KEGG   ORTHOLOGY: K13320
Entry
K13320            Tight     KO                                     
Symbol
oleY
Name
L-olivosyl-oleandolide 3-O-methyltransferase [EC:2.1.1.239]
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00775  Oleandomycin biosynthesis, malonyl-CoA + methylmalonyl-CoA => 8,8a-deoxyoleandolide => oleandomycin
Reaction
R06456  S-adenosyl-L-methionine:L-olivosyl-oleandolide B 3-O-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K13320  oleY; L-olivosyl-oleandolide 3-O-methyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K13320  oleY; L-olivosyl-oleandolide 3-O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.239  L-olivosyl-oleandolide 3-O-methyltransferase
     K13320  oleY; L-olivosyl-oleandolide 3-O-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Methylase
   K13320  oleY; L-olivosyl-oleandolide 3-O-methyltransferase
Genes
AG: CAA05644(oleY)
Reference
PMID:9749673
  Authors
Olano C, Rodriguez AM, Michel JM, Mendez C, Raynal MC, Salas JA
  Title
Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.
  Journal
Mol Gen Genet 259:299-308 (1998)
DOI:10.1007/s004380050816
  Sequence
[ag:CAA05644]
Reference
PMID:11514520
  Authors
Rodriguez L, Rodriguez D, Olano C, Brana AF, Mendez C, Salas JA
  Title
Functional analysis of OleY L-oleandrosyl 3-O-methyltransferase of the oleandomycin biosynthetic pathway in Streptomyces antibioticus.
  Journal
J Bacteriol 183:5358-63 (2001)
DOI:10.1128/JB.183.18.5358-5363.2001

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (1)   
   KEGG GENES (1)   
Literature (2)   
   PubMed (2)   
All databases (17)   

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