KEGG ORTHOLOGY: K12805

ORTHOLOGY: K12805

Entry

K12805                      KO

Symbol

NLRC4, CARD12

Name

NLR family CARD domain-containing protein 4

Pathway

map04621

NOD-like receptor signaling pathway

map05131

Shigellosis

map05132

Salmonella infection

map05134

Legionellosis

map05135

Yersinia infection

Disease

H01748

NLRC4 inflammasomopathy

H02159

Familial cold autoinflammatory syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
   05131 Shigellosis
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
   05135 Yersinia infection
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
   05134 Legionellosis
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
Pattern recognition receptors [BR:ko04054]
Cytoplasmic pattern recognition receptors
  NOD-like receptors
   K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4

Genes

HSA:	58484(NLRC4)

PTR:	459135(NLRC4)

PPS:	100977377(NLRC4)

GGO:	101140214(NLRC4)

PON:	100449353(NLRC4)

PPYG:

129030363(NLRC4)

NLE:	100595956(NLRC4)

HMH:	116480547(NLRC4)

SSYN:

129468239(NLRC4)

MCC:	706378(NLRC4)

MCF:	102142882(NLRC4)

MTHB:

126933890

MNI:	105479687(NLRC4)

CSAB:

103220528(NLRC4)

CATY:

105578400(NLRC4)

PANU:

100998325(NLRC4)

TGE:	112604823(NLRC4)

MLEU:

105542620(NLRC4)

RRO:	104681702(NLRC4)

RBB:	108528685(NLRC4)

TFN:	117062499(NLRC4)

PTEH:

111545415(NLRC4)

CANG:

105507497(NLRC4)

CSYR:

103274351(NLRC4)

OGA:	100941241(NLRC4)

MMU:	268973(Nlrc4)

MCAL:

110312299(Nlrc4)

MPAH:

110335928(Nlrc4)

RNO:	298784(Nlrc4)

MCOC:

116080207(Nlrc4)

ANU:	117717027(Nlrc4)

MUN:	110565106(Nlrc4)

CGE:	100765631(Nlrc4)

MAUA:

101827150(Nlrc4)

PROB:

127220126(Nlrc4)

PLEU:

114696038(Nlrc4)

MORG:

121432784(Nlrc4)

MFOT:

126514212

AAMP:

119807664(Nlrc4)

NGI:	103746764(Nlrc4)

HGL:	101712438(Nlrc4)

CPOC:

100735110(Nlrc4)

CCAN:

109699038(Nlrc4)

DORD:

105983561(Nlrc4)

DSP:	122122551(Nlrc4)

NCAR:

124963308

MMMA:

107137024(Nlrc4)

TUP:	102469158(NLRC4)

GVR:	103587627(NLRC4)

CFA:

102153882

VLG:	121491874(NLRC4)

NPO:	129510853(NLRC4)

AML:	100464785(NLRC4)

MPUF:

101687986(NLRC4)

MNP:	132022308(NLRC4)

MLK:	131808437(NLRC4)

NVS:	122915478(NLRC4)

ORO:	101376440(NLRC4)

EJU:	114219603(NLRC4)

ZCA:	113938384(NLRC4)

MLX:	118007513(NLRC4)

NSU:	110587476(NLRC4)

LWW:	102736143(NLRC4)

FCA:	101087657(NLRC4)

PYU:	121044321(NLRC4)

PCOO:

112864063(NLRC4)

PBG:	122497273(NLRC4)

PVIV:

125162349(NLRC4)

LRUF:

124503298

PTG:	102958929(NLRC4)

PPAD:

109266166(NLRC4)

PUC:

125937552

AJU:

106967889

HHV:	120244018(NLRC4)

BTA:	512480(NLRC4)

BOM:	102269253(NLRC4)

BIU:	109565964(NLRC4)

BBUB:

102405176(NLRC4)

BBIS:

104980943(NLRC4)

CHX:	102189315(NLRC4)

OAS:	101104138(NLRC4)

BTAX:

128055666(NLRC4)

ODA:	120851647(NLRC4)

CCAD:

122441540(NLRC4)

MBEZ:

129539869(NLRC4)

SSC:	100515078(NLRC4)

CFR:	102524619(NLRC4)

CBAI:

105078949(NLRC4)

CDK:	105095602(NLRC4)

VPC:	102537334(NLRC4)

BACU:

102998755(NLRC4)

BMUS:

118905780(NLRC4)

LVE:	103073097(NLRC4)

OOR:	101287377(NLRC4)

DLE:	111174903(NLRC4)

PCAD:

102980423(NLRC4)

PSIU:

116764186(NLRC4)

NASI:

112390988(NLRC4)

ECB:	100070605(NLRC4)

EPZ:	103567720(NLRC4)

EAI:	106839897(NLRC4)

MYB:	102240830(NLRC4)

MYD:	102755951(NLRC4)

MMYO:

118669122(NLRC4)

MLF:	102417417(NLRC4)

MDT:	132213489(NLRC4)

PKL:	118717129(NLRC4)

EFUS:

103305480(NLRC4)

MNA:	107541770(NLRC4)

DRO:	112297814(NLRC4)

SHON:

119001289(NLRC4)

AJM:	119050344(NLRC4)

PDIC:

114498723(NLRC4)

PHAS:

123811505(NLRC4)

MMF:	118630664(NLRC4)

PPAM:

129064472(NLRC4)

HAI:	109388792(NLRC4)

RFQ:	117032956(NLRC4)

PALE:

102886154(NLRC4)

PGIG:

120621795(NLRC4)

PVP:	105300072(NLRC4)

RAY:	107505750(NLRC4)

TOD:	119258666(NLRC4)

SARA:

101545252(NLRC4)

SETR:

126023804(NLRC4)

TMU:

101360631

ETF:	101662272(NLRC4)

DNM:	101446914(NLRC4)

TVP:	118842390(NLRC4)

CCRI:

104158670(NLRC4)

ACHC:

115350257(NLRC4)

HLE:	104840369(NLRC4)

GCL:

127014085

EGZ:	104124110(NLRC4)

NNI:	104018706(NLRC4)

PCRI:

104027013(NLRC4)

PADL:

103922882(NLRC4)

AFOR:

103902730(NLRC4)

GSTE:

104264272(NLRC4)

CLV:	102089994(NLRC4)

BREG:

104640928(NLRC4)

OHA:	104329304(NLRC4)

CVF:	104282352(NLRC4)

RTD:	128906647(NLRC4)

ASN:	102380000(NLRC4)

AMJ:	102561955(NLRC4)

CPOO:

109319884(NLRC4)

GGN:	109304829(NLRC4)

ACS:	100561094(nlrc4)

ASAO:

132761269(NLRC4)

SUND:

121919552(NLRC4)

PBI:	103057003(NLRC4)

PMUR:

107287479(NLRC4)

CTIG:

120312083(NLRC4)

TSR:	106544562(NLRC4)

PGUT:

117671880(NLRC4)

APRI:

131188758(NLRC4)

PTEX:

113433138(NLRC4)

NSS:	113420699(NLRC4)

VKO:	123035409(NLRC4)

HCG:	128348072(NLRC4)

GJA:	107122647(NLRC4)

EMC:	129324809(NLRC4)

XLA:	108716654(nlrc4.L)

XTR:	733844(nlrc4)

NPR:	108799665(NLRC4)

RTEM:

120937479(NLRC4)

BBUF:

120998780(NLRC4)

BGAR:

122936126(NLRC4)

MUO:	115465047(NLRC4)

GSH:	117357400(NLRC4)

LOC:	102696211(nlrc4)

PSPA:

121316731

ARUT:

117410620

PSEX:

120516641

LCM:	102362496(NLRC4)

RTP:

109939060

CPLA:

122552706

HOC:

132819694

BFO:	118422037 118422038

BBEL:

109462702 109465679 109470272 109475966 109475967 109477249 109480841 109486029

PJA:	122243016 122253146 122259637 122262188 122264619

PCHN:

125037889 125038262 125039943 125042692 125043724 125046887

HAME:

121855897 121862337 121876398

PTRU:

123514006 123517764

MYI:

110464041

PDAM:

113664313

SPIS:

111323814 111330322 111330325 111330347

» show all

Reference

PMID:11390368

Authors

Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES

Title

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1.

Journal

J Biol Chem 276:28309-13 (2001)
DOI:10.1074/jbc.C100250200

Sequence

[hsa:58484]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (10)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (275)   
   KEGG GENES (257)   
   KEGG MGENES (5)   
   RefGene (5)   
   OC (8)   
Literature (1)   
   PubMed (1)   
All databases (290)   

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