KEGG   ORTHOLOGY: K13039
Entry
K13039                      KO                                     

Name
comE
Definition
sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01240  Biosynthesis of cofactors
Module
M00358  Coenzyme M biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K13039  comE; sulfopyruvate decarboxylase subunit beta
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.79  sulfopyruvate decarboxylase
     K13039  comE; sulfopyruvate decarboxylase subunit beta
Other DBs
RN: R05774
COG: COG0028
GO: 0050545
Genes
GAI: IMCC3135_26025
SPLB: SFPGR_03630
SCL: sce7307
SCU: SCE1572_42560
MRM: A7982_08315
AVI: Avi_5427
RGR: FZ934_19570
MCH: Mchl_2070
MPO: Mpop_1237
RHZ: RHPLAN_13490
RUA: D1823_05120(comE)
JAN: Jann_1402
RDE: RD1_3813(bcpC)
RLI: RLO149_c006320(comE)
RPON: G3256_03850(comE)
PGD: Gal_02721
PHQ: D1820_16925(comE)
LEJ: ETW24_02300(comE)
LAQU: R2C4_00625(comE)
PTP: RCA23_c21890(comE)
SULZ: C1J03_11940(comE)
SULI: C1J05_06935(comE)
SEDI: EBB79_14300(comE)
THAS: C6Y53_06690(comE)
GOH: B932_3666
MAGX: XM1_0951
BSS: BSUW23_00990(rhiF)
KSK: KSE_22770
BLIN: BLSMQ_0785
ALO: CRK57522
FTJ: FTUN_1728
GBA: J421_0533
NDE: NIDE0733(comE)
NMV: NITMOv2_0602(comE)
NIO: NITINOP_0316(comE)
NJA: NSJP_1714(comE)
MMP: MMP1689(comE)
MMD: GYY_09305
MMAK: MMKA1_19230(comE)
MMAO: MMOS7_18040(comE)
MMAD: MMJJ_11400
MAE: Maeo_1219
MVO: Mvol_1271
METF: CFE53_02075(comE)
MTH: MTH_1207
MMG: MTBMA_c15850(comE)
METC: MTCT_1100
MWO: MWSIV6_1600(comE)
METE: tca_01164
METK: FVF72_05585(comE)
MTHM: FZP57_07670(comE)
MST: Msp_0277(comE)
MSI: Msm_0081
MEB: Abm4_0697(comE)
MMIL: sm9_0989(comE)
MEYE: TL18_05440
MOL: YLM1_0882
METH: MBMB1_1728(comE)
MFC: BRM9_0339(comE)
MFI: DSM1535_0959(comE)
MCUB: MCBB_2044(comE)
METT: CIT01_03905(comE)
METO: CIT02_09220(comE)
MFV: Mfer_0387
MKA: MK0393(comE)
MBU: Mbur_1459(comE)
MMET: MCMEM_1958
MMH: Mmah_1755
MPY: Mpsy_2150
MZI: HWN40_11480(comE)
MTP: Mthe_1624
MCJ: MCON_2821(comE)
MHI: Mhar_1121
MEMA: MMAB1_0060
NCT: NMSP_0154(comE)
LOKI: Lokiarch_08150(comE_1) Lokiarch_43600(comE_2)
PSYT: DSAG12_03865(comE_2)
 » show all
Reference
  Authors
Graupner M, Xu H, White RH
  Title
Identification of the gene encoding sulfopyruvate decarboxylase, an enzyme involved in biosynthesis of coenzyme M.
  Journal
J Bacteriol 182:4862-7 (2000)
DOI:10.1128/JB.182.17.4862-4867.2000
  Sequence
Reference
  Authors
Denger K, Mayer J, Buhmann M, Weinitschke S, Smits TH, Cook AM
  Title
Bifurcated degradative pathway of 3-sulfolactate in Roseovarius nubinhibens ISM via sulfoacetaldehyde acetyltransferase and (S)-cysteate sulfolyase.
  Journal
J Bacteriol 191:5648-56 (2009)
DOI:10.1128/JB.00569-09

KEGG   ORTHOLOGY: K06034
Entry
K06034                      KO                                     

Name
comD
Definition
sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01240  Biosynthesis of cofactors
Module
M00358  Coenzyme M biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K06034  comD; sulfopyruvate decarboxylase subunit alpha
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.79  sulfopyruvate decarboxylase
     K06034  comD; sulfopyruvate decarboxylase subunit alpha
Other DBs
RN: R05774
COG: COG4032
GO: 0050545
Genes
GAI: IMCC3135_26030
SPLB: SFPGR_03620
DHY: DESAM_21313
SCL: sce7306(comD)
SCU: SCE1572_42555
MRM: A7982_08316
AVI: Avi_5426
RGR: FZ934_19565
MCH: Mchl_2071
MPO: Mpop_1238
RUA: D1823_05115(comD)
JAN: Jann_1401
RDE: RD1_3812
RLI: RLO149_c006330(comD)
RPON: G3256_03855(comD)
PGD: Gal_02720
LEJ: ETW24_02305(comD)
LAQU: R2C4_00630(comD)
PTP: RCA23_c21900(comD)
SULI: C1J05_06930(comD)
SEDI: EBB79_14295(comD)
GOH: B932_3665
MAGX: XM1_0950
BSS: BSUW23_00985(rhiE)
KSK: KSE_22760
BLIN: BLSMQ_0784
ALO: CRK57521
GBA: J421_0534
NDE: NIDE0732(comD)
NMV: NITMOv2_0601(comD)
NIO: NITINOP_0317(comD)
NJA: NSJP_1713(comD)
MMP: MMP0411(comD)
MMD: GYY_02125
MMAK: MMKA1_04300(comD)
MMAO: MMOS7_04260(comD)
MMAD: MMJJ_06260
MAE: Maeo_1187
MVO: Mvol_1648
METF: CFE53_03745(comD)
MTH: MTH_1206
MMG: MTBMA_c15840(comD)
METC: MTCT_1099
MWO: MWSIV6_1599(comD)
METE: tca_01163
METK: FVF72_05590(comD)
MTHM: FZP57_07665(comD)
MST: Msp_0278(comD)
MSI: Msm_0080
MEB: Abm4_0698(comD)
MMIL: sm9_0990(comD)
MEYE: TL18_05435
MOL: YLM1_0881
METH: MBMB1_1727(comD)
MFC: BRM9_0340(comD)
MFI: DSM1535_0958(comD)
MCUB: MCBB_2039(comD)
METT: CIT01_03900(comD)
METO: CIT02_09225(comD)
MFV: Mfer_0388
MKA: MK0395(comD)
MBU: Mbur_1458(comD)
MMET: MCMEM_1957
MMH: Mmah_1754
MPY: Mpsy_2149
MZI: HWN40_11485(comD)
MTP: Mthe_1623
MCJ: MCON_2819(comD)
MHI: Mhar_1119
MEMA: MMAB1_0059
NCT: NMSP_0155(comD)
LOKI: Lokiarch_08160(comD_1) Lokiarch_43610(comD_2)
PSYT: DSAG12_03866(comD)
 » show all
Reference
  Authors
Graupner M, Xu H, White RH
  Title
Identification of the gene encoding sulfopyruvate decarboxylase, an enzyme involved in biosynthesis of coenzyme M.
  Journal
J Bacteriol 182:4862-7 (2000)
DOI:10.1128/JB.182.17.4862-4867.2000
Reference
  Authors
Denger K, Mayer J, Buhmann M, Weinitschke S, Smits TH, Cook AM
  Title
Bifurcated degradative pathway of 3-sulfolactate in Roseovarius nubinhibens ISM via sulfoacetaldehyde acetyltransferase and (S)-cysteate sulfolyase.
  Journal
J Bacteriol 191:5648-56 (2009)
DOI:10.1128/JB.00569-09

KEGG   ORTHOLOGY: K24393
Entry
K24393                      KO                                     

Name
comDE
Definition
sulfopyruvate decarboxylase [EC:4.1.1.79]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K24393  comDE; sulfopyruvate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.79  sulfopyruvate decarboxylase
     K24393  comDE; sulfopyruvate decarboxylase
Other DBs
RN: R05774
COG: COG4032 COG00028
GO: 0050545
Genes
FPL: Ferp_0997
GAC: GACE_0967
GAH: GAH_01908
MBA: Mbar_A3542
MBY: MSBRM_2300
MBW: MSBRW_1193
MBAR: MSBR2_0112
MBAK: MSBR3_0081
MAC: MA_3298(comDE)
MMA: MM_0134
MMAC: MSMAC_2536
METM: MSMTP_1159
MTHR: MSTHT_0113
MTHE: MSTHC_0615
MHOR: MSHOH_1389
MFZ: AOB57_001895(comE)
MHU: Mhun_2976
MLA: Mlab_0504
MPI: Mpet_0279
MBN: Mboo_2117
MPL: Mpal_2733
MPD: MCP_1993(comD_comE)
MEZ: Mtc_1467(comD_comE)
RCI: LRC441(comD)
 » show all
Reference
  Authors
Graham DE, Taylor SM, Wolf RZ, Namboori SC
  Title
Convergent evolution of coenzyme M biosynthesis in the Methanosarcinales: cysteate synthase evolved from an ancestral threonine synthase.
  Journal
Biochem J 424:467-78 (2009)
DOI:10.1042/BJ20090999
  Sequence
[mac:MA_3298]

KEGG   ENZYME: 4.1.1.79
Entry
EC 4.1.1.79                 Enzyme                                 

Name
sulfopyruvate decarboxylase;
sulfopyruvate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
3-sulfopyruvate carboxy-lyase (2-sulfoacetaldehyde-forming)
Reaction(IUBMB)
3-sulfopyruvate = 2-sulfoacetaldehyde + CO2 [RN:R05774]
Reaction(KEGG)
R05774
Substrate
3-sulfopyruvate [CPD:C05528]
Product
2-sulfoacetaldehyde [CPD:C00593];
CO2 [CPD:C00011]
Comment
Requires thiamine diphosphate. Does not decarboxylate pyruvate or phosphonopyruvate. The enzyme appears to be oxygen-sensitive.
History
EC 4.1.1.79 created 2002
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K06034  sulfopyruvate decarboxylase subunit alpha
K13039  sulfopyruvate decarboxylase subunit beta
K24393  sulfopyruvate decarboxylase
Genes
GAI: IMCC3135_26025 IMCC3135_26030
SPLB: SFPGR_03620 SFPGR_03630
DHY: DESAM_21313
SCL: sce7306(comD) sce7307
SCU: SCE1572_42555 SCE1572_42560
MRM: A7982_08315 A7982_08316
AVI: Avi_5426 Avi_5427
RGR: FZ934_19565 FZ934_19570
MCH: Mchl_2070 Mchl_2071
MPO: Mpop_1237 Mpop_1238
RUA: D1823_05115(comD) D1823_05120(comE)
RDE: RD1_3812 RD1_3813(bcpC)
RLI: RLO149_c006320(comE) RLO149_c006330(comD)
RPON: G3256_03850(comE) G3256_03855(comD)
LEJ: ETW24_02300(comE) ETW24_02305(comD)
LAQU: R2C4_00625(comE) R2C4_00630(comD)
PTP: RCA23_c21890(comE) RCA23_c21900(comD)
SULI: C1J05_06930(comD) C1J05_06935(comE)
SEDI: EBB79_14295(comD) EBB79_14300(comE)
BSS: BSUW23_00985(rhiE) BSUW23_00990(rhiF)
FTJ: FTUN_1728
NDE: NIDE0732(comD) NIDE0733(comE)
NMV: NITMOv2_0601(comD) NITMOv2_0602(comE)
NIO: NITINOP_0316(comE) NITINOP_0317(comD)
NJA: NSJP_1713(comD) NSJP_1714(comE)
MMP: MMP0411(comD) MMP1689(comE)
MMAK: MMKA1_04300(comD) MMKA1_19230(comE)
MMAO: MMOS7_04260(comD) MMOS7_18040(comE)
METF: CFE53_02075(comE) CFE53_03745(comD)
MMG: MTBMA_c15840(comD) MTBMA_c15850(comE)
MWO: MWSIV6_1599(comD) MWSIV6_1600(comE)
METK: FVF72_05585(comE) FVF72_05590(comD)
MTHM: FZP57_07665(comD) FZP57_07670(comE)
MST: Msp_0277(comE) Msp_0278(comD)
MEB: Abm4_0697(comE) Abm4_0698(comD)
MMIL: sm9_0989(comE) sm9_0990(comD)
METH: MBMB1_1727(comD) MBMB1_1728(comE)
MFC: BRM9_0339(comE) BRM9_0340(comD)
MFI: DSM1535_0958(comD) DSM1535_0959(comE)
MCUB: MCBB_2039(comD) MCBB_2044(comE)
METT: CIT01_03900(comD) CIT01_03905(comE)
METO: CIT02_09220(comE) CIT02_09225(comD)
MKA: MK0393(comE) MK0395(comD)
FPL: Ferp_0997
GAC: GACE_0967
GAH: GAH_01908
MBAR: MSBR2_0112
MBAK: MSBR3_0081
MAC: MA_3298(comDE)
MMA: MM_0134
MMAC: MSMAC_2536
METM: MSMTP_1159
MTHR: MSTHT_0113
MTHE: MSTHC_0615
MHOR: MSHOH_1389
MFZ: AOB57_001895(comE)
MBU: Mbur_1458(comD) Mbur_1459(comE)
MZI: HWN40_11480(comE) HWN40_11485(comD)
MCJ: MCON_2819(comD) MCON_2821(comE)
MHU: Mhun_2976
MLA: Mlab_0504
MPI: Mpet_0279
MBN: Mboo_2117
MPL: Mpal_2733
MPD: MCP_1993(comD_comE)
MEZ: Mtc_1467(comD_comE)
RCI: LRC441(comD)
NCT: NMSP_0154(comE) NMSP_0155(comD)
LOKI: Lokiarch_08150(comE_1) Lokiarch_08160(comD_1) Lokiarch_43600(comE_2) Lokiarch_43610(comD_2)
PSYT: DSAG12_03865(comE_2) DSAG12_03866(comD)
 » show all
Reference
1  [PMID:10940029]
  Authors
Graupner M, Xu H, White RH
  Title
Identification of the gene encoding sulfopyruvate decarboxylase, an enzyme involved in biosynthesis of coenzyme M.
  Journal
J Bacteriol 182:4862-7 (2000)
DOI:10.1128/JB.182.17.4862-4867.2000
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.79
IUBMB Enzyme Nomenclature: 4.1.1.79
ExPASy - ENZYME nomenclature database: 4.1.1.79
BRENDA, the Enzyme Database: 4.1.1.79
CAS: 303155-97-7

KEGG   REACTION: R05774
Entry
R05774                      Reaction                               

Name
sulfopyruvate carboxy-lyase
Definition
3-Sulfopyruvate <=> Sulfoacetaldehyde + CO2
Equation
Comment
Requires thiamine diphosphate
Reaction class
RC00506  C00593_C05528
Enzyme
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Module
M00358  Coenzyme M biosynthesis
Orthology
K06034  sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79]
K13039  sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79]
K24393  sulfopyruvate decarboxylase [EC:4.1.1.79]
Other DBs
RHEA: 20951

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