KEGG ORTHOLOGY: K13370

ORTHOLOGY: K13370

Entry

K13370                      KO

Symbol

HSD17B8

Name

17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]

Pathway

map00061

Fatty acid biosynthesis

map00140

Steroid hormone biosynthesis

map01100

Metabolic pathways

map01212

Fatty acid metabolism

Module

M00873

Fatty acid biosynthesis in mitochondria, animals

M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

Reaction

R01836

testosterone:NAD+ 17-oxidoreductase

R02352

estradiol-17beta:NAD+ 17-oxidoreductase

R02353

estradiol-17beta:NADP+ 17-oxidoreductase

R04681

estriol:NAD+ 17-oxidoreductase

R04682

estriol:NADP+ 17-oxidoreductase

R08945

11beta,17beta-dihydroxy-4-androsten-3-one:NAD+ 17-oxidoreductase

R08980

11beta,17beta-dihydroxy-4-androsten-3-one:NADP+ 17-oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K13370  HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit
   00140 Steroid hormone biosynthesis
    K13370  HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     K13370  HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     K13370  HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit

Other DBs

GO:	0004303 0047035

Genes

HSA:	7923(HSD17B8)

PTR:	746685(HSD17B8)

PPS:	100993294(HSD17B8)

GGO:	101143846(HSD17B8)

PON:	100461538(HSD17B8)

PPYG:

129038164(HSD17B8)

NLE:	100607728(HSD17B8)

HMH:	116460448(HSD17B8)

SSYN:

129473011(HSD17B8)

MCC:	718119(HSD17B8)

MCF:	102134563(HSD17B8)

MTHB:

126952791

MNI:	105474440(HSD17B8)

CSAB:

103221677(HSD17B8)

CATY:

105593548(HSD17B8)

PANU:

100999420(HSD17B8)

TGE:	112622112(HSD17B8)

MLEU:

105537159(HSD17B8)

RRO:	104657981(HSD17B8)

RBB:	108540288(HSD17B8)

TFN:	117087034(HSD17B8)

PTEH:

111542910(HSD17B8)

CANG:

105514238(HSD17B8)

CJC:	100415565(HSD17B8)

SBQ:	101042328(HSD17B8)

CIMI:

108300062(HSD17B8)

ANAN:

105723573(HSD17B8)

CSYR:

103262638(HSD17B8)

MMUR:

105886007(HSD17B8)

LCAT:

123631820(HSD17B8)

PCOQ:

105821671(HSD17B8)

OGA:	100962777(HSD17B8)

MMU:	14979(Hsd17b8)

MCAL:

110283634(Hsd17b8)

MPAH:

110335682(Hsd17b8)

RNO:	361802(Hsd17b8)

MCOC:

116074258(Hsd17b8)

ANU:	117702284 117724490(Hsd17b8)

MUN:	110543418(Hsd17b8)

CGE:	100766230(Hsd17b8)

MAUA:

101822987(Hsd17b8)

PROB:

127224267(Hsd17b8)

PLEU:

114686356(Hsd17b8)

MORG:

121435293(Hsd17b8)

MFOT:

126499757

AAMP:

119822751(Hsd17b8)

NGI:	103739734(Hsd17b8)

HGL:	101726130(Hsd17b8)

CPOC:

100736228(Hsd17b8)

CCAN:

109686670(Hsd17b8)

DORD:

105999876(Hsd17b8)

DSP:	122111098(Hsd17b8)

PLOP:

125352714(Hsd17b8)

NCAR:

124988825

MMMA:

107143797(Hsd17b8)

OCU:

100353430

OPI:	101534396(HSD17B8)

TUP:	102494154(HSD17B8)

GVR:	103597939(HSD17B8)

CFA:	607895(HSD17B8)

CLUD:

112641399(HSD17B8)

VVP:	112913875(HSD17B8)

VLG:	121498363(HSD17B8)

NPO:	129512545(HSD17B8)

AML:	100475452(HSD17B8)

UMR:	103665501(HSD17B8)

UAH:	113243793(HSD17B8)

UAR:	123790935(HSD17B8)

ELK:

111152286

LLV:

125102138

MPUF:

101678329(HSD17B8)

MNP:	132017870(HSD17B8)

MLK:	131834262(HSD17B8)

NVS:	122911050(HSD17B8)

ORO:	101374521(HSD17B8)

EJU:	114222161(HSD17B8)

ZCA:	113926431(HSD17B8)

MLX:	118001624(HSD17B8)

NSU:	110575572(HSD17B8)

LWW:	102727323(HSD17B8)

FCA:	101086309(HSD17B8)

PYU:	121029274(HSD17B8)

PCOO:

112862188(HSD17B8)

PBG:	122489390(HSD17B8)

PVIV:

125165813(HSD17B8)

LRUF:

124528139

PTG:	102968797(HSD17B8)

PPAD:

109271428(HSD17B8)

PUC:

125938379

AJU:

106976117

HHV:	120238155(HSD17B8)

BTA:	532422(HSD17B8)

BOM:	102286352(HSD17B8)

BIU:	109576549(HSD17B8)

BBIS:

104994894(HSD17B8)

CHX:	102189913(HSD17B8)

OAS:	101116612(HSD17B8)

BTAX:

128055540(HSD17B8)

ODA:	120869852(HSD17B8)

CCAD:

122429970(HSD17B8)

MBEZ:

129543409(HSD17B8)

SSC:	100154372(HSD17B8)

CFR:	102504651(HSD17B8)

CBAI:

105064231(HSD17B8)

CDK:	105101392(HSD17B8)

VPC:	102531684(HSD17B8)

BACU:

103006419(HSD17B8)

BMUS:

118903690(HSD17B8)

LVE:	103088201(HSD17B8)

OOR:	101287044(HSD17B8)

DLE:	111178672(HSD17B8)

PCAD:

102973624(HSD17B8)

PSIU:

116761747(HSD17B8)

NASI:

112413939(HSD17B8)

ECB:	100061414(HSD17B8)

EPZ:	103541177(HSD17B8)

EAI:	106834606(HSD17B8)

MYB:	102252900(HSD17B8)

MYD:	102766664(HSD17B8)

MMYO:

118679524(HSD17B8)

MLF:	102441694(HSD17B8)

MDT:	132237483(HSD17B8)

PKL:	118705664(HSD17B8)

EFUS:

103303029(HSD17B8)

MNA:	107542679(HSD17B8)

DRO:	112302215(HSD17B8)

SHON:

118991479(HSD17B8)

AJM:	119041212(HSD17B8) 119043050

PDIC:

114495472(HSD17B8)

PHAS:

123815837(HSD17B8)

MMF:	118621536(HSD17B8)

PPAM:

129067374(HSD17B8)

HAI:	109392392(HSD17B8)

RFQ:	117018515(HSD17B8)

PALE:

102889883(HSD17B8)

PGIG:

120597660(HSD17B8)

PVP:	105300978(HSD17B8)

RAY:	107511987(HSD17B8)

MJV:	108396325(HSD17B8)

TOD:	119252330(HSD17B8)

SARA:

101542173(HSD17B8)

SETR:

125995693(HSD17B8)

LAV:	104847005(HSD17B8)

TMU:

101349761

ETF:	101652958(HSD17B8)

DNM:	101413097(HSD17B8)

MDO:	100025234(HSD17B8)

GAS:	123245239(HSD17B8)

SHR:	100914913(HSD17B8)

AFZ:

127561130

PCW:	110199337(HSD17B8)

TVP:	118856108(HSD17B8)

ETL:	114073640(HSD17B8)

AGEN:

126034979

RTD:	128901681(HSD17B8)

AMJ:	106737258(HSD17B8)

CPOO:

109314002(HSD17B8)

CMY:	102929636(HSD17B8)

CCAY:

125621410(HSD17B8)

DCC:	119842600(HSD17B8)

CPIC:

101936532(HSD17B8)

CABI:

116829514(HSD17B8)

MRV:	120394890(HSD17B8)

ACS:	103281981(hsd17b8)

ASAO:

132766321(HSD17B8)

PVT:	110091148(HSD17B8)

SUND:

121922616(HSD17B8)

PMUR:

107298989(HSD17B8)

CTIG:

120318407(HSD17B8)

PGUT:

117673479(HSD17B8)

APRI:

131192799(HSD17B8)

NSS:

113431000

VKO:	123021082(HSD17B8)

PMUA:

114592619(HSD17B8)

PRAF:

128408710(HSD17B8)

ZVI:	118081373(HSD17B8)

HCG:	128348038(HSD17B8)

GJA:	107112070(HSD17B8)

STOW:

125428831(HSD17B8)

EMC:	129326927(HSD17B8)

XLA:	108700217(hsd17b8.S)

XTR:	549425(hsd17b8)

NPR:	108788379(HSD17B8)

RTEM:

120914319(HSD17B8)

BBUF:

121009488(HSD17B8)

BGAR:

122946589(HSD17B8)

MUO:	115466154(HSD17B8)

GSH:	117349511(HSD17B8)

DRE:	64815(hsd17b8)

SRX:	107729869 107751687

SANH:

107694093(hsd17b8) 107694751

SGH:	107575377(hsd17b8)

CCAR:

109111239(hsd17b8)

CAUA:

113062607(hsd17b8)

CGIB:

127935752

PTET:

122335304(hsd17b8)

LROH:

127181953(hsd17b8)

OMC:	131526069(hsd17b8)

PPRM:

120483608(hsd17b8)

RKG:	130102356(hsd17b8)

MAMB:

125275699(hsd17b8)

CIDE:

127500660 127501449

CERY:

137037830(hsd17b8)

MASI:

127425636

TROS:

130567213(hsd17b8)

TDW:	130415742(hsd17b8)

AMEX:

103023719(hsd17b8)

CMAO:

118805912(hsd17b8)

EEE:	113591822(hsd17b8)

CHAR:

105909036(hsd17b8)

TRU:	101066298(hsd17b8)

TFS:	130518460(hsd17b8)

TNG:	GSTEN00033718G001

LCO:	104933390(hsd17b8)

NCC:	104947942 104963938(hsd17b8)

TBEN:

117477505(hsd17b8)

CGOB:

115015684(hsd17b8)

PGEO:

117455210(hsd17b8)

GACU:

117535278(hsd17b8)

EMAC:

134874480(hsd17b8)

ELY:	117263188(hsd17b8)

EFO:	125905292(hsd17b8)

PLEP:

121958033(hsd17b8)

SLUC:

116047056(hsd17b8)

ECRA:

117956856(hsd17b8)

ESP:	116701176(hsd17b8)

PFLV:

114568207(hsd17b8)

GAT:	120826885(hsd17b8)

PPUG:

119219380(hsd17b8)

AFB:	129097384(hsd17b8)

CLUM:

117739597(hsd17b8)

PSWI:

130193665(hsd17b8)

MSAM:

119907868(hsd17b8)

SCHU:

122864403(hsd17b8)

CUD:	121524093(hsd17b8)

ALAT:

119014652(hsd17b8)

MZE:	101480373(hsd17b8)

ONL:	100534581(hsd17b8)

OAU:	116310837(hsd17b8)

OLA:	101165741(hsd17b8)

OML:	112161804(hsd17b8)

CSAI:

133460688(hsd17b8)

XMA:

102218211

XCO:

114156484

XHE:	116730568(hsd17b8)

PRET:

103472946

PFOR:

103146399(hsd17b8)

PLAI:

106962920(hsd17b8)

PMEI:

106934275(hsd17b8)

GAF:	122843209 122844001

PPRL:

129375883(hsd17b8)

CVG:	107103718(hsd17b8)

CTUL:

119795054(hsd17b8)

GMU:	124878952(hsd17b8)

NFU:

107392413

KMR:	108242645(hsd17b8)

ALIM:

106519579(hsd17b8)

NWH:	119425569(hsd17b8)

AOCE:

111584591(hsd17b8)

MCEP:

125019674(hsd17b8)

CSEM:

103393879(hsd17b8)

POV:	109642706(hsd17b8)

SSEN:

122761147(hsd17b8)

HHIP:

117770994(hsd17b8)

HSP:	118124653(hsd17b8)

PPLT:

128462067(hsd17b8)

SMAU:

118292343(hsd17b8)

LCF:	108872786 108888416

SDU:	111239433(hsd17b8)

SLAL:

111661174(hsd17b8)

XGL:	120786769(hsd17b8)

SSCV:

125987277

SBIA:

133500347(hsd17b8)

PEE:	133396097(hsd17b8)

PTAO:

133471304(hsd17b8)

BPEC:

110173336(hsd17b8)

MALB:

109952509(hsd17b8)

BSPL:

114866168(hsd17b8)

SJO:	128374438(hsd17b8)

SASA:

106569955(hsd17b8)

STRU:

115175912(hsd17b8)

OTW:	112229803(hsd17b8)

OMY:	110488343(hsd17b8)

OGO:	124043531(hsd17b8)

ONE:	115131608(hsd17b8)

OKI:	109903602(hsd17b8)

OKE:

118398183

SALP:

111954981(hsd17b8)

SNH:	120027350(hsd17b8)

CCLU:

121571584(hsd17b8)

ELS:	105005658(hsd17b8)

SFM:	108935620(hsd17b8)

PKI:	111835643(hsd17b8)

AANG:

118232975(hsd17b8)

PSPA:

121298829(hsd17b8)

PSEX:

120539120(hsd17b8)

LCM:	102361445(HSD17B8)

HOC:	132832492(hsd17b8)

LERI:

129694466(hsd17b8)

PMRN:

116955396(HSD17B8)

BFO:	118418417 118420782 118422026 118428506 118428697

BBEL:

109462023 109466148 109480466 109483393 109483394 109483416 109483936

CIN:

SPU:

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG3603(CG3603)

DER:

6550324

DSE:

6616216

DSI:	Dsimw501_GD16628(Dsim_GD16628)

DYA:	Dyak_GE16292

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11166

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108378376 108378742

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

121595979 121602781 121603184 121603341

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ001771

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:	105202077 113006118

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:	105250631 105253158 105253416 105253424 105253428 105253434 105253522 105253528 105259480 105259485 105259506 109610597 112638186

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

NVI:

CSOL:

TPRE:

LHT:

LBD:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:	108914329 108917119

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_213161

BANY:

112051479

MJU:

123881318

NIQ:

126777642

VCD:	124536323 124536339

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:	119830277 119830278

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:	103517555 103517556

CLEC:

106662223

HHAL:

106681696

HVI:	124365275 124365849 124365886 124366282 124366283 124366284 124366285 124366287 124366435 124366535 124366755 124366880 124371023 124372989

MQU:	129003176 129003978 129004273

PHU:	Phum_PHUM105710

FOC:

TPAL:

ZNE:

CSEC:

IEL:

DPX:	DAPPUDRAFT_231057

DMK:

116918078

DPZ:

124314470

PVM:	113802141 113823303 113823305 113823306 113823307

PJA:	122243005 122244771 122263091 122263793

PCHN:

125025320 125043302 125043336

PMOO:

119585047 119585048 119585050

HAME:

121862570 121870290 121878171 121878883

PCLA:

123767634 123767635 123767637 123767638 123768387

CQD:	128697757 128697758

PTRU:

123503391 123509526 123509528 123509529

ESN:	126986611 126986612 126986613 127006659

MNZ:	135219958 135222626 135226416

HAZT:

108678554

EAF:

111711488

LSM:	121131647 121132011

TCF:

131876925

PPOI:

119095669 119109603

ISC:

8036218

RMP:	119160888 119171557 119171558 119171720 119171721 119173631 119177352 119177832 119178227 119178228 119183138 119188165 119188166 119188167 119188169 119188171 119188204

VDE:

VJA:

TUT:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

106456866 106469791 106474081

CEL:	CELE_F09E10.3(dhs-25) CELE_Y39A1A.11(dhs-11)

CBR:	CBG_18334(Cbr-dhs-11) CBG_24510(Cbr-dhs-25)

CRQ:	GCK72_010431 GCK72_022291

NAI:	NECAME_03347

LGI:	LOTGIDRAFT_190314

PVUL:

126827818

PCAN:

112575234

BGT:

106059170

GAE:	121366790 121384358

HRF:

HRJ:

CRG:

CANU:

CVN:	111123213 111125936

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:	106152961 106172053

LLON:

NVE:

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:

XEN:	124439891 124456532

HMG:

100199027

HSY:

130622359

FCY:	FRACYDRAFT_232706

» show all

Reference

PMID:17978863

Authors

Ohno S, Nishikawa K, Honda Y, Nakajin S

Title

Expression in E. coli and tissue distribution of the human homologue of the mouse Ke 6 gene, 17beta-hydroxysteroid dehydrogenase type 8.

Journal

Mol Cell Biochem 309:209-15 (2008)
DOI:10.1007/s11010-007-9637-9

Reference

PMID:19571038

Authors

Chen Z, Kastaniotis AJ, Miinalainen IJ, Rajaram V, Wierenga RK, Hiltunen JK

Title

17beta-hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS.

Journal

FASEB J 23:3682-91 (2009)
DOI:10.1096/fj.09-133587

All links

Ontology (4)   
   KEGG BRITE (2)   
   GO (2)   
Pathway (10)   
   KEGG PATHWAY (8)   
   KEGG MODULE (2)   
Chemical reaction (11)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
   KEGG RCLASS (2)   
Gene (1728)   
   KEGG GENES (732)   
   KEGG MGENES (100)   
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ORTHOLOGY: K13368

Entry

K13368                      KO

Symbol

HSD17B2

Name

17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]

Pathway

map00140

Steroid hormone biosynthesis

map01100

Metabolic pathways

map04913

Ovarian steroidogenesis

Module

M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

Reaction

R01836

testosterone:NAD+ 17-oxidoreductase

R02352

estradiol-17beta:NAD+ 17-oxidoreductase

R02353

estradiol-17beta:NADP+ 17-oxidoreductase

R04681

estriol:NAD+ 17-oxidoreductase

R04682

estriol:NADP+ 17-oxidoreductase

R08945

11beta,17beta-dihydroxy-4-androsten-3-one:NAD+ 17-oxidoreductase

R08980

11beta,17beta-dihydroxy-4-androsten-3-one:NADP+ 17-oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)

Other DBs

GO:	0004303 0047035

Genes

HSA:	3294(HSD17B2)

PTR:	454269(HSD17B2)

PPS:	100983435(HSD17B2)

GGO:	101131453(HSD17B2)

PON:	100456547(HSD17B2)

PPYG:

129016155(HSD17B2)

NLE:	100588757(HSD17B2)

HMH:	116470773(HSD17B2)

SSYN:

129493403(HSD17B2)

MCC:	714282(HSD17B2)

MCF:	102119721(HSD17B2)

MTHB:

126943976

MNI:	105491202(HSD17B2)

CSAB:

103233373(HSD17B2)

CATY:

105598042(HSD17B2)

PANU:

101005026(HSD17B2)

TGE:	112614126(HSD17B2)

MLEU:

105546785(HSD17B2)

RRO:	104671622(HSD17B2)

RBB:	108521311(HSD17B2)

TFN:	117088115(HSD17B2)

PTEH:

111552544(HSD17B2)

CANG:

105511945(HSD17B2)

CJC:	100390710(HSD17B2)

SBQ:	101030366(HSD17B2)

CIMI:

108313464(HSD17B2)

ANAN:

105726627(HSD17B2)

CSYR:

103267385(HSD17B2)

MMUR:

105859478(HSD17B2)

LCAT:

123625046(HSD17B2)

PCOQ:

105813484(HSD17B2)

OGA:	100948519(HSD17B2)

MMU:	15486(Hsd17b2)

MCAL:

110299663(Hsd17b2)

MPAH:

110337701(Hsd17b2)

RNO:	79243(Hsd17b2)

MCOC:

116070254(Hsd17b2)

ANU:	117723193(Hsd17b2)

MUN:	110550260(Hsd17b2)

CGE:	100751897(Hsd17b2)

MAUA:

101841187(Hsd17b2)

PROB:

127234513(Hsd17b2)

PLEU:

114697459(Hsd17b2)

MORG:

121447250(Hsd17b2)

MFOT:

126502938

AAMP:

119801690(Hsd17b2)

NGI:	103748738(Hsd17b2)

HGL:	101719685(Hsd17b2)

CPOC:

100731231(Hsd17b2)

CCAN:

109680174

DORD:

105983081(Hsd17b2)

DSP:	122101103(Hsd17b2)

PLOP:

125357865(Hsd17b2)

NCAR:

124967024

MMMA:

107150866(Hsd17b2)

OCU:

100358604

TUP:	102481564(HSD17B2)

GVR:	103591524(HSD17B2)

CFA:	489690(HSD17B2)

CLUD:

112646725(HSD17B2)

VVP:	112912332(HSD17B2)

VLG:	121499310(HSD17B2)

NPO:	129497933(HSD17B2)

AML:	100484508(HSD17B2)

UMR:	103662132(HSD17B2)

UAH:	113252538(HSD17B2)

UAR:	123791352(HSD17B2)

ELK:

111152983

LLV:

125089092

MPUF:

101694208(HSD17B2)

MNP:	132005179(HSD17B2)

MLK:	131817958(HSD17B2)

NVS:	122911193(HSD17B2)

ORO:	101379076(HSD17B2)

EJU:	114203848(HSD17B2)

ZCA:	113936101(HSD17B2)

MLX:	118023526(HSD17B2)

NSU:	110591764(HSD17B2)

LWW:	102731014(HSD17B2)

FCA:	101085592(HSD17B2)

PYU:	121009854(HSD17B2)

PBG:	122494522(HSD17B2)

PVIV:

125153010(HSD17B2)

LRUF:

124510729

PTG:	102958819(HSD17B2)

PPAD:

109245636(HSD17B2)

PUC:

125916314

AJU:

106984011

HHV:	120225544(HSD17B2)

BTA:	515710(HSD17B2)

BOM:	102278674(HSD17B2)

BIU:	109572993(HSD17B2)

BBUB:

102406091(HSD17B2)

BBIS:

104996522(HSD17B2)

CHX:	102182621(HSD17B2)

OAS:	100913161(HSD17B2)

BTAX:

128063826(HSD17B2)

ODA:	120873244(HSD17B2)

CCAD:

122421656(HSD17B2)

MBEZ:

129547228(HSD17B2)

SSC:	100312973(HSD17B2)

CFR:	102514993(HSD17B2)

CBAI:

105078954(HSD17B2)

CDK:	105089442(HSD17B2)

VPC:	102541386(HSD17B2)

BACU:

103014202(HSD17B2)

BMUS:

118885591(HSD17B2)

LVE:	103070446(HSD17B2)

OOR:	101284697(HSD17B2)

DLE:	111179344(HSD17B2)

PSIU:

116744208(HSD17B2)

NASI:

112393444(HSD17B2)

ECB:	100146214(HSD17B2)

EPZ:	103558215(HSD17B2)

EAI:	106832532(HSD17B2)

MYB:	102260774(HSD17B2)

MYD:	102751454(HSD17B2)

MMYO:

118674766(HSD17B2)

MLF:	102419373(HSD17B2)

MDT:	132217202(HSD17B2)

PKL:	118720592(HSD17B2)

EFUS:

103284405(HSD17B2)

MNA:	107525681(HSD17B2)

DRO:	112300652(HSD17B2)

SHON:

118983035(HSD17B2)

AJM:	119047101(HSD17B2)

PDIC:

114488332(HSD17B2)

PHAS:

123805995(HSD17B2)

MMF:	118639044(HSD17B2)

PPAM:

129075044(HSD17B2)

HAI:	109378375(HSD17B2)

RFQ:	117034315(HSD17B2)

PALE:

102882881(HSD17B2)

PGIG:

120622969(HSD17B2)

PVP:	105289833(HSD17B2)

RAY:	107521360(HSD17B2)

MJV:	108400471(HSD17B2)

TOD:	119249123(HSD17B2)

SARA:

101553564(HSD17B2)

SETR:

126028463(HSD17B2)

LAV:	100673988(HSD17B2)

TMU:

101341742

ETF:	101643607(HSD17B2)

DNM:	101427521(HSD17B2)

MDO:	100031815(HSD17B2)

GAS:	123237041(HSD17B2)

SHR:	100921563(HSD17B2)

AFZ:

127548675

PCW:	110212686(HSD17B2)

TVP:	118844485(HSD17B2)

OAA:	100076931(HSD17B2)

GGA:	415807(HSD17B2)

PCOC:

116243844(HSD17B2)

MGP:	100549838(HSD17B2)

CJO:	107319415(HSD17B2)

TPAI:

128082058(HSD17B2)

LMUT:

125699046(HSD17B2)

NMEL:

110404501(HSD17B2)

APLA:

101792379(HSD17B2)

ACYG:

106044875(HSD17B2)

CATA:

118246468(HSD17B2)

AFUL:

116494039(HSD17B2)

TGU:	100228039(HSD17B2)

LSR:	110476239(HSD17B2)

SCAN:

103816732(HSD17B2)

PMOA:

120508045(HSD17B2)

OTC:	121334039(HSD17B2)

PRUF:

121348933(HSD17B2)

GFR:	102039377(HSD17B2)

FAB:	101810951(HSD17B2)

OMA:	130257940(HSD17B2)

PHI:	102103079(HSD17B2)

PMAJ:

107209789(HSD17B2)

CCAE:

111934744(HSD17B2)

CCW:	104691825(HSD17B2)

CBRC:

103620107(HSD17B2)

ETL:	114066564(HSD17B2)

ZAB:	102065285(HSD17B2)

ZLE:	135452754(HSD17B2)

ACHL:

103804388(HSD17B2)

SVG:	106852111(HSD17B2)

MMEA:

130577294(HSD17B2)

HRT:	120757739(HSD17B2)

SATI:

136366471(HSD17B2)

FPG:	101915382(HSD17B2)

FCH:	102048922(HSD17B2)

CCRI:

104164321(HSD17B2)

NNT:

104406080

SHAB:

115601234(HSD17B2)

ACUN:

113484357(HSD17B2)

TALA:

104357344(HSD17B2)

ACHC:

115346618(HSD17B2)

HALD:

104318019(HSD17B2)

HLE:	104839382(HSD17B2)

AGEN:

126040701

GCL:

127021144

CSTI:

104559017(HSD17B2)

LDI:	104344058(HSD17B2)

MNB:	103777206(HSD17B2)

DPUB:

104300852(HSD17B2)

AVIT:

104276875(HSD17B2)

BRHI:

104494747(HSD17B2)

EGZ:	104133743(HSD17B2)

NNI:	104014591(HSD17B2)

PCRI:

104035479(HSD17B2)

PCAO:

104052762(HSD17B2)

PADL:

103923867(HSD17B2)

AFOR:

103897306(HSD17B2)

FGA:	104080739(HSD17B2)

GSTE:

104261743(HSD17B2)

CLV:	102095570(HSD17B2)

MUI:	104536601(HSD17B2)

PGUU:

104468180(HSD17B2)

PLET:

104620781(HSD17B2)

EHS:

104508678

CMAC:

104480014

CUCA:

104059402(HSD17B2)

TEO:	104372565(HSD17B2)

BREG:

104639884(HSD17B2)

OHA:	104339199(HSD17B2)

ACAR:

104529221(HSD17B2)

CPEA:

104396360(HSD17B2)

CVF:	104291178(HSD17B2)

RTD:	128909655(HSD17B2)

AAM:	106483270(HSD17B2)

AROW:

112963132(HSD17B2)

NPD:	112949904(HSD17B2)

TGT:	104567310(HSD17B2)

DNE:	112978869(HSD17B2)

SCAM:

104149336(HSD17B2)

ASN:	102375872(HSD17B2)

AMJ:	102574309(HSD17B2)

CPOO:

109310653(HSD17B2)

GGN:	109289465(HSD17B2)

PSS:	102453984(HSD17B2)

CMY:	102941631(HSD17B2)

CCAY:

125620723(HSD17B2)

DCC:	119840996(HSD17B2)

CPIC:

101941193(HSD17B2)

TST:	117886839(HSD17B2)

CABI:

116816710(HSD17B2)

MRV:	120384420(HSD17B2)

ASAO:

132783051(HSD17B2)

PVT:	110090097(HSD17B2)

SUND:

121914651(HSD17B2)

PBI:	103058540(HSD17B2)

PMUR:

107287717(HSD17B2)

CTIG:

120312099(HSD17B2)

PGUT:

117670961(HSD17B2)

APRI:

131184233(HSD17B2)

PTEX:

113444995(HSD17B2)

NSS:	113424570(HSD17B2)

VKO:	123022312(HSD17B2)

PMUA:

114602206(HSD17B2)

PRAF:

128419440(HSD17B2)

ZVI:	118087060(HSD17B2)

HCG:	128334597(HSD17B2)

GJA:	107109831(HSD17B2)

EMC:	129343822(HSD17B2)

XLA:	108714085(hsd17b2.L)

XTR:	100497002(hsd17b2)

NPR:	108786564(HSD17B2)

RTEM:

120917949(HSD17B2)

BBUF:

120980090(HSD17B2)

MUO:	115469904(HSD17B2)

GSH:	117359166(HSD17B2)

DRE:	449537(hsd17b2)

SRX:

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

122330811(hsd17b2)

LROH:

127156571(hsd17b2)

OMC:	131534314(hsd17b2)

PPRM:

120468188(hsd17b2)

RKG:	130080378(hsd17b2)

MAMB:

125247415(hsd17b2)

CIDE:

127507010

CERY:

137014939(hsd17b2)

MASI:

127437468

TROS:

130550814(hsd17b2)

TDW:	130413901(hsd17b2)

MANU:

129434373(hsd17b2)

IPU:	108275401(hsd17b2)

IFU:	128617825(hsd17b2)

PHYP:

113529589

SMEO:

124392856(hsd17b2)

TFD:	113659887(hsd17b2)

TVC:	132857549(hsd17b2)

TRN:	134320444(hsd17b2)

AMEX:

103032973(hsd17b2)

CMAO:

118811626(hsd17b2)

EEE:

113573186

TRU:

101071919

TFS:	130535658(hsd17b2)

LCO:	104938964(hsd17b2)

CGOB:

115005645

ELY:	117262723(hsd17b2)

EFO:	125887122(hsd17b2)

SLUC:

116060807(hsd17b2)

PFLV:

114560137(hsd17b2)

AFB:	129108857(hsd17b2)

MSAM:

119894425(hsd17b2)

SCHU:

122875199(hsd17b2)

ALAT:

119023816(hsd17b2)

AOCE:

111585754

CSEM:

103379612(hsd17b2)

SSEN:

122775401(hsd17b2)

HHIP:

117762652(hsd17b2) 117763120

HSP:	118110216(hsd17b2)

PPLT:

128444019(hsd17b2)

SMAU:

118314758(hsd17b2)

LCF:	108885234(hsd17b2)

SDU:

111233733

SLAL:

111647408

BPEC:

110162637(hsd17b2)

MALB:

109969153(hsd17b2)

BSPL:

114857018(hsd17b2)

SJO:	128359046(hsd17b2)

SASA:

106561531(hsd17b2)

STRU:

115197518(hsd17b2)

OTW:	112218829(hsd17b2)

OMY:	110499264(hsd17b2)

OGO:	124033783(hsd17b2)

ONE:	115133991(hsd17b2)

OKI:	109866803(hsd17b2)

OKE:	118395927(hsd17b2)

SALP:

111962699(hsd17b2)

SNH:	120066711(hsd17b2)

CCLU:

121532165(hsd17b2)

ELS:	105018101(hsd17b2)

LOC:	102692720(hsd17b2)

PSPA:

121325469 121325854

ARUT:

117424683 117425386

PSEX:

120535558(hsd17b2)

LCM:	102360275(HSD17B2)

CMK:

103191276

RTP:	109928139(hsd17b2)

CPLA:

122558269(hsd17b2)

HOC:	132823892(hsd17b2)

LERI:

129705386(hsd17b2)

LRJ:

BFO:

BBEL:

SPU:

LPIC:

APLC:

110977970 110988430 110988439

ARUN:

117305006

SKO:	100368354 100374321

NVL:

RMP:

TUT:

DFR:

PTEP:

107436613 107442495 107442496 107450562

ABRU:

UDV:

SDM:

LPOL:

PVUL:

PCAN:

GAE:

HRF:

CRG:	105320727 105342689

CANU:

128178694 128191713

CVN:

111113370

OED:	125681672 125683552

MYI:	110444395 110447833 110457855

PMAX:

MMER:

RPHI:

DPOL:

MAEA:

OBI:	106872799 106879333 106879334

OSN:	115212282 115212360 115213937

LJP:	135467448 135475279

LAK:	106154383 106157985

LLON:

135492295

» show all

Reference

PMID:8099587

Authors

Wu L, Einstein M, Geissler WM, Chan HK, Elliston KO, Andersson S

Title

Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity.

Journal

J Biol Chem 268:12964-9 (1993)

Sequence

[hsa:3294]

Reference

PMID:19022235

Authors

Smuc T, Rizner TL

Title

Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines.

Journal

Chem Biol Interact 178:228-33 (2009)
DOI:10.1016/j.cbi.2008.10.038

Reference

PMID:19737616

Authors

Plante J, Simard M, Rantakari P, Cote M, Provost PR, Poutanen M, Tremblay Y

Title

Epithelial cells are the major site of hydroxysteroid (17beta) dehydrogenase 2 and androgen receptor expression in fetal mouse lungs during the period overlapping the surge of surfactant.

Journal

J Steroid Biochem Mol Biol 117:139-45 (2009)
DOI:10.1016/j.jsbmb.2009.08.006

All links

Ontology (4)   
   KEGG BRITE (2)   
   GO (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (11)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
   KEGG RCLASS (2)   
Gene (518)   
   KEGG GENES (407)   
   KEGG MGENES (31)   
   RefGene (76)   
   OC (4)   
Literature (3)   
   PubMed (3)   
All databases (543)   

Download RDF

ORTHOLOGY: K13369

Entry

K13369                      KO

Symbol

HSD17B6

Name

17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]

Pathway

map00140

Steroid hormone biosynthesis

map00830

Retinol metabolism

map01100

Metabolic pathways

map01240

Biosynthesis of cofactors

Module

M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

M00977

C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone

Reaction

R01836

testosterone:NAD+ 17-oxidoreductase

R02124

retinol:NAD+ oxidoreductase

R02352

estradiol-17beta:NAD+ 17-oxidoreductase

R02353

estradiol-17beta:NADP+ 17-oxidoreductase

R02476

androsterone:NAD+ oxidoreductase

R04330

androstan-3alpha,17beta-diol:NAD+ oxidoreductase

R04681

estriol:NAD+ 17-oxidoreductase

R04682

estriol:NADP+ 17-oxidoreductase

R08945

11beta,17beta-dihydroxy-4-androsten-3-one:NAD+ 17-oxidoreductase

R08980

11beta,17beta-dihydroxy-4-androsten-3-one:NADP+ 17-oxidoreductase

R13216

5alpha-pregnane-3alpha,17alpha-diol-20-one:NAD+ oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
    1.1.1.105  all-trans-retinol dehydrogenase (NAD+)
     K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)

Other DBs

GO:	0004303 0004745 0047035

Genes

HSA:	8630(HSD17B6)

PPS:	100996145(HSD17B6)

GGO:

101153072

PON:	100454653 100458219(HSD17B6)

PPYG:

129010009(HSD17B6)

NLE:

100606923

HMH:

116480891

SSYN:

129465575

MCC:	713549(HSD17B6)

MCF:	101926544(HSD17B6)

MTHB:

126930391

MNI:	105474127(HSD17B6)

CSAB:

103238543(HSD17B6)

CATY:

105587281(HSD17B6)

TGE:

112634424

MLEU:

105545551(HSD17B6)

RRO:	104673659(HSD17B6)

RBB:	108516069(HSD17B6)

TFN:	117089914(HSD17B6)

PTEH:

111541833(HSD17B6)

CANG:

105500532(HSD17B6)

CJC:	100387390(HSD17B6)

SBQ:	101054253(HSD17B6)

CIMI:

108309703(HSD17B6)

ANAN:

105715970(HSD17B6)

CSYR:

103275150(HSD17B6) 103275152

MMUR:

105865568

LCAT:

123639631 123639632(HSD17B6)

PCOQ:

105816028

OGA:

100947460

MMU:	27400(Hsd17b6)

MCAL:

110303948

MPAH:

110326955(Hsd17b6)

RNO:	134479803 286964(Hsd17b6)

MCOC:

116076149

ANU:

117696662

CGE:

100762147

PROB:

127215652(Hsd17b6)

PLEU:

MORG:

MFOT:

AAMP:

NGI:	103730224(Hsd17b6)

HGL:	101699287(Hsd17b6)

CPOC:

100717492 100717768 100718054

CCAN:

109686095

DORD:

105986857(Hsd17b6)

DSP:	122124416(Hsd17b6)

PLOP:

125362512(Hsd17b6)

TUP:	102485005(HSD17B6)

CFA:	481118(HSD17B6)

CLUD:

112678001(HSD17B6)

VVP:	112922366(HSD17B6)

VLG:	121491966(HSD17B6)

NPO:

129511964

AML:

100474694

UMR:	103656323(HSD17B6)

UAH:	113256406(HSD17B6)

UAR:	123787236(HSD17B6)

ELK:

111160200

LLV:

125106172

MPUF:

101672306(HSD17B6)

MNP:	132019817(HSD17B6)

MLK:	131838584(HSD17B6)

NVS:	122892252(HSD17B6)

ORO:	101368715(HSD17B6)

EJU:	114215053(HSD17B6)

ZCA:	113921488(HSD17B6)

MLX:

118008692

NSU:

110577830

LWW:	102743313(HSD17B6)

FCA:	101088341(HSD17B6)

PYU:	121040906(HSD17B6)

PCOO:

112863243(HSD17B6)

PBG:	122473787(HSD17B6)

PVIV:

125170822(HSD17B6)

LRUF:

124502205

PTG:	102971783(HSD17B6)

PPAD:

109270351(HSD17B6)

PUC:

125920256

AJU:

106986922

HHV:	120224864(HSD17B6)

BTA:	533086(HSD17B6)

BOM:	102283510(HSD17B6)

BIU:

BBUB:

BBIS:

CHX:

OAS:

BTAX:

ODA:

CCAD:

MBEZ:

SSC:

CFR:

CBAI:

CDK:

VPC:	102527912 102534817 107034922

BACU:

103008169(HSD17B6)

BMUS:

118902700

LVE:	103076064(HSD17B6)

OOR:	101278484(HSD17B6)

DLE:	111173857(HSD17B6)

PCAD:

102988625

PSIU:

116761374

NASI:

112393956(HSD17B6)

ECB:

100052840

EPZ:	103565330(HSD17B6)

EAI:	106832977(HSD17B6)

MMF:

118623751

RFQ:

117028833

PALE:

102883634(HSD17B6)

PGIG:

120604931

PVP:

105302561

RAY:	107521200(HSD17B6)

MJV:

LAV:

TMU:

SHR:

AFZ:

PCW:

TVP:	118850303 118850652 118850653 118851548 118851597

AROW:

112962016

NPD:

112956391

DNE:

112994731

ASN:	102370921 102371169

AMJ:

102567845

CPOO:

109324411 109324469

PSS:	102444001 102454079

CMY:

102944543

CCAY:

125627856

DCC:	119845913(HSD17B6)

CPIC:

103306704

TST:	117888588(HSD17B6)

CABI:

116827724

MRV:

120391156

ACS:	100564174(hsd17b6)

ASAO:

132768358 132768360

PVT:	110071325 110091362

SUND:

PBI:

PMUR:

CTIG:

TSR:	106545328(HSD17B6)

PGUT:

117662721

APRI:

131192991 131193302(HSD17B6)

PTEX:

113445491 113445552

NSS:	113422732 113422749

PMUA:

114592701 114592979 114592981

PRAF:

128405337 128405345 128405364 128405369 128405390

ZVI:	118077226(HSD17B6)

HCG:	128339160 128339162 128344041 128345225 128345226 128346238 128346556 128346634

GJA:	107120904(HSD17B6)

STOW:

125430225 125430298 125430340

EMC:	129328144 129346101 129346224

XTR:

GSH:

BROR:

DSV:

RMP:

LOA:	LOAG_08821

LGI:	LOTGIDRAFT_141736

PCAN:

112563790 112563794 112563795

BGT:

HRJ:

CRG:

CANU:

CVN:	111111885 111114621

MYI:	110451842 110466177

PMAX:

117316732 117316733 117316734 117318303

MCAF:

127719989

MMER:

123531644 123531645 123532231

RPHI:

132715842 132719757 132734128 132736821 132737641 132737771 132738844

DPOL:

127855977

MAEA:

128208576 128236155 128236793 128237301 128244468 128244563

OBI:

106873408

HSY:

130655463

TAD:	TRIADDRAFT_22801

» show all

Reference

PMID:9188497

Authors

Biswas MG, Russell DW

Title

Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate.

Journal

J Biol Chem 272:15959-66 (1997)
DOI:10.1074/jbc.272.25.15959

Sequence

[hsa:8630] [rno:286964]

Reference

PMID:11360992

Authors

Chetyrkin SV, Hu J, Gough WH, Dumaual N, Kedishvili NY

Title

Further characterization of human microsomal 3alpha-hydroxysteroid dehydrogenase.

Journal

Arch Biochem Biophys 386:1-10 (2001)
DOI:10.1006/abbi.2000.2203

Sequence

[hsa:8630]

All links

Ontology (5)   
   KEGG BRITE (2)   
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Pathway (10)   
   KEGG PATHWAY (8)   
   KEGG MODULE (2)   
Chemical reaction (18)   
   KEGG ENZYME (3)   
   KEGG REACTION (11)   
   KEGG RCLASS (4)   
Gene (257)   
   KEGG GENES (235)   
   KEGG MGENES (1)   
   RefGene (19)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (292)   

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