KEGG ORTHOLOGY: K12794

ORTHOLOGY: K12794

Entry

K12794                      KO

Symbol

CARD9

Name

caspase recruitment domain-containing protein 9

Pathway

map04621

NOD-like receptor signaling pathway

map04625

C-type lectin receptor signaling pathway

map05152

Tuberculosis

map05168

Herpes simplex virus 1 infection

Disease

H01109

Chronic mucocutaneous candidiasis

H02525

Disorders of innate immunity

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K12794  CARD9; caspase recruitment domain-containing protein 9
   04625 C-type lectin receptor signaling pathway
    K12794  CARD9; caspase recruitment domain-containing protein 9
09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K12794  CARD9; caspase recruitment domain-containing protein 9
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K12794  CARD9; caspase recruitment domain-containing protein 9

Genes

HSA:	64170(CARD9)

PTR:	464917(CARD9)

PPS:	100974776(CARD9)

GGO:	129524515(CARD9)

PON:	100447342(CARD9)

PPYG:

129044521(CARD9)

NLE:	100585473(CARD9)

HMH:	116475862(CARD9)

SSYN:

129478687(CARD9)

MCC:	710485(CARD9)

MCF:	102144092(CARD9)

MTHB:

126936954

MNI:	105471929(CARD9)

CSAB:

103239631(CARD9)

CATY:

105580567(CARD9)

PANU:

100997650(CARD9)

TGE:	112608008(CARD9)

MLEU:

105543312(CARD9)

RRO:	104669676(CARD9)

RBB:	108542902(CARD9)

TFN:	117099160(CARD9)

PTEH:

111553068(CARD9)

CANG:

105522713(CARD9)

CJC:	100399254(CARD9)

SBQ:	101039669(CARD9)

CIMI:

108287321(CARD9)

ANAN:

105712261(CARD9)

CSYR:

103250615(CARD9)

MMUR:

105880789(CARD9)

LCAT:

123645793(CARD9)

PCOQ:

105818669(CARD9)

OGA:	100945484(CARD9)

MMU:	332579(Card9)

MCAL:

110290226(Card9)

MPAH:

110319340(Card9)

RNO:	64171(Card9)

MCOC:

116089850(Card9)

ANU:	117710136(Card9)

MUN:	110550863(Card9)

CGE:	100759255(Card9)

MAUA:

101839684(Card9)

PROB:

127222625(Card9)

PLEU:

114692817(Card9)

MORG:

121463010(Card9)

MFOT:

126509480

AAMP:

119819217(Card9)

NGI:	103741205(Card9)

HGL:	101726760(Card9)

CPOC:

100713392(Card9)

CCAN:

109699034(Card9)

DORD:

105995655(Card9)

DSP:	122108960(Card9)

PLOP:

125351267(Card9)

NCAR:

124964848

MMMA:

107159128(Card9)

OPI:	101535635(CARD9)

TUP:	102480227(CARD9)

GVR:	103590876(CARD9)

CFA:	607492(CARD9)

CLUD:

112677438(CARD9)

VVP:	112906963(CARD9)

VLG:	121473273(CARD9)

NPO:	129494690(CARD9)

AML:	100484878(CARD9)

UMR:	103675278(CARD9)

UAH:	113248575(CARD9)

UAR:	123796355(CARD9)

ELK:

111145916

LLV:

125082910

MPUF:

101679483(CARD9)

MNP:	132024248(CARD9)

MLK:	131813192(CARD9)

NVS:	122916827(CARD9)

ORO:	101382186(CARD9)

EJU:	114203818 114203819

ZCA:	113934589(CARD9)

MLX:	118017524(CARD9)

NSU:	110581279(CARD9)

LWW:	102745495(CARD9)

FCA:	101093152(CARD9)

PYU:	121022862(CARD9)

PBG:	122474624(CARD9)

PVIV:

125150558(CARD9)

LRUF:

124522357

PPAD:

109258814(CARD9)

PUC:

125923292

AJU:

106989568

HHV:	120221976(CARD9)

BTA:	768054(CARD9)

BOM:	102279318(CARD9)

BIU:	109566586(CARD9)

BBUB:

102412615(CARD9)

CHX:	102170987(CARD9)

OAS:

101116303

BTAX:

128056628(CARD9)

ODA:	120852145(CARD9)

CCAD:

122442324(CARD9)

MBEZ:

129539247(CARD9)

SSC:	110258075(CARD9)

CFR:	102516391(CARD9)

CBAI:

105069735(CARD9)

CDK:	105106036(CARD9)

VPC:	102540377(CARD9)

BACU:

102999247(CARD9)

BMUS:

118896878(CARD9)

LVE:	103069387(CARD9)

OOR:	101284636(CARD9)

DLE:	111177041(CARD9)

PCAD:

102983532(CARD9)

PSIU:

116755627(CARD9)

NASI:

112411472(CARD9)

ECB:	100068666(CARD9)

EPZ:	103565351(CARD9)

EAI:	106845553(CARD9)

MMYO:

118655259(CARD9)

MDT:	132212583(CARD9)

PKL:	118707028(CARD9)

EFUS:

103295984(CARD9)

MNA:	107535599(CARD9)

DRO:	112306324(CARD9)

SHON:

118980192(CARD9)

AJM:	119036124(CARD9)

PDIC:

114499649(CARD9)

PHAS:

123823576(CARD9)

MMF:	118629749(CARD9)

PPAM:

129079552(CARD9)

HAI:	109381408(CARD9)

RFQ:	117031760(CARD9)

PALE:

102885522(CARD9)

PGIG:

120599842(CARD9)

PVP:	105298579(CARD9)

RAY:	107514876(CARD9)

MJV:	108387659(CARD9)

TOD:	119232384(CARD9)

SARA:

101551052(CARD9)

SETR:

126009248(CARD9)

LAV:	100658076(CARD9)

TMU:

101361050

ETF:	101651114(CARD9)

DNM:	101416552(CARD9)

MDO:	100020522(CARD9)

GAS:	123237199(CARD9)

SHR:	100931004(CARD9)

AFZ:

127550984

PCW:	110205341(CARD9)

TVP:	118843096(CARD9)

OAA:	100091973(CARD9)

GGA:	427756(CARD9)

PCOC:

116234333(CARD9)

MGP:	100546924(CARD9)

CJO:	107321712(CARD9)

TPAI:

128073107(CARD9)

LMUT:

125702452(CARD9)

NMEL:

110406836(CARD9)

APLA:

101789777(CARD9)

ACYG:

106040752(CARD9)

CATA:

118252109(CARD9)

AFUL:

116496930(CARD9)

TGU:	100219285(CARD9)

LSR:	110477706(CARD9)

SCAN:

103819122(CARD9)

PMOA:

120512457(CARD9)

OTC:	121336881(CARD9)

PRUF:

121362408(CARD9)

GFR:	102040607(CARD9)

FAB:	101815228(CARD9)

OMA:	130260282(CARD9)

PHI:	102113457(CARD9)

PMAJ:

107212153(CARD9)

CCAE:

111937069(CARD9)

CCW:	104688355(CARD9)

CBRC:

103623121(CARD9)

ETL:	114059115(CARD9)

ZAB:	102070389(CARD9)

ZLE:	135454966(CARD9)

ACHL:

103804918(CARD9)

SVG:	106855422(CARD9)

MMEA:

130582251(CARD9)

HRT:	120761733(CARD9)

SATI:

136369810(CARD9)

FPG:	101910390(CARD9)

FCH:	102047013(CARD9)

CCRI:

104162341(CARD9)

NNT:	104408062(CARD9)

SHAB:

115616987(CARD9)

ACUN:

113486525(CARD9)

TALA:

104363119(CARD9)

ACHC:

115335451(CARD9)

HALD:

104318666(CARD9)

HLE:	104833842(CARD9)

AGEN:

126051990

GCL:

127023857

CSTI:

104549606(CARD9)

LDI:	104351926(CARD9)

MNB:	103774529(CARD9)

DPUB:

104306486(CARD9)

AVIT:

104278535(CARD9)

BRHI:

104500467(CARD9)

EGZ:	104129369(CARD9)

NNI:	104023208(CARD9)

PCRI:

104029112(CARD9)

PCAO:

104045459(CARD9)

PADL:

103915252(CARD9)

AFOR:

103900034(CARD9)

FGA:	104081618(CARD9)

GSTE:

104251815(CARD9)

CLV:	102084746(CARD9)

MUI:

104540037

PGUU:

104464637(CARD9)

PLET:

104614656(CARD9)

EHS:	104504134(CARD9)

CMAC:

104475575(CARD9)

CUCA:

104066842(CARD9)

TEO:	104372148(CARD9)

BREG:

104643381(CARD9)

OHA:	104336596(CARD9)

ACAR:

104522268(CARD9)

CPEA:

104389894(CARD9)

CVF:	104292905(CARD9)

RTD:	128917330(CARD9)

AAM:	106487010(CARD9)

AROW:

112964351(CARD9)

NPD:	112955855(CARD9)

TGT:	104575203(CARD9)

DNE:	112979945(CARD9)

SCAM:

104138226(CARD9)

ASN:	102380379(CARD9)

AMJ:	102568355(CARD9)

CPOO:

109314020(CARD9)

GGN:	109293036(CARD9)

PSS:	102448080(CARD9)

CMY:	102935381(CARD9)

CCAY:

125623301(CARD9)

DCC:	122455357(CARD9)

CPIC:

101938655(CARD9)

TST:	117889354(CARD9)

CABI:

116817458(CARD9)

MRV:	120387016(CARD9)

ASAO:

132763798(CARD9)

PVT:	110079621(CARD9)

SUND:

121936811(CARD9)

PBI:	103057226(CARD9)

PMUR:

107292080(CARD9)

CTIG:

120317518(CARD9)

TSR:	106540449(CARD9)

PGUT:

117671297(CARD9)

APRI:

131186169(CARD9)

PTEX:

113448447(CARD9)

NSS:	113427402(CARD9)

VKO:	123035201(CARD9)

PMUA:

114589210(CARD9)

PRAF:

128406544(CARD9)

ZVI:	118083675(CARD9)

HCG:	128339001(CARD9)

EMC:	129341934(CARD9)

XLA:	108698185(card9.L) 108699906(card9.S)

XTR:	100145327(card9)

NPR:	108793109(CARD9)

RTEM:

120913851(CARD9)

BBUF:

120977080(CARD9)

BGAR:

122946065(CARD9)

MUO:	115473025(CARD9)

GSH:	117368309(CARD9)

DRE:	796425(card9)

SRX:	107720211 107756300

SANH:

107699720 107703208

SGH:	107555475 107587541

CCAR:

109067948 109085500

CAUA:

113049615(card9) 113080339

CGIB:

127958103 127998784

PTET:

122345554(card9)

LROH:

127164828(card9)

OMC:	131540960(card9)

PPRM:

120472010(card9)

RKG:	130072666(card9)

MAMB:

125267513(card9)

CIDE:

127512078

CERY:

137034769(card9)

MASI:

127420252 127436938

TROS:

130569219(card9)

TDW:	130418980(card9)

MANU:

129453848(card9)

IPU:

108255884

IFU:	128625530(card9)

PHYP:

113537046(card9)

SMEO:

124380699(card9)

TFD:	113642289(card9)

TVC:	132855242(card9)

TRN:	134335404(card9)

AMEX:

103034770(card9)

CMAO:

118827096(card9)

EEE:	113574995(card9)

CHAR:

105904328(card9)

LCO:	104939982(card9)

TBEN:

117469112(card9)

CGOB:

115006062(card9)

EMAC:

134873417(card9)

ELY:	117252155(card9)

EFO:	125890877(card9)

PLEP:

121938202(card9)

SLUC:

116034445 116058681(card9)

ECRA:

117941351

PFLV:

114555218(card9)

GAT:	120813859 120830798(card9)

PPUG:

119225340(card9)

AFB:	129101453(card9)

CLUM:

117736936(card9)

PSWI:

130196778(card9)

MSAM:

119891561(card9)

SCHU:

122876005(card9)

ALAT:

119020319(card9)

MZE:

101469430

ONL:

102078975

OAU:	116316344(card9)

OLA:	101156662(card9)

OML:	112148878(card9)

CSAI:

133451200(card9)

XMA:	102238337(card9)

XCO:	114144066(card9)

XHE:	116729185(card9)

PRET:

103470783

PFOR:

103131402(card9)

PLAI:

106938220

PMEI:

106904534

GAF:	122828560(card9)

PPRL:

129365764(card9)

CVG:	107097807(card9)

CTUL:

119782410(card9)

GMU:	124877697(card9)

NFU:	107386133(card9)

KMR:	108245830(card9)

ALIM:

106534035(card9)

NWH:	119413780(card9)

AOCE:

111574080(card9)

MCEP:

125011728(card9)

CSEM:

103397944(card9)

POV:	109643706(card9)

SSEN:

122769259(card9)

HHIP:

117767745(card9) 117767756

PPLT:

128438817(card9)

SMAU:

118314326(card9)

LCF:

108894493

SDU:	111237451(card9)

SLAL:

111649131(card9)

XGL:	120787513(card9)

MALB:

109957402(card9)

SASA:

100195248(card9) 106585631

STRU:

115164876 115199787

OTW:	112247679 112263304

OMY:	110525340(card9) 110535743

OGO:	124034573 124035146

ONE:	115111322 115139751

OKI:	109871449 109895646

OKE:	118358047 118394202(card9)

SALP:

111957441 111974701

SNH:	120053965(card9) 120062678

CCLU:

121551332 121584063(card9)

ELS:	105014418(card9)

SFM:	108920151(card9)

PKI:	111848592(card9)

LOC:	102698373(card9)

PSPA:

121309757(card9)

ARUT:

117396946 117422466 117962530

PSEX:

120535064(card9)

LCM:	102356629(CARD9)

CMK:	103184694(card9)

HOC:	132825953(card9)

LERI:

129712083(card9)

BBEL:

CBR:

BGT:

GAE:

PMAX:

EPA:

Reference

PMID:17187069

Authors

Hsu YM, Zhang Y, You Y, Wang D, Li H, Duramad O, Qin XF, Dong C, Lin X

Title

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens.

Journal

Nat Immunol 8:198-205 (2007)
DOI:10.1038/ni1426

Reference

PMID:11053425

Authors

Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL, Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, Alnemri ES

Title

CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B.

Journal

J Biol Chem 275:41082-6 (2000)
DOI:10.1074/jbc.C000726200

Sequence

[hsa:64170]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (560)   
   KEGG GENES (399)   
   KEGG MGENES (143)   
   RefGene (15)   
   OC (3)   
Literature (2)   
   PubMed (2)   
All databases (573)   

Download RDF

DBGET integrated database retrieval system