KEGG   ORTHOLOGY: K12910
Entry
K12910            Tight     KO                                     
Symbol
pmmS
Name
2-phosphinomethylmalate synthase [EC:2.3.3.18]
Pathway
map00440  Phosphonate and phosphinate metabolism
map01110  Biosynthesis of secondary metabolites
Reaction
R08870  acetyl-CoA:phosphinopyruvate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K12910  pmmS; 2-phosphinomethylmalate synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.18  2-phosphinomethylmalate synthase
     K12910  pmmS; 2-phosphinomethylmalate synthase
Genes
AG: AAU00086(pms) BAA90528(pmmS)
Reference
  Authors
Metcalf WW, van der Donk WA
  Title
Biosynthesis of phosphonic and phosphinic acid natural products.
  Journal
Annu Rev Biochem 78:65-94 (2009)
DOI:10.1146/annurev.biochem.78.091707.100215
Reference
PMID:1368511
  Authors
Shimotohno KW, Imai S, Murakami T, Seto H
  Title
Purification and characterization of citrate synthase from Streptomyces hygroscopicus SF-1293 and comparison of its properties with those of 2-phosphinomethylmalic acid synthase.
  Journal
Agric Biol Chem 54:463-70 (1990)
DOI:10.1271/bbb1961.54.463
  Sequence

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