KEGG   ORTHOLOGY: K12909
Entry
K12909            Tight     KO                                     
Symbol
phpI
Name
carboxyvinyl-carboxyphosphonate phosphorylmutase [EC:2.7.8.23]
Pathway
map00440  Phosphonate and phosphinate metabolism
map01110  Biosynthesis of secondary metabolites
Reaction
R05165  1-carboxyvinyl carboxyphosphonate phosphorylmutase (decarboxylating)
R08868  1-carboxyvinyl carboxyphosphonate phosphorylmutase
R08869  carboxyphosphonopyruvate carboxy-lyase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K12909  phpI; carboxyvinyl-carboxyphosphonate phosphorylmutase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.8  Transferases for other substituted phosphate groups
    2.7.8.23  carboxyvinyl-carboxyphosphonate phosphorylmutase
     K12909  phpI; carboxyvinyl-carboxyphosphonate phosphorylmutase
Other DBs
COG: COG2513
GO: 0008807
Genes
AG: AAU00084(phpI) CAA48139(bcpA)
Reference
PMID:17632514
  Authors
Blodgett JA, Thomas PM, Li G, Velasquez JE, van der Donk WA, Kelleher NL, Metcalf WW
  Title
Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.
  Journal
Nat Chem Biol 3:480-5 (2007)
DOI:10.1038/nchembio.2007.9
  Sequence
[ag:AAU00084]
Reference
PMID:19489722
  Authors
Metcalf WW, van der Donk WA
  Title
Biosynthesis of phosphonic and phosphinic acid natural products.
  Journal
Annu Rev Biochem 78:65-94 (2009)
DOI:10.1146/annurev.biochem.78.091707.100215
Reference
PMID:1330557
  Authors
Pollack SJ, Freeman S, Pompliano DL, Knowles JR
  Title
Cloning, overexpression and mechanistic studies of carboxyphosphonoenolpyruvate mutase from Streptomyces hygroscopicus.
  Journal
Eur J Biochem 209:735-43 (1992)
DOI:10.1111/j.1432-1033.1992.tb17342.x
  Sequence
[ag:CAA48139]

  All links  
Ontology (4)   
   KEGG BRITE (2)   
   GO (1)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
   KEGG RCLASS (3)   
Gene (2)   
   KEGG GENES (2)   
Literature (3)   
   PubMed (3)   
All databases (20)   

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