KEGG   ORTHOLOGY: K12643
Entry
K12643                      KO                                     
Symbol
ANMT
Name
anthranilate N-methyltransferase [EC:2.1.1.111]
Pathway
map00996  Biosynthesis of various alkaloids
map01110  Biosynthesis of secondary metabolites
Reaction
R00984  S-adenosyl-L-methionine:anthranilate N-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00996 Biosynthesis of various alkaloids
    K12643  ANMT; anthranilate N-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.111  anthranilate N-methyltransferase
     K12643  ANMT; anthranilate N-methyltransferase
Other DBs
GO: 0030774
Genes
CIT: 102626454 102627036
CIC: CICLE_v10020782mg CICLE_v10020818mg
AG: ABI93949(ANMT)
Reference
PMID:17988223
  Authors
Rohde B, Hans J, Martens S, Baumert A, Hunziker P, Matern U
  Title
Anthranilate N-methyltransferase, a branch-point enzyme of acridone biosynthesis.
  Journal
Plant J 53:541-53 (2008)
DOI:10.1111/j.1365-313X.2007.03360.x
  Sequence
[ag:ABI93949]
Reference
  Authors
Eilert U, Wolters B.
  Title
Elicitor induction of S-adenosyl-L-methionine: Anthranilic acid N-methyltransferase activity in cell suspension and organ cultures of Ruta graveolens L.
  Journal
Plant Cell Tissue Organ Cult 18:1-18 (1989)
DOI:10.1007/BF00033461

  All links  
Ontology (1)   
   GO (1)   
Gene (1)   
   OC (1)   
All databases (2)   

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KEGG   ENZYME: 2.1.1.111
Entry
EC 2.1.1.111                Enzyme                                 
Name
anthranilate N-methyltransferase;
anthranilic acid N-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:anthranilate N-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + anthranilate = S-adenosyl-L-homocysteine + N-methylanthranilate [RN:R00984]
Reaction(KEGG)
R00984
Substrate
S-adenosyl-L-methionine [CPD:C00019];
anthranilate [CPD:C00108]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
N-methylanthranilate [CPD:C03005]
Comment
Involved in the biosynthesis of acridine alkaloids in plant tissues.
History
EC 2.1.1.111 created 1992
Pathway
ec00996  Biosynthesis of various alkaloids
ec01110  Biosynthesis of secondary metabolites
Orthology
K12643  anthranilate N-methyltransferase
Genes
CIT: 102626454 102627036
CIC: CICLE_v10020782mg CICLE_v10020818mg
Reference
1
  Authors
Eilert U, Wolters B.
  Title
Elicitor induction of S-adenosyl-L-methionine-anthranilic acid N-methyltransferase activity in cell-suspension and organ-cultures of Ruta graveolens L.
  Journal
Plant Cell, Tissue Organ Cult 18:1-18 (1989)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.111
IUBMB Enzyme Nomenclature: 2.1.1.111
ExPASy - ENZYME nomenclature database: 2.1.1.111
BRENDA, the Enzyme Database: 2.1.1.111
CAS: 123779-15-7

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Protein sequence (7)   
   UniProt (6)   
   SWISS-PROT (1)   
DNA sequence (4)   
   GenBank (2)   
   EMBL (2)   
Protein domain (6)   
   InterPro (6)   
All databases (17)   

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KEGG   REACTION: R00984
Entry
R00984                      Reaction                               
Name
S-adenosyl-L-methionine:anthranilate N-methyltransferase
Definition
S-Adenosyl-L-methionine + Anthranilate <=> S-Adenosyl-L-homocysteine + N-Methylanthranilate
Equation
C00019 + C00108 <=> C00021 + C03005
Reaction class
RC00003  C00019_C00021
RC00335  C00108_C03005
Enzyme
2.1.1.111
Pathway
rn00996  Biosynthesis of various alkaloids
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.111
     R00984  S-Adenosyl-L-methionine + Anthranilate <=> S-Adenosyl-L-homocysteine + N-Methylanthranilate
Orthology
K12643  anthranilate N-methyltransferase [EC:2.1.1.111]
Other DBs
RHEA: 12183

  All links  
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