KEGG ORTHOLOGY: K12799

ORTHOLOGY: K12799

Entry

K12799                      KO

Symbol

PYCARD, ASC

Name

apoptosis-associated speck-like protein containing a CARD

Pathway

map04217

Necroptosis

map04621

NOD-like receptor signaling pathway

map04623

Cytosolic DNA-sensing pathway

map04625

C-type lectin receptor signaling pathway

map05130

Pathogenic Escherichia coli infection

map05131

Shigellosis

map05132

Salmonella infection

map05133

Pertussis

map05134

Legionellosis

map05135

Yersinia infection

map05164

Influenza A

map05417

Lipid and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
   04623 Cytosolic DNA-sensing pathway
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
   04625 C-type lectin receptor signaling pathway
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
   05132 Salmonella infection
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
   05131 Shigellosis
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
   05135 Yersinia infection
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
   05133 Pertussis
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
   05134 Legionellosis
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD

Genes

HSA:	29108(PYCARD)

PTR:	742444(PYCARD)

PPS:	100991103(PYCARD)

GGO:	101128578(PYCARD)

PON:	100437227(PYCARD)

PPYG:

129015789(PYCARD)

NLE:	100593312(PYCARD)

HMH:	116471192(PYCARD)

SSYN:

129492591

MCC:	713563(PYCARD)

MCF:	102144771(PYCARD)

MTHB:

126944252

MNI:	105482961(PYCARD)

CSAB:

103231357

CATY:

105599574(PYCARD)

PANU:

100998153

TGE:	112614297(PYCARD)

MLEU:

105541471(PYCARD)

RRO:	104661576(PYCARD)

RBB:	108528384(PYCARD)

TFN:	117087696(PYCARD)

PTEH:

111525695(PYCARD)

CANG:

105505708(PYCARD)

CJC:	100395878(PYCARD)

SBQ:	101037266(PYCARD)

CIMI:

108293914(PYCARD)

ANAN:

105729276(PYCARD)

CSYR:

103264397(PYCARD)

MMUR:

105871038

LCAT:

123632689(PYCARD)

PCOQ:

105823116(PYCARD)

OGA:

100949266

MMU:	66824(Pycard)

MCAL:

110299014

MPAH:

110333045

RNO:	282817(Pycard)

MCOC:

116103048

ANU:

117713791

MUN:	110564542(Pycard)

CGE:

MAUA:

PROB:

PLEU:

MORG:

121457950(Pycard)

MFOT:

126515933

AAMP:

119826297

NGI:	103726320(Pycard)

HGL:	101717462(Pycard)

CPOC:

100734858

CCAN:

109682713(Pycard)

DORD:

DSP:

PLOP:

NCAR:

MMMA:

107147167(Pycard)

OCU:

100352110

OPI:

101522554

TUP:	102485294(PYCARD)

GVR:	103610092(PYCARD)

CFA:	100856347(PYCARD)

CLUD:

112640139(PYCARD)

VVP:

VLG:

NPO:

AML:

UMR:

UAH:

UAR:

ELK:

LLV:

MPUF:

MNP:

MLK:

NVS:

ORO:

EJU:

ZCA:	113932810(PYCARD)

MLX:

117999561

NSU:

110589905

LWW:

102727882

FCA:	101088449(PYCARD)

PYU:

PCOO:

PBG:

PVIV:

LRUF:

PTG:	102965910(PYCARD)

PPAD:

PUC:

AJU:

HHV:

BTA:	282846(PYCARD)

BOM:	102270806(PYCARD)

BIU:

BBUB:

BBIS:

CHX:

OAS:

BTAX:

ODA:

CCAD:

MBEZ:

SSC:

CFR:

CBAI:

CDK:

VPC:

BACU:

102999038 103004444(PYCARD)

BMUS:

118881335 118881652

LVE:	103073993 103074128(PYCARD)

OOR:	101287122(PYCARD)

DLE:	111182108(PYCARD)

PCAD:

102986634 102995954

PSIU:

116740165(PYCARD) 116740924

NASI:

112399310 112399406

ECB:

100063252

EPZ:

103547248

EAI:	106831881(PYCARD)

MYB:	102257170(PYCARD)

MYD:	102770333(PYCARD)

MMYO:

118656824(PYCARD)

MLF:	102438898(PYCARD)

MDT:	132232703(PYCARD)

PKL:

118704942

EFUS:

103296229(PYCARD)

MNA:	107540813(PYCARD)

DRO:	112304817(PYCARD) 112304871

SHON:

119001086 119001742(PYCARD)

AJM:	119036945 119038029(PYCARD) 119051385

PDIC:

114501650 114502872

PHAS:

123825584(PYCARD) 123825599

MMF:

118642512

PPAM:

129078013(PYCARD) 129078116

HAI:	109374176(PYCARD)

RFQ:	117019659(PYCARD)

PALE:

102888502(PYCARD)

PGIG:

120620052(PYCARD)

PVP:	105304504(PYCARD)

RAY:	107503994(PYCARD)

MJV:	108400691(PYCARD)

TOD:

119240170

SARA:

101546398(PYCARD)

SETR:

126030953(PYCARD)

LAV:	100664299(PYCARD)

TMU:

101357919

ETF:

101660779

DNM:	101413966(PYCARD)

MDO:

100016983

GAS:

123254678

SHR:	100925851(PYCARD) 105749479(PYDC1)

AFZ:

127561114

PCW:	110220452 110220572

TVP:

118830845

OAA:

100087358

NMEL:

110391096

SHAB:

115602746(PYCARD)

AROW:

112966225

ASN:

102373125

AMJ:	102563059(PYCARD) 106739173

PSS:	102459066 102460264 102462142

CMY:

102931493

CCAY:

125638280

DCC:	119856563 122460573

CPIC:

101934101 101949038 101950531 101951356 101953452 103306830

TST:	117876293 117876307 117877405

CABI:

116826846 116827464 116827477

MRV:	120395022 120395026 120395027 120403206 120403207 120403214 120404080

ACS:	103279569(pycard)

ASAO:

132779352

PVT:	110086383(PYCARD) 110086385

SUND:

121935506

PBI:	103066252 103066718

PMUR:

107296291 107296293 107297452 107297605

CTIG:

120302224 120302225

TSR:	106538133 106538147

PGUT:

117666820 117666879

APRI:

131196657 131198674

PTEX:

113452774(PYCARD)

NSS:	113422486(PYCARD)

VKO:	123032134(PYCARD)

PMUA:

114582857 114582859 114582861 114582865

PRAF:

128399784

ZVI:

118095381

HCG:

128331457

STOW:

125444315(PYCARD)

EMC:

129338874

XLA:	444817(pycard.L)

XTR:	100127742(pycard) 101732196

NPR:	108797733 108800545 108800546 108800547

RTEM:

120942587 120942588 120943042 120943045

BBUF:

121007991

BGAR:

122929327 122945548

MUO:	115474225(PYCARD)

GSH:

117360253

DRE:	57923(pycard)

SRX:	107737490 107737830 107749164(pycard)

SANH:

107660516(pycard) 107678967 107685954

SGH:	107575476 107592608

CCAR:

109061568(pycard) 109083915 109107753

CAUA:

113045413 113051882 113110513 113110529 113115898

CGIB:

127975504 128030189

PTET:

122360334

LROH:

127158261 127178988

OMC:	131522388(pycard)

PPRM:

120462223(pycard)

RKG:	130100672(pycard)

MAMB:

125242861

CIDE:

127496876

CERY:

137026659 137031788 137036098(pycard)

MASI:

127453494 127454630

TROS:

130557703(pycard)

TDW:	130432735 130433604

MANU:

129448546

IPU:

108278075

IFU:	128599894 128621531

PHYP:

113524807

TFD:	113652105(pycard)

TVC:	132840174(pycard)

TRN:

134300890

AMEX:

111188784(pycard) 111188786 125780425 125802086

EEE:

113569060

CHAR:

105891771(pycard) 105899550 116219384 116220678 122130213 122131378

TRU:

101076232

TFS:	130532868(pycard)

LCO:	104924727 109142120

NCC:	104949594 104961477

TBEN:

117476200 117476202 117476703 117497566 117500516

CGOB:

115021813

PGEO:

117460862

GACU:

117536338 117543206

ELY:	117260822 117265831(pycard)

EFO:	125893030(pycard)

PLEP:

121945774

SLUC:

116060125(pycard)

ECRA:

117946004

ESP:

116691564

PFLV:

114556912

GAT:	120811227 120811228

PPUG:

119197701 119197702

AFB:	129108984(pycard) 129108985

CLUM:

117728246(pycard) 117728247

PSWI:

130187974 130187975 130187982

MSAM:

119897169 119897170

SCHU:

122881738(pycard)

CUD:	121513102 121513717 121513979(caspa) 121514032

ALAT:

119005788

MZE:	101475740 112429886 112431240 112432183

ONL:	100693633 106096818 112848060

OAU:	116331548 116333498 120441128 120442327 120442502

OLA:	101161333 101161579 101170619

OML:	112136506 112136519(pycard) 112136687 112136702 112140172

CSAI:

133438568 133438586 133440450 133440453 133440648 133440649 133441137

XMA:	102235142(pycard) 111608209

XCO:	114141758(pycard) 114142066

XHE:	116715948(pycard) 116717317

PRET:

103477730 103477761

PFOR:

103154671 103154672 103154679(pycard) 107833470

PLAI:

106950221 106950226(pycard)

PMEI:

106920434 106920436(pycard)

GAF:	122831508(pycard)

PPRL:

129353537 129353540 129379991 129380035

CVG:	107081518 107081567

CTUL:

119798276(pycard)

GMU:	124866157(pycard)

NFU:	107379075(pycard)

KMR:	108229035(pycard)

ALIM:

106532613(pycard)

NWH:

119409641

AOCE:

111578016(pycard)

MCEP:

125017032

CSEM:

103388844(pycard)

POV:	109633374(pycard)

SSEN:

122762037(pycard)

HHIP:

117777220(pycard)

HSP:	118114033(pycard)

PPLT:

128449773(pycard)

SMAU:

118313138(pycard)

LCF:

108899584

SDU:

111233688

XGL:	120784018(pycard)

HCQ:

109512265

SBIA:

133501191(pycard)

PEE:

133402112

PTAO:

133479793

BPEC:

110161311(pycard)

BSPL:

114843270(pycard)

SJO:

128366072

SASA:

106568745 106573458 106573461 106573462(ASC) 106573513 106582385(ASC) 106605228(ASC)

STRU:

115156654 115177037 115177544

OTW:	112230319 112231018 112252437

OMY:	110488391 110516260 110521475 110523645 110530050 118940262

OGO:	123996758 124020676

ONE:	115114718 115142061

OKI:	109875105 109901473 109909364

OKE:	118364348 118367399

SALP:

111952641 111956329 111958533 112068609

SNH:	120031173 120047575 120053984 120055480

CCLU:

121563772 123484596

ELS:	105010143(pycard) 105024180

SFM:	108919109(pycard)

PKI:	111840044 111844200 111846294 111846447 111856855 111859606

AANG:

118223809(pycard) 118227695 118227697

LOC:	102686039 102686244

PSPA:

121298737 121306817 121328344

ARUT:

117399021 117433592 117964788 117968950

LCM:

102349920

LERI:

129695177

» show all

Reference

PMID:10567338

Authors

Masumoto J, Taniguchi S, Ayukawa K, Sarvotham H, Kishino T, Niikawa N, Hidaka E, Katsuyama T, Higuchi T, Sagara J

Title

ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells.

Journal

J Biol Chem 274:33835-8 (1999)
DOI:10.1074/jbc.274.48.33835

Sequence

[hsa:29108]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (24)   
   KEGG PATHWAY (24)   
Gene (506)   
   KEGG GENES (481)   
   KEGG MGENES (2)   
   RefGene (8)   
   OC (15)   
Literature (1)   
   PubMed (1)   
All databases (532)   

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