KEGG   ORTHOLOGY: K13232
Entry
K13232                      KO                                     

Name
ST
Definition
stilbene synthase [EC:2.3.1.95]
Pathway
ko00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
    K13232  ST; stilbene synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K13232  ST; stilbene synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.95  trihydroxystilbene synthase
     K13232  ST; stilbene synthase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Type III PKS
   Plant type
    K13232  ST; stilbene synthase
Other DBs
RN: R01614
GO: 0050350
Genes
VVI: 100217471(STS) 100242994(STS) 100256566(VINST1) 100853406(RS) 100853675 104877274

KEGG   ENZYME: 2.3.1.95
Entry
EC 2.3.1.95                 Enzyme                                 

Name
trihydroxystilbene synthase;
resveratrol synthase;
stilbene synthase (ambiguous)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Reaction(IUBMB)
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + trans-resveratrol + 4 CO2 [RN:R01614]
Reaction(KEGG)
R01614
Substrate
malonyl-CoA [CPD:C00083];
4-coumaroyl-CoA [CPD:C00223]
Product
CoA [CPD:C00010];
trans-resveratrol [CPD:C03582];
CO2 [CPD:C00011]
Comment
Not identical with EC 2.3.1.74 naringenin-chalcone synthase or EC 2.3.1.146 pinosylvin synthase.
History
EC 2.3.1.95 created 1989
Pathway
ec00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K13232  stilbene synthase
Genes
VVI: 100217471(STS) 100242994(STS) 100256566(VINST1) 100853406(RS) 100853675 104877274
Reference
1  [PMID:6427224]
  Authors
Schoppner A, Kindl H.
  Title
Purification and properties of a stilbene synthase from induced cell suspension cultures of peanut.
  Journal
J Biol Chem 259:6806-11 (1984)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.95
IUBMB Enzyme Nomenclature: 2.3.1.95
ExPASy - ENZYME nomenclature database: 2.3.1.95
BRENDA, the Enzyme Database: 2.3.1.95
CAS: 128449-70-7

KEGG   REACTION: R01614
Entry
R01614                      Reaction                               

Name
Malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Definition
3 Malonyl-CoA + p-Coumaroyl-CoA <=> 4 CoA + Resveratrol + 4 CO2
Equation
3 C00083 + C00223 <=> 4 C00010 + C03582 + 4 C00011
Comment
multi-step reaction
Reaction class
RC00004  C00010_C00083  C00010_C00223
RC02855  C00223_C03582
Enzyme
Pathway
rn00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K13232  stilbene synthase [EC:2.3.1.95]
Other DBs
RHEA: 11939

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