KEGG   ORTHOLOGY: K12641
Entry
K12641                      KO                                     

Name
LMNA
Definition
lamin A/C
Pathway
ko04210  Apoptosis
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Disease
H00264  Charcot-Marie-Tooth disease
H00294  Dilated cardiomyopathy
H00420  Familial partial lipodystrophy
H00563  Emery-Dreifuss muscular dystrophy
H00590  Congenital muscular dystrophies (CMD/MDC)
H00593  Limb-girdle muscular dystrophy
H00601  Hutchinson-Gilford progeria syndrome
H00663  Restrictive dermopathy
H00665  Mandibuloacral dysplasia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K12641  LMNA; lamin A/C
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy (HCM)
    K12641  LMNA; lamin A/C
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K12641  LMNA; lamin A/C
   05414 Dilated cardiomyopathy (DCM)
    K12641  LMNA; lamin A/C
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12641  LMNA; lamin A/C
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Type V: Nuclear lamins
     K12641  LMNA; lamin A/C
Other DBs
GO: 0005638
Genes
HSA: 4000(LMNA)
PTR: 457385(LMNA)
PPS: 100982001(LMNA)
GGO: 101139250(LMNA)
PON: 100432939(LMNA)
NLE: 100603145(LMNA)
MCC: 719414(LMNA)
MCF: 102125659(LMNA)
CSAB: 103223838(LMNA)
RRO: 104664914(LMNA)
RBB: 108515510(LMNA)
CJC: 100401580(LMNA)
SBQ: 101052183(LMNA)
MMU: 16905(Lmna)
MCAL: 110290577(Lmna)
MPAH: 110319753(Lmna)
RNO: 60374(Lmna)
MUN: 110548973(Lmna)
CGE: 100757316(Lmna)
NGI: 103750617(Lmna)
HGL: 101704567(Lmna)
CCAN: 109690469(Lmna)
OCU: 100343574(LMNA)
TUP: 102492596(LMNA)
CFA: 480124(LMNA)
VVP: 112918941(LMNA)
AML: 100469629(LMNA)
UAH: 113245246(LMNA)
ORO: 101383303(LMNA)
ELK: 111138934
FCA: 101086199(LMNA)
PTG: 102967799(LMNA)
PPAD: 109256198(LMNA)
AJU: 106981532(LMNA)
BTA: 404144(LMNA)
BOM: 102280217(LMNA)
BIU: 109553357(LMNA)
BBUB: 102391844(LMNA)
CHX: 102175347(LMNA)
OAS: 101107924(LMNA)
SSC: 100126859(LMNA)
CFR: 102520067(LMNA)
CDK: 105105658(LMNA)
BACU: 103007926(LMNA)
LVE: 103081139(LMNA)
OOR: 101283048(LMNA)
DLE: 111167038(LMNA)
PCAD: 102977546(LMNA)
ECB: 100057663(LMNA)
EPZ: 103548822(LMNA)
EAI: 106828474(LMNA)
MYB: 102262486(LMNA)
MYD: 102769953(LMNA)
MNA: 107543855(LMNA)
HAI: 109393421(LMNA)
DRO: 112317116(LMNA)
PALE: 102884955(LMNA)
RAY: 107521499(LMNA)
MJV: 108405074(LMNA)
LAV: 100662965(LMNA)
TMU: 101345325
MDO: 100017764(LMNA)
SHR: 100923083(LMNA)
PCW: 110211929(LMNA)
OAA: 100083904 100086283(LMNA)
GGA: 396224
CJO: 107324328(LMNA)
APLA: 101797969(LMNA)
ACYG: 106043362 106048973(LMNA)
TGU: 100218522(LMNA)
LSR: 110471509(LMNA)
SCAN: 103823973(LMNA)
GFR: 102031639(LMNA)
FAB: 101813508(LMNA)
PHI: 102101987(LMNA)
PMAJ: 107214592(LMNA)
CCAE: 111934075 111939453(LMNA)
CCW: 104683093(LMNA) 104683962
ETL: 114059050 114069941(LMNA)
FPG: 101917244 101917405(LMNA)
FCH: 102046592 102055756(LMNA)
EGZ: 104124057(LMNA) 104130803
NNI: 104011915(LMNA) 104017250
ACUN: 113490856(LMNA)
AAM: 106492305(LMNA) 106496418
CMY: 102941203 102948145(LMNA)
ACS: 100553155(lmna)
PVT: 110077295 110091219(LMNA)
PBI: 103057051
PMUR: 107297417(LMNA) 107301596
TSR: 106545779
PMUA: 114584865 114586391(LMNA)
GJA: 107118044(LMNA) 107123876
XLA: 108700440 108700617 373673(lmna.L)
XTR: 733973(lmna)
NPR: 108799663(LMNA)
DRE: 195815(lmna)
IPU: 108267994(lmna)
PHYP: 113533930(lmna)
AMEX: 103035739
EEE: 113571231
LCO: 104928071 104932162(lmna)
NCC: 104941814(lmna) 104964806
MZE: 101466330(lmna) 101476203
ONL: 100696816(lmna) 109200181
PRET: 103473032 103477552(lmna)
CVG: 107090817 107104047(lmna)
NFU: 107379121(lmna) 107394894
KMR: 108248891(lmna) 108250646
ALIM: 106528028(lmna) 106530099
AOCE: 111569146 111578023(lmna)
POV: 109643006(lmna) 109644093
LCF: 108899256 108899430(lmna)
SDU: 111220840 111222569(lmna)
SLAL: 111645579 111655682(lmna)
HCQ: 109513571 109521011(lmna)
MALB: 109958689 109974709(lmna)
SFM: 108926783(lmna) 108930411
PKI: 111838402(lmna) 111853505
LCM: 102359604(LMNA)
CMK: 103187531
RTP: 109913313
SPU: 591420
APLC: 110975488
FCD: 110849486
CRG: 105322429
EGL: EGR_02565
NVE: 5511471
ADF: 107353728
SPIS: 111343885
SPAR: SPRG_14046
 » show all
Reference
  Authors
De Vos WH, Houben F, Hoebe RA, Hennekam R, van Engelen B, Manders EM, Ramaekers FC, Broers JL, Van Oostveldt P
  Title
Increased plasticity of the nuclear envelope and hypermobility of telomeres due to the loss of A-type lamins.
  Journal
Biochim Biophys Acta 1800:448-58 (2010)
DOI:10.1016/j.bbagen.2010.01.002
  Sequence
[hsa:4000]

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