KEGG   ORTHOLOGY: K13279
Entry
K13279                      KO                                     

Name
PRDX1
Definition
peroxiredoxin 1 [EC:1.11.1.24]
Pathway
ko04146  Peroxisome
ko05146  Amoebiasis
Disease
H02221  Methylmalonic aciduria and homocystinuria
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    K13279  PRDX1; peroxiredoxin 1
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K13279  PRDX1; peroxiredoxin 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K13279  PRDX1; peroxiredoxin 1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.24  thioredoxin-dependent peroxiredoxin
     K13279  PRDX1; peroxiredoxin 1
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K13279  PRDX1; peroxiredoxin 1
Other DBs
GO: 0008379
Genes
HSA: 5052(PRDX1)
PTR: 456537(PRDX1)
PPS: 100994710(PRDX1)
GGO: 101153165(PRDX1)
PON: 100455467(PRDX1)
NLE: 100607562(PRDX1)
MCC: 706142(PRDX1)
MCF: 101867473(PRDX1)
CSAB: 103224911(PRDX1)
RRO: 104662136(PRDX1)
RBB: 108535650(PRDX1)
CJC: 100399691(PRDX1)
SBQ: 101028711
MMU: 18477(Prdx1)
MCAL: 110293023(Prdx1)
MPAH: 110322921(Prdx1)
RNO: 117254(Prdx1)
MUN: 110546546(Prdx1)
NGI: 103737784(Prdx1)
HGL: 101709755(Prdx1)
CCAN: 109686604
OCU: 100347160(PRDX1)
TUP: 102473833(PRDX1)
CFA: 475375(PRDX1)
VVP: 112914962(PRDX1)
AML: 100466243(PRDX1)
UMR: 103670775(PRDX1)
UAH: 113254744(PRDX1)
ORO: 101378742(PRDX1)
ELK: 111142963
FCA: 101091216(PRDX1)
PTG: 102951072 102953941(PRDX1)
PPAD: 109266973(PRDX1)
AJU: 106970246(PRDX1)
BTA: 281997(PRDX1)
BOM: 102277875(PRDX1)
BIU: 109556354(PRDX1)
BBUB: 102400947(PRDX1)
CHX: 102183385(PRDX1)
OAS: 101120966(PRDX1)
SSC: 100512476(PRDX1)
CFR: 102508982(PRDX1)
CDK: 105090869(PRDX1)
LVE: 103075971(PRDX1)
OOR: 101274985(PRDX1)
DLE: 111175750(PRDX1)
PCAD: 102979500(PRDX1) 112064227
ECB: 100052421(PRDX1)
EPZ: 103544684 103551878(PRDX1)
EAI: 106826140(PRDX1)
MYB: 102261140(PRDX1)
MYD: 102764098(PRDX1)
MNA: 107526720(PRDX1)
HAI: 109375512(PRDX1) 109391623
DRO: 112309363 112314613(PRDX1)
PALE: 102889097(PRDX1)
RAY: 107501300 107506892(PRDX1)
MJV: 108385734(PRDX1)
LAV: 100673794(PRDX1)
TMU: 101352766
MDO: 100013335(PRDX1)
SHR: 100914302(PRDX1)
PCW: 110209281(PRDX1)
OAA: 100076481(PRDX1)
GGA: 424598(PRDX1)
MGP: 100547686(PRDX1)
CJO: 107317443(PRDX1)
NMEL: 110402953(PRDX1)
APLA: 101804206(PRDX1)
ACYG: 106033095(PRDX1)
TGU: 100190347(PRDX1)
LSR: 110469638(PRDX1)
SCAN: 103814981(PRDX1)
GFR: 102038670(PRDX1)
FAB: 101814884(PRDX1)
PHI: 102110826(PRDX1)
PMAJ: 107208009(PRDX1)
CCAE: 111933111(PRDX1)
CCW: 104695242(PRDX1)
ETL: 114062131(PRDX1)
FPG: 101914456(PRDX1)
FCH: 102058204(PRDX1)
CLV: 102086282(PRDX1)
EGZ: 104126261(PRDX1)
NNI: 104015415(PRDX1)
ACUN: 113482956(PRDX1)
PADL: 103919134(PRDX1)
AAM: 106485926(PRDX1)
ASN: 102382350(PRDX1)
AMJ: 102560699(PRDX1)
PSS: 102453576(PRDX1)
CMY: 102932659(PRDX1)
CPIC: 101951902(PRDX1)
ACS: 100558538(prdx1)
PVT: 110073750(PRDX1) 110082647
PBI: 103060922(PRDX1)
PMUR: 107283430(PRDX1)
TSR: 106546848(PRDX1)
PMUA: 114599095(PRDX1)
GJA: 107107907(PRDX1)
XLA: 432262 443911(prdx1.S)
XTR: 496551(prdx1)
NPR: 108800337(PRDX1)
DRE: 541344(prdx1) 791455(prdx2)
IPU: 108258897(prdx2) 108267618(NKEF)
PHYP: 113537587(prdx2) 113540103
EEE: 113570157
TRU: 101065832(prdx2) 101068780
MZE: 101477314(prdx2) 101480156
OLA: 101170008(prdx2) 101175597
XMA: 102221624 102237158(prdx2)
XCO: 114144526(prdx2) 114145926
PRET: 103464517(prdx2) 103479005
CVG: 107083617 107096609(prdx2)
NFU: 107384409 107393158(prdx2)
KMR: 108236277(prdx2) 108238211
CSEM: 103384203(prdx2) 103395823
POV: 109627601(prdx2) 109647605
SASA: 100195794(prdx1) 100196357(tdx) 106564567(prdx1) 106600402
ELS: 105012170 105021922(prdx1)
LCM: 102356586(PRDX1)
CMK: 103182772(prdx1) 103187586(prdx2)
BFO: 118431924
CIN: 493870(per-like)
SPU: 581408
APLC: 110989628
SKO: 100372514
DME: Dmel_CG1633(Jafrac1) Dmel_CG6888(CG6888)
DSI: Dsimw501_GD14531(Dsim_GD14531) Dsimw501_GD17115(Dsim_GD17115)
DYA: Dyak_GE17062(Dyak_Jafrac1) Dyak_GE22230
DAZ: 108619105
MDE: 101887644
LCQ: 111678965
AGA: AgaP_AGAP011054(TPX2)
AAG: 5564117
AME: 409954
CCAL: 108628189
OBB: 114879015
SOC: 105201440
MPHA: 105831335
AEC: 105149769
ACEP: 105621996
PBAR: 105429094
VEM: 105565298
HST: 105186023
DQU: 106744209
CFO: 105253804
LHU: 105671713
PGC: 109863827
OBO: 105277708
PCF: 106789319
NVI: 100116729
CSOL: 105368123
MDL: 103570189
DPA: 109546524
BMOR: 692638(Jafrac1)
BMAN: 114247212
PMAC: 106719727
PRAP: 110994015
HAW: 110377656
TNL: 113493007
API: 100161272
DNX: 107168705
AGS: 114130266
RMD: 113560245
BTAB: 109042078
CLEC: 106669365
ZNE: 110839321
FCD: 110856739
PVM: 113814492
TUT: 107362540
DPTE: 113794409
CEL: CELE_F09E5.15(prdx-2)
CBR: CBG25150
PCAN: 112573157
MYI: 110456587
OBI: 106872407
LAK: 106165078
EHI: EHI_001420(294.t00003) EHI_061980(442.t00004) EHI_114010(298.t00001) EHI_122310(94.t00032) EHI_123390 EHI_139570 EHI_145840(828.t00001) EHI_201250(136.t00007)
 » show all
Reference
  Authors
Yan Y, Sabharwal P, Rao M, Sockanathan S
  Title
The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox-dependent activation of GDE2.
  Journal
Cell 138:1209-21 (2009)
DOI:10.1016/j.cell.2009.06.042
  Sequence
[hsa:5052]
Reference
PMID:9497357
  Authors
Kang SW, Chae HZ, Seo MS, Kim K, Baines IC, Rhee SG
  Title
Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha.
  Journal
J Biol Chem 273:6297-302 (1998)
DOI:10.1074/jbc.273.11.6297
  Sequence
[hsa:5052]

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