003868

UMA:	UMAG_04549

PFP:	PFL1_01464

MGL:

MGL_1400

MRT:

MRET_3959

PGR:	PGTG_10390

MLR:	MELLADRAFT_105134

MBR:	MONBRDRAFT_23837

SRE:	PTSG_02318

DDI:	DDB_G0271396

DFA:

DFA_05820

EHI:	EHI_126330(117.t00038) EHI_166910(44.t00031)

EDI:	EDI_278500

EIV:	EIN_155690

ACAN:

ACA1_360300

BBO:	BBOV_III011810(17.m10653)

TGO:	TGME49_319650

TET:	TTHERM_00584730

PTI:	PHATRDRAFT_12322

FCY:	FRACYDRAFT_152761

TPS:	THAPSDRAFT_25487

PIF:	PITG_14853

PSOJ:

PHYSODRAFT_512336

SPAR:

SPRG_10840

EHX:	EMIHUDRAFT_357768 EMIHUDRAFT_440617

GTT:	GUITHDRAFT_49759

TBR:	Tb11.01.2820

TBG:	TbgDal_XI12360

TCR:	507841.34 508269.60

LMA:	LMJF_36_4895

LIF:	LINJ_36_5120

LDO:	LDBPK_365120

LMI:	LMXM_36_4895

LBZ:	LBRM_35_5140

LPAN:

LPMP_355010

NGR:	NAEGRDRAFT_34909

» show all

Reference

PMID:17942686

Authors

Wang HW, Wang J, Ding F, Callahan K, Bratkowski MA, Butler JS, Nogales E, Ke A

Title

Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing.

Journal

Proc Natl Acad Sci U S A 104:16844-9 (2007)
DOI:10.1073/pnas.0705526104

Sequence

[sce:YGR158C]

Reference

PMID:21255825

Authors

Basu U, Meng FL, Keim C, Grinstein V, Pefanis E, Eccleston J, Zhang T, Myers D, Wasserman CR, Wesemann DR, Januszyk K, Gregory RI, Deng H, Lima CD, Alt FW

Title

The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates.

Journal

Cell 144:353-63 (2011)
DOI:10.1016/j.cell.2011.01.001

Sequence

[hsa:118460] [mmu:72544]

All links

Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (1831)   
   KEGG GENES (723)   
   KEGG MGENES (107)   
   RefGene (969)   
   OC (32)   
Literature (2)   
   PubMed (2)   
All databases (1838)   

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