KEGG   ORTHOLOGY: K13377
Entry
K13377                      KO                                     
Symbol
TGFB3
Name
transforming growth factor beta-3
Pathway
map04010  MAPK signaling pathway
map04060  Cytokine-cytokine receptor interaction
map04068  FoxO signaling pathway
map04110  Cell cycle
map04218  Cellular senescence
map04350  TGF-beta signaling pathway
map04390  Hippo signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map05140  Leishmaniasis
map05142  Chagas disease
map05144  Malaria
map05145  Toxoplasmosis
map05146  Amoebiasis
map05152  Tuberculosis
map05161  Hepatitis B
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05220  Chronic myeloid leukemia
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05321  Inflammatory bowel disease
map05323  Rheumatoid arthritis
map05410  Hypertrophic cardiomyopathy
map05414  Dilated cardiomyopathy
map05415  Diabetic cardiomyopathy
Disease
H00083  Allograft rejection
H00084  Graft-versus-host disease
H00293  Arrhythmogenic right ventricular cardiomyopathy
H00431  Ossification of the posterior longitudinal ligament of spine
H00800  Loeys-Dietz syndrome
H01385  Rienhoff syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
   04350 TGF-beta signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
   04390 Hippo signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
   04068 FoxO signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13377  TGFB3; transforming growth factor beta-3
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K13377  TGFB3; transforming growth factor beta-3
   04218 Cellular senescence
    K13377  TGFB3; transforming growth factor beta-3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K13377  TGFB3; transforming growth factor beta-3
  09162 Cancer: specific types
   05210 Colorectal cancer
    K13377  TGFB3; transforming growth factor beta-3
   05212 Pancreatic cancer
    K13377  TGFB3; transforming growth factor beta-3
   05225 Hepatocellular carcinoma
    K13377  TGFB3; transforming growth factor beta-3
   05226 Gastric cancer
    K13377  TGFB3; transforming growth factor beta-3
   05220 Chronic myeloid leukemia
    K13377  TGFB3; transforming growth factor beta-3
   05211 Renal cell carcinoma
    K13377  TGFB3; transforming growth factor beta-3
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K13377  TGFB3; transforming growth factor beta-3
   05161 Hepatitis B
    K13377  TGFB3; transforming growth factor beta-3
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K13377  TGFB3; transforming growth factor beta-3
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K13377  TGFB3; transforming growth factor beta-3
   05144 Malaria
    K13377  TGFB3; transforming growth factor beta-3
   05145 Toxoplasmosis
    K13377  TGFB3; transforming growth factor beta-3
   05140 Leishmaniasis
    K13377  TGFB3; transforming growth factor beta-3
   05142 Chagas disease
    K13377  TGFB3; transforming growth factor beta-3
  09163 Immune disease
   05323 Rheumatoid arthritis
    K13377  TGFB3; transforming growth factor beta-3
   05321 Inflammatory bowel disease
    K13377  TGFB3; transforming growth factor beta-3
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K13377  TGFB3; transforming growth factor beta-3
   05414 Dilated cardiomyopathy
    K13377  TGFB3; transforming growth factor beta-3
   05415 Diabetic cardiomyopathy
    K13377  TGFB3; transforming growth factor beta-3
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K13377  TGFB3; transforming growth factor beta-3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K13377  TGFB3; transforming growth factor beta-3
Cytokines and neuropeptides [BR:ko04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   K13377  TGFB3; transforming growth factor beta-3
Genes
HSA: 7043(TGFB3)
PTR: 453054(TGFB3)
PPS: 100990987(TGFB3)
GGO: 101133741(TGFB3)
PON: 100433208(TGFB3)
PPYG: 129012456(TGFB3)
NLE: 100591391(TGFB3)
HMH: 116456166(TGFB3)
SSYN: 129487631(TGFB3)
MCC: 703239(TGFB3)
MCF: 102119907(TGFB3)
MTHB: 126959539
MNI: 105495762(TGFB3)
CSAB: 103229367(TGFB3)
CATY: 105590879(TGFB3)
PANU: 100997116(TGFB3)
TGE: 112629301(TGFB3)
MLEU: 105540815(TGFB3)
RRO: 104677599(TGFB3)
RBB: 108534939(TGFB3)
TFN: 117069299(TGFB3)
PTEH: 111555026(TGFB3)
CANG: 105517128(TGFB3)
CJC: 100392463(TGFB3)
SBQ: 101048819(TGFB3)
CIMI: 108304431(TGFB3)
ANAN: 105707223(TGFB3)
CSYR: 103260508(TGFB3)
MMUR: 105858956(TGFB3)
LCAT: 123646462(TGFB3)
PCOQ: 105819930(TGFB3)
OGA: 100955213(TGFB3)
MMU: 21809(Tgfb3)
MCAL: 110306834(Tgfb3)
MPAH: 110324521(Tgfb3)
RNO: 25717(Tgfb3)
MCOC: 116080097(Tgfb3)
ANU: 117697375(Tgfb3)
MUN: 110558214(Tgfb3)
CGE: 100756831(Tgfb3)
MAUA: 101840590(Tgfb3)
PROB: 127230997(Tgfb3)
PLEU: 114697904(Tgfb3)
MORG: 121452547(Tgfb3)
MFOT: 126507732
AAMP: 119819138(Tgfb3)
NGI: 103739777(Tgfb3)
HGL: 101712904(Tgfb3)
CPOC: 100715426(Tgfb3)
CCAN: 109686152(Tgfb3)
DORD: 105983993(Tgfb3)
DSP: 122118877(Tgfb3)
PLOP: 125363309(Tgfb3)
NCAR: 124977343
MMMA: 107149439(Tgfb3)
OCU: 100358982
OPI: 101525102(TGFB3)
TUP: 102497029(TGFB3)
GVR: 103585960(TGFB3)
CFA: 490796(TGFB3)
CLUD: 112657820(TGFB3)
VVP: 112927298(TGFB3)
VLG: 121493196(TGFB3)
NPO: 129496088(TGFB3)
AML: 100475861(TGFB3)
UMR: 103670922(TGFB3)
UAH: 113270312(TGFB3)
UAR: 123798962(TGFB3)
ELK: 111148592
LLV: 125103650
MPUF: 101678400(TGFB3)
MNP: 132000151(TGFB3)
MLK: 131836852(TGFB3)
NVS: 122893231(TGFB3)
ORO: 101364584(TGFB3)
EJU: 114207516(TGFB3)
ZCA: 113910186(TGFB3)
MLX: 118002625(TGFB3)
NSU: 110571461(TGFB3)
LWW: 102738835(TGFB3)
FCA: 101098469(TGFB3)
PYU: 121032078(TGFB3)
PCOO: 112855350(TGFB3)
PBG: 122469354(TGFB3)
PVIV: 125168683(TGFB3)
LRUF: 124512625
PTG: 102949760(TGFB3)
PPAD: 109253865(TGFB3)
PUC: 125908676
AJU: 106974351
HHV: 120231992(TGFB3)
BTA: 538957(TGFB3)
BOM: 102265567(TGFB3)
BIU: 109565371(TGFB3)
BBUB: 102389416(TGFB3)
BBIS: 104991770(TGFB3)
CHX: 102189962(TGFB3)
OAS: 554323(TGFB3)
BTAX: 128053888(TGFB3)
ODA: 120852691(TGFB3)
CCAD: 122443885(TGFB3)
MBEZ: 129562431(TGFB3)
SSC: 397400(TGFB3)
CFR: 102517948(TGFB3)
CBAI: 105075375(TGFB3)
CDK: 105086078(TGFB3)
VPC: 102534848(TGFB3)
BACU: 103001029(TGFB3)
BMUS: 118891006(TGFB3)
LVE: 103086562(TGFB3)
OOR: 101289027(TGFB3)
DLE: 111176232(TGFB3)
PCAD: 102977345(TGFB3)
PSIU: 116749145(TGFB3)
NASI: 112394874(TGFB3)
ECB: 100051765(TGFB3)
EPZ: 103555506(TGFB3)
EAI: 106830938(TGFB3)
MYB: 102249502(TGFB3)
MYD: 102767291(TGFB3)
MMYO: 118658350(TGFB3)
MLF: 102441450(TGFB3)
MDT: 132231120(TGFB3)
PKL: 118715108 118715117
EFUS: 103283554(TGFB3)
MNA: 107533843(TGFB3)
DRO: 112311221(TGFB3)
SHON: 118976756(TGFB3)
AJM: 119049266(TGFB3)
PDIC: 114492736(TGFB3)
PHAS: 123808879(TGFB3)
MMF: 118633354(TGFB3)
PPAM: 129065729(TGFB3)
HAI: 109381619(TGFB3)
RFQ: 117023034(TGFB3)
PALE: 102893304(TGFB3)
PGIG: 120619522(TGFB3)
PVP: 105299206(TGFB3)
RAY: 107498899(TGFB3)
MJV: 108404608(TGFB3)
TOD: 119239348(TGFB3)
SARA: 101546290(TGFB3)
SETR: 126004037(TGFB3)
LAV: 100653832(TGFB3)
TMU: 101358028
ETF: 101642513(TGFB3)
DNM: 101434549(TGFB3)
MDO: 100017937(TGFB3)
GAS: 123235863(TGFB3)
SHR: 100929617(TGFB3)
AFZ: 127549479
PCW: 110208305(TGFB3)
TVP: 118828064(TGFB3)
OAA: 100074840(TGFB3)
GGA: 396438(TGFB3)
PCOC: 116228975(TGFB3)
MGP: 100544554(TGFB3) 109364721
CJO: 107315120(TGFB3)
TPAI: 128086966(TGFB3)
LMUT: 125695556(TGFB3)
NMEL: 110401408(TGFB3)
APLA: 101802287(TGFB3)
ACYG: 106038869(TGFB3)
CATA: 118244426(TGFB3)
AFUL: 116490182(TGFB3)
TGU: 100232487(TGFB3)
LSR: 110477235(TGFB3)
SCAN: 103826906 115485432
PMOA: 120500429(TGFB3)
OTC: 121332674(TGFB3)
PRUF: 121355988(TGFB3)
GFR: 102037028(TGFB3)
FAB: 101809258(TGFB3)
OMA: 130253399(TGFB3)
PHI: 102102248(TGFB3)
PMAJ: 107205526(TGFB3)
CCAE: 111929961(TGFB3)
CCW: 104685280(TGFB3)
CBRC: 103620878(TGFB3)
ETL: 114056022(TGFB3)
ZAB: 102066760(TGFB3)
ZLE: 135448616(TGFB3)
ACHL: 103807798(TGFB3)
SVG: 106861616(TGFB3)
MMEA: 130579221(TGFB3)
HRT: 120753598(TGFB3)
SATI: 136362993(TGFB3)
FPG: 101912650(TGFB3)
FCH: 102055453(TGFB3)
CCRI: 104166693(TGFB3)
NNT: 104411056(TGFB3)
SHAB: 115606480(TGFB3)
ACUN: 113480465(TGFB3)
TALA: 104366482(TGFB3)
ACHC: 115336342(TGFB3)
HALD: 104321540(TGFB3)
HLE: 104841819(TGFB3)
AGEN: 126049246
GCL: 127017011
CSTI: 104562556(TGFB3)
LDI: 104344552(TGFB3)
MNB: 103779101(TGFB3)
DPUB: 104308192(TGFB3)
AVIT: 104277249(TGFB3)
BRHI: 104493914(TGFB3)
EGZ: 104133279(TGFB3)
NNI: 104020998(TGFB3)
PCRI: 104033698(TGFB3)
PCAO: 104046269(TGFB3)
PADL: 103912969(TGFB3)
AFOR: 103900124(TGFB3)
FGA: 104084011(TGFB3)
GSTE: 104251892(TGFB3)
CLV: 102088125(TGFB3)
MUI: 104534643(TGFB3)
PGUU: 104466902(TGFB3)
PLET: 104617813(TGFB3)
EHS: 104504203(TGFB3)
CMAC: 104482520(TGFB3)
CUCA: 104055683(TGFB3)
TEO: 104379700(TGFB3)
BREG: 104630514(TGFB3)
OHA: 104334192(TGFB3)
ACAR: 104523981(TGFB3)
CPEA: 104385439(TGFB3)
CVF: 104288206(TGFB3)
RTD: 128908670(TGFB3)
AAM: 106482877(TGFB3)
AROW: 112961699(TGFB3)
NPD: 112958062(TGFB3)
TGT: 104572864(TGFB3)
DNE: 112995442(TGFB3)
SCAM: 104144580(TGFB3)
ASN: 102384560(TGFB3)
AMJ: 102563668(TGFB3)
CPOO: 109320856(TGFB3)
GGN: 109299319(TGFB3)
PSS: 102456369(TGFB3)
CMY: 102929710(TGFB3)
CCAY: 125639078(TGFB3)
DCC: 119857859(TGFB3)
CPIC: 101941121(TGFB3)
TST: 117876373(TGFB3)
CABI: 116837512(TGFB3)
MRV: 120405439(TGFB3)
ACS: 100551709(tgfb3)
ASAO: 132764247(TGFB3)
PVT: 110079121(TGFB3)
SUND: 121919394(TGFB3)
PBI: 103061116(TGFB3)
PMUR: 107285957(TGFB3)
CTIG: 120311758(TGFB3)
TSR: 106545079(TGFB3)
PGUT: 117665844(TGFB3)
APRI: 131187782(TGFB3)
PTEX: 113443688(TGFB3)
NSS: 113410027(TGFB3)
VKO: 123026416(TGFB3)
PMUA: 114591728(TGFB3)
PRAF: 128408860(TGFB3)
ZVI: 118081749(TGFB3)
HCG: 128330226(TGFB3)
GJA: 107116455(TGFB3)
STOW: 125427202(TGFB3)
EMC: 129324684(TGFB3)
DRE: 369195(tgfb3)
SRX: 107723269 107724242(tgfb3)
SANH: 107688075 107702240(tgfb3)
SGH: 107554783(tgfb3)
CCAR: 109060270 109107375
CAUA: 113060431 113116939
CGIB: 127975812 128031399
PTET: 122361797(tgfb3)
LROH: 127179824(tgfb3)
OMC: 131523556(tgfb3)
PPRM: 120462419(tgfb3)
RKG: 130077528(tgfb3)
MAMB: 125268277(tgfb3)
CIDE: 127498052
CERY: 137007180(tgfb3)
MASI: 127410968 127455384
TROS: 130560082(tgfb3)
TDW: 130436493(tgfb3)
MANU: 129418199(tgfb3)
IPU: 108270130
IFU: 128613220(tgfb3)
PHYP: 113538920(tgfb3)
SMEO: 124389549(tgfb3)
TFD: 113659809(tgfb3)
TVC: 132852264(tgfb3)
TRN: 134324984(tgfb3)
AMEX: 103032923(tgfb3)
CMAO: 118823493(tgfb3)
EEE: 113585931(tgfb3)
CHAR: 105909434(tgfb3) 122132153
TRU: 101065117(tgfb3) 101077955
TFS: 130516383 130540364(tgfb3)
TNG: GSTEN00030322G001 GSTEN00032323G001
LCO: 104921351(tgfb3) 104922426
NCC: 104943712(tgfb3) 104964434
TBEN: 117471526(tgfb3) 117493459
CGOB: 115003471 115027215(tgfb3)
PGEO: 117439465 117467554(tgfb3)
GACU: 117533777 117549945(tgfb3)
EMAC: 134876823 134881678(tgfb3)
ELY: 117267019(tgfb3) 117270870
EFO: 125896682 125901481(tgfb3)
PLEP: 121953311(tgfb3) 121955433
SLUC: 116035577(tgfb3) 116066112
ECRA: 117935617(tgfb3) 117961404
ESP: 116670053(tgfb3) 116706222
PFLV: 114546436(tgfb3) 114573007
GAT: 120807995 120832683(tgfb3)
PPUG: 119195082 119227800(tgfb3)
AFB: 129103200(tgfb3) 129106805
CLUM: 117727370 117751643(tgfb3)
PSWI: 130201274(tgfb3) 130202874
MSAM: 119909133 119910740(tgfb3)
SCHU: 122861438(tgfb3) 122863261
CUD: 121521710 121526006(tgfb3)
ALAT: 119004341(tgfb3) 119012715
MZE: 101467951 101470853
ONL: 100710008 100712568(tgfb3)
OAU: 116313325(tgfb3) 116314093
OLA: 101155815 101165927(tgfb3)
OML: 112157680 112162206(tgfb3)
CSAI: 133461883(tgfb3) 133464397
XMA: 102221990(tgfb3) 102223288
XCO: 114134077(tgfb3) 114158174
XHE: 116708847(tgfb3) 116734514
PRET: 103457593 103459051(tgfb3)
PFOR: 103136163(tgfb3) 103138621
PLAI: 106949081 106949827(tgfb3)
PMEI: 106919679 106923532(tgfb3)
GAF: 122825468 122845873(tgfb3)
PPRL: 129351229 129365196(tgfb3)
CVG: 107083120 107092398(tgfb3)
CTUL: 119785110 119787547(tgfb3)
GMU: 124855346(tgfb3) 124882556
NFU: 107377518 107392404(tgfb3)
KMR: 108235253(tgfb3) 108242427
ALIM: 106520481(tgfb3) 106525282
NWH: 119418181 119427883(tgfb3)
AOCE: 111568923 111572013 111578302(tgfb3)
MCEP: 124999390 125023326
CSEM: 103376789 103380810
POV: 109628154(tgfb3) 109636158
SSEN: 122759683 122782592(tgfb3)
HHIP: 117756644(tgfb3) 117758516
HSP: 118099356 118116105(tgfb3)
PPLT: 128450687(tgfb3) 128459779
SMAU: 118286691(tgfb3) 118289917
LCF: 108892510 108895683
SDU: 111225435(tgfb3) 111238468
SLAL: 111653047 111663127(tgfb3)
XGL: 120789452 120795080(tgfb3)
HCQ: 109507757(tgfb3)
SSCV: 125981395 125990317
SBIA: 133513105(tgfb3)
PEE: 133413080(tgfb3) 133417328
PTAO: 133468619 133487708(tgfb3)
BPEC: 110153435 110155280(tgfb3)
MALB: 109955077(tgfb3) 109969998
BSPL: 114847976(tgfb3) 114849930
SJO: 128375232(tgfb3)
SASA: 106571074 106590795 106608297 106611047(tgfb3)
STRU: 115151907 115162330 115172613 115175155
OTW: 112217963 112233166 112238812 112256698
OMY: 110497921(tgfb3) 110505545 110522636 110529294
OGO: 123991530 123995452 124002151(tgfb3) 124046457
ONE: 115122909 115138506 115146230
OKI: 109879529 109883380 109894503 109904055
OKE: 118362491(tgfb3) 118368308 118397920
SALP: 111963269 111968734 112075180 112078945
SNH: 120019489 120023224 120040181 120060301
CCLU: 121539280 121544909 121552669 121556169
ELS: 105015709(tgfb3) 105029941
SFM: 108930719(tgfb3) 108936661
PKI: 111844437 111852442(tgfb3)
AANG: 118226123(tgfb3) 118228983
LOC: 102691880(tgfb3)
PSPA: 121324804 121329880(tgfb3)
ARUT: 117422235 117963928
PSEX: 120518451(tgfb3)
LCM: 102358543(TGFB3)
CPLA: 122542842 122555463(tgfb3)
HOC: 132818019(tgfb3) 132836792
LERI: 129700089(tgfb3) 129714196
PMRN: 116948474
LRJ: 133352680
BFO: 118430343
APLC: 110979251
ARUN: 117296561
DSV: 119433276
ATEN: 116300211
 » show all
Reference
PMID:3164476
  Authors
ten Dijke P, Hansen P, Iwata KK, Pieler C, Foulkes JG
  Title
Identification of another member of the transforming growth factor type beta gene family.
  Journal
Proc Natl Acad Sci U S A 85:4715-9 (1988)
DOI:10.1073/pnas.85.13.4715
  Sequence
[hsa:7043]
Reference
PMID:12221089
  Authors
Bocharov EV, Korzhnev DM, Blommers MJ, Arvinte T, Orekhov VY, Billeter M, Arseniev AS
  Title
Dynamics-modulated biological activity of transforming growth factor beta3.
  Journal
J Biol Chem 277:46273-9 (2002)
DOI:10.1074/jbc.M206274200
  Sequence
[hsa:7043]
Reference
PMID:3208746
  Authors
Derynck R, Lindquist PB, Lee A, Wen D, Tamm J, Graycar JL, Rhee L, Mason AJ, Miller DA, Coffey RJ, et al.
  Title
A new type of transforming growth factor-beta, TGF-beta 3.
  Journal
EMBO J 7:3737-43 (1988)
DOI:10.1002/j.1460-2075.1988.tb03257.x
  Sequence
[hsa:7043]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (56)   
   KEGG PATHWAY (56)   
Disease (6)   
   KEGG DISEASE (6)   
Drug (1)   
   KEGG DRUG (1)   
Gene (781)   
   KEGG GENES (513)   
   KEGG MGENES (121)   
   RefGene (145)   
   OC (2)   
Literature (3)   
   PubMed (3)   
All databases (849)   

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KEGG   ORTHOLOGY: K13376
Entry
K13376                      KO                                     
Symbol
TGFB2
Name
transforming growth factor beta-2
Pathway
map04010  MAPK signaling pathway
map04060  Cytokine-cytokine receptor interaction
map04068  FoxO signaling pathway
map04110  Cell cycle
map04218  Cellular senescence
map04350  TGF-beta signaling pathway
map04380  Osteoclast differentiation
map04390  Hippo signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map05140  Leishmaniasis
map05142  Chagas disease
map05144  Malaria
map05145  Toxoplasmosis
map05146  Amoebiasis
map05152  Tuberculosis
map05161  Hepatitis B
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05220  Chronic myeloid leukemia
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05321  Inflammatory bowel disease
map05323  Rheumatoid arthritis
map05410  Hypertrophic cardiomyopathy
map05414  Dilated cardiomyopathy
map05415  Diabetic cardiomyopathy
Disease
H00083  Allograft rejection
H00084  Graft-versus-host disease
H00800  Loeys-Dietz syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
   04350 TGF-beta signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
   04390 Hippo signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
   04068 FoxO signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13376  TGFB2; transforming growth factor beta-2
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K13376  TGFB2; transforming growth factor beta-2
   04218 Cellular senescence
    K13376  TGFB2; transforming growth factor beta-2
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K13376  TGFB2; transforming growth factor beta-2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K13376  TGFB2; transforming growth factor beta-2
   05206 MicroRNAs in cancer
    K13376  TGFB2; transforming growth factor beta-2
   05205 Proteoglycans in cancer
    K13376  TGFB2; transforming growth factor beta-2
  09162 Cancer: specific types
   05210 Colorectal cancer
    K13376  TGFB2; transforming growth factor beta-2
   05212 Pancreatic cancer
    K13376  TGFB2; transforming growth factor beta-2
   05225 Hepatocellular carcinoma
    K13376  TGFB2; transforming growth factor beta-2
   05226 Gastric cancer
    K13376  TGFB2; transforming growth factor beta-2
   05220 Chronic myeloid leukemia
    K13376  TGFB2; transforming growth factor beta-2
   05211 Renal cell carcinoma
    K13376  TGFB2; transforming growth factor beta-2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K13376  TGFB2; transforming growth factor beta-2
   05161 Hepatitis B
    K13376  TGFB2; transforming growth factor beta-2
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K13376  TGFB2; transforming growth factor beta-2
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K13376  TGFB2; transforming growth factor beta-2
   05144 Malaria
    K13376  TGFB2; transforming growth factor beta-2
   05145 Toxoplasmosis
    K13376  TGFB2; transforming growth factor beta-2
   05140 Leishmaniasis
    K13376  TGFB2; transforming growth factor beta-2
   05142 Chagas disease
    K13376  TGFB2; transforming growth factor beta-2
  09163 Immune disease
   05323 Rheumatoid arthritis
    K13376  TGFB2; transforming growth factor beta-2
   05321 Inflammatory bowel disease
    K13376  TGFB2; transforming growth factor beta-2
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K13376  TGFB2; transforming growth factor beta-2
   05414 Dilated cardiomyopathy
    K13376  TGFB2; transforming growth factor beta-2
   05415 Diabetic cardiomyopathy
    K13376  TGFB2; transforming growth factor beta-2
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K13376  TGFB2; transforming growth factor beta-2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K13376  TGFB2; transforming growth factor beta-2
   00536 Glycosaminoglycan binding proteins
    K13376  TGFB2; transforming growth factor beta-2
Cytokines and neuropeptides [BR:ko04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   K13376  TGFB2; transforming growth factor beta-2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   K13376  TGFB2; transforming growth factor beta-2
Genes
HSA: 7042(TGFB2)
PTR: 457742(TGFB2)
PPS: 100985755(TGFB2)
GGO: 101125504(TGFB2)
PON: 100461291(TGFB2)
PPYG: 129007599(TGFB2)
NLE: 100596183(TGFB2)
HMH: 116457529(TGFB2)
SSYN: 129458165(TGFB2)
MCC: 707540(TGFB2)
MCF: 101925182(TGFB2)
MTHB: 126948495
MNI: 105493507(TGFB2)
CSAB: 103230082(TGFB2)
CATY: 105577004(TGFB2)
PANU: 101009253(TGFB2)
TGE: 112636300(TGFB2)
MLEU: 105544786(TGFB2)
RRO: 104662252(TGFB2)
RBB: 108528282(TGFB2)
TFN: 117074794(TGFB2)
PTEH: 111537117(TGFB2)
CANG: 105502787(TGFB2)
CJC: 100390586(TGFB2)
SBQ: 101044624(TGFB2)
CIMI: 108302657(TGFB2)
ANAN: 105722270(TGFB2)
CSYR: 103254860(TGFB2)
MMUR: 105868760(TGFB2)
LCAT: 123626839(TGFB2)
PCOQ: 105826908(TGFB2)
OGA: 100956747(TGFB2)
MMU: 21808(Tgfb2)
MCAL: 110292955(Tgfb2)
MPAH: 110321649(Tgfb2)
RNO: 81809(Tgfb2)
MCOC: 116068447(Tgfb2)
ANU: 117716112(Tgfb2)
MUN: 110549244(Tgfb2)
CGE: 100774918(Tgfb2)
MAUA: 101832748(Tgfb2)
PROB: 127223750(Tgfb2)
PLEU: 114698210(Tgfb2)
MORG: 121435842(Tgfb2)
MFOT: 126505361
AAMP: 119827432(Tgfb2)
NGI: 103728817(Tgfb2)
HGL: 101707457(Tgfb2)
CPOC: 100720726(Tgfb2)
CCAN: 109698650(Tgfb2)
DORD: 105984796(Tgfb2)
DSP: 122109464(Tgfb2)
PLOP: 125359114(Tgfb2)
NCAR: 124962328
MMMA: 107140543(Tgfb2)
OCU: 100009371(TGFB2)
OPI: 101516556(TGFB2)
TUP: 102500482(TGFB2)
GVR: 103604625(TGFB2)
CFA: 488596(TGFB2)
CLUD: 112643136(TGFB2)
VVP: 112914338(TGFB2)
VLG: 121471376(TGFB2)
NPO: 129515208(TGFB2)
AML: 100463584(TGFB2)
UMR: 103658194(TGFB2)
UAH: 113268733(TGFB2)
UAR: 123800112(TGFB2)
ELK: 111151068
LLV: 125085760
MPUF: 101677182(TGFB2)
MNP: 132025704(TGFB2)
MLK: 131815106(TGFB2)
NVS: 122918428(TGFB2)
ORO: 101380860(TGFB2)
EJU: 114210508(TGFB2)
ZCA: 113932123(TGFB2)
MLX: 118014087(TGFB2)
NSU: 110588122(TGFB2)
LWW: 102727105(TGFB2)
FCA: 101093414(TGFB2)
PYU: 121020862(TGFB2)
PCOO: 112864785(TGFB2)
PBG: 122476025(TGFB2)
PVIV: 125155525(TGFB2)
LRUF: 124510378
PTG: 102951894(TGFB2)
PPAD: 109276581(TGFB2)
PUC: 125925521
AJU: 106979500
HHV: 120221741(TGFB2)
BTA: 534069(TGFB2)
BOM: 102283491(TGFB2)
BIU: 109570509(TGFB2)
BBUB: 102390629(TGFB2)
BBIS: 104998204(TGFB2)
CHX: 100861228(TGFB2)
OAS: 554322(TGFB2)
BTAX: 128061503(TGFB2)
ODA: 120880130(TGFB2)
CCAD: 122452400(TGFB2)
MBEZ: 129551685(TGFB2)
SSC: 397084(TGFB2)
CFR: 102505811(TGFB2)
CBAI: 105083972(TGFB2)
CDK: 105100091(TGFB2)
VPC: 102543548(TGFB2)
BACU: 103001453(TGFB2)
BMUS: 118906756(TGFB2)
LVE: 103070826(TGFB2)
OOR: 101276254(TGFB2)
DLE: 111177477(TGFB2)
PCAD: 102993033(TGFB2)
PSIU: 116747679(TGFB2)
NASI: 112395811(TGFB2)
ECB: 100050377(TGFB2) 111771316
EPZ: 103543045(TGFB2)
EAI: 106836714(TGFB2)
MYB: 102250887(TGFB2)
MYD: 102755920(TGFB2)
MMYO: 118678846(TGFB2)
MLF: 102431488(TGFB2)
MDT: 132222581(TGFB2)
PKL: 118727653(TGFB2)
EFUS: 103293466(TGFB2)
MNA: 107543622(TGFB2)
DRO: 112318906(TGFB2)
SHON: 119003169(TGFB2)
AJM: 119045813(TGFB2)
PDIC: 114512425(TGFB2)
PHAS: 123804941(TGFB2)
MMF: 118640680(TGFB2)
PPAM: 129072973(TGFB2)
HAI: 109381205(TGFB2)
RFQ: 117018527(TGFB2)
PALE: 102881295(TGFB2)
PGIG: 120619172(TGFB2)
PVP: 105296163(TGFB2)
RAY: 107520844(TGFB2)
MJV: 108403151(TGFB2)
TOD: 119234883(TGFB2)
SARA: 101549205(TGFB2)
SETR: 126003348(TGFB2)
LAV: 100656534(TGFB2)
TMU: 101347669
ETF: 101639819(TGFB2)
DNM: 101444912(TGFB2)
MDO: 100017548(TGFB2)
GAS: 123247856(TGFB2)
SHR: 100914910(TGFB2)
AFZ: 127562518
PCW: 110205565(TGFB2)
TVP: 118847514(TGFB2)
OAA: 100080176(TGFB2)
GGA: 421352(TGFB2)
PCOC: 116230622(TGFB2)
MGP: 100549559(TGFB2)
CJO: 107311051(TGFB2)
TPAI: 128081780(TGFB2)
LMUT: 125689607(TGFB2)
NMEL: 110395798(TGFB2)
APLA: 101794148(TGFB2)
ACYG: 106031565(TGFB2)
CATA: 118253345(TGFB2)
AFUL: 116488326(TGFB2)
TGU: 100231617(TGFB2)
LSR: 110479104(TGFB2)
SCAN: 103821503(TGFB2)
PMOA: 120496994(TGFB2)
OTC: 121347800(TGFB2)
PRUF: 121358714(TGFB2)
GFR: 102037698(TGFB2)
FAB: 101814341(TGFB2)
OMA: 130251422(TGFB2)
PHI: 102114598(TGFB2)
PMAJ: 107202393(TGFB2)
CCAE: 111926211(TGFB2)
CCW: 104685626(TGFB2)
CBRC: 103612645(TGFB2)
ETL: 114064354(TGFB2)
ZAB: 102066530(TGFB2)
ZLE: 135445923(TGFB2)
ACHL: 103811139(TGFB2)
SVG: 106853582(TGFB2)
MMEA: 130585664(TGFB2)
HRT: 120750747(TGFB2)
SATI: 136359517(TGFB2)
FPG: 101917357(TGFB2)
FCH: 102047778(TGFB2)
CCRI: 104167513
NNT: 104408091(TGFB2)
SHAB: 115613819(TGFB2)
ACUN: 113478516(TGFB2)
TALA: 104357470(TGFB2)
ACHC: 115350306(TGFB2)
HALD: 104319252(TGFB2)
HLE: 104828464(TGFB2)
AGEN: 126052724
GCL: 127014818
CSTI: 104560095(TGFB2)
LDI: 104349792(TGFB2)
MNB: 103769876(TGFB2)
DPUB: 104299873(TGFB2)
AVIT: 104275881(TGFB2)
BRHI: 104499334(TGFB2)
EGZ: 104133428(TGFB2)
NNI: 104019653(TGFB2)
PCRI: 104027607(TGFB2)
PCAO: 104051839(TGFB2)
PADL: 103916133(TGFB2)
AFOR: 103896919(TGFB2)
FGA: 104077136(TGFB2)
GSTE: 104262628(TGFB2)
CLV: 102085196(TGFB2)
MUI: 104537821(TGFB2)
PGUU: 104470023(TGFB2)
PLET: 104619128(TGFB2)
EHS: 104513881(TGFB2)
CMAC: 104483848(TGFB2)
CUCA: 104064807(TGFB2)
TEO: 104383292(TGFB2)
BREG: 104643500(TGFB2)
OHA: 104327864(TGFB2)
ACAR: 104529703(TGFB2)
CPEA: 104386187(TGFB2)
CVF: 104294674(TGFB2)
RTD: 128907397(TGFB2)
AAM: 106490440(TGFB2)
AROW: 112977002(TGFB2)
NPD: 112955150(TGFB2)
TGT: 104569570(TGFB2)
DNE: 112988119(TGFB2)
SCAM: 104140308(TGFB2)
ASN: 102382227(TGFB2)
AMJ: 102562163(TGFB2)
CPOO: 109319735(TGFB2)
GGN: 109296861(TGFB2)
PSS: 102452874(TGFB2)
CMY: 102946116(TGFB2)
CCAY: 125633641(TGFB2)
DCC: 119854030(TGFB2)
CPIC: 101945771(TGFB2)
TST: 117874463(TGFB2)
CABI: 116828212(TGFB2)
MRV: 120402154(TGFB2)
ACS: 100568228(tgfb2)
ASAO: 132761412(TGFB2) 132764403
PVT: 110083352 110087066(TGFB2)
SUND: 121915414 121916287(TGFB2)
PBI: 103063485(TGFB2) 103067099
PMUR: 107293669(TGFB2) 107299193
CTIG: 120297457 120306706(TGFB2) 120317025
TSR: 106538869(TGFB2) 106539344
PGUT: 117656993 117671719(TGFB2)
APRI: 131186500 131189310(TGFB2)
PTEX: 113433267(TGFB2)
NSS: 113421978(TGFB2)
VKO: 123021868(TGFB2) 123032486
PMUA: 114586591 114594660(TGFB2)
PRAF: 128403307 128411119(TGFB2)
ZVI: 118076237 118083182(TGFB2)
HCG: 128336909 128350566(TGFB2)
GJA: 107110247(TGFB2) 107115203
STOW: 125432433(TGFB2) 125436846
EMC: 129325429 129343345(TGFB2)
XLA: 108717706(tgfb2.S) 373801(tgfb2.L)
XTR: 100489680(tgfb2)
NPR: 108795797(TGFB2)
RTEM: 120937894(TGFB2)
BBUF: 120999513(TGFB2)
BGAR: 122934301(TGFB2)
MUO: 115465504(TGFB2) 115480969
GSH: 117357506(TGFB2) 117365102
DRE: 369194(tgfb2) 559723(tgfb2l)
SRX: 107718496 107725266 107737029(tgfb2) 107758502
SANH: 107660799 107689010 107698022 107703928(tgfb2)
SGH: 107559262 107562423(tgfb2) 107589143 107598937
CCAR: 109081563(tgfb2) 109101640 109105720
CAUA: 113045114 113059794(tgfb2) 113113758 113116533
CGIB: 127970925 127974945 128026998 128030893
PTET: 122357923(tgfb5) 122360659(tgfb2)
LROH: 127176018(tgfb5) 127178652(tgfb2)
OMC: 131522136(tgfb2) 131553788(tgfb5)
PPRM: 120460645(tgfb5) 120462707(tgfb2)
RKG: 130084737(tgfb5) 130096578(tgfb2)
MAMB: 125242838(tgfb2) 125275660(tgfb5)
CIDE: 127494595 127496922
CERY: 137018511(tgfb5) 137029998(tgfb2)
MASI: 127412895 127418235 127452537 127453885
TROS: 130549987(tgfb2) 130563435(tgfb5)
TDW: 130433538(tgfb2) 130437978(tgfb5)
MANU: 129422680(tgfb5) 129447838(tgfb2)
IPU: 108268908(tgfb5) 108269996
IFU: 128611433(tgfb5) 128612704(tgfb2)
PHYP: 113526787(tgfb2) 113528823
SMEO: 124385029(tgfb2) 124385821(tgfb5)
TFD: 113636131(tgfb5) 113644518(tgfb2)
TVC: 132845709(tgfb2) 132855840(tgfb5)
TRN: 134310529(tgfb2) 134319310(tgfb5)
AMEX: 103026112(tgfb2) 103042476(tgfb5)
CMAO: 118806906(tgfb5) 118819641(tgfb2)
EEE: 113572191(tgfb2) 113581676
CHAR: 105905499(tgfb2) 105911025(tgfb5)
TRU: 101066787 101074584 115250449
TFS: 130531660(tgfb5) 130532398(tgfb2)
TNG: GSTEN00011872G001 GSTEN00031190G001
LCO: 104925539 104936633(tgfb2)
NCC: 104945388
TBEN: 117470704(tgfb2) 117488821(tgfb5)
CGOB: 115014648 115021567(tgfb2)
PGEO: 117454118(tgfb5) 117460968(tgfb2)
GACU: 117543536(tgfb5) 117555508(tgfb2)
EMAC: 134859818(tgfb5) 134862041(tgfb2)
ELY: 117251444(tgfb5) 117264719(tgfb2)
EFO: 125892868(tgfb2) 125894017(tgfb5)
PLEP: 121946355(tgfb2) 121947966(tgfb5)
SLUC: 116052623(tgfb5) 116064582(tgfb2)
ECRA: 117946043(tgfb2) 117951661(tgfb5)
ESP: 116697037 116699436(tgfb2)
PFLV: 114557393(tgfb2) 114562717
GAT: 120810593(tgfb2) 120817123(tgfb5)
PPUG: 119197865(tgfb2) 119210068(tgfb5)
AFB: 129090050(tgfb5) 129110263(tgfb2)
CLUM: 117728311(tgfb2) 117737528(tgfb5)
PSWI: 130206475(tgfb2) 130209644(tgfb5)
MSAM: 119889077(tgfb5) 119896887(tgfb2)
SCHU: 122880230(tgfb5) 122880976(tgfb2)
CUD: 121515929(tgfb5)
ALAT: 119006720(tgfb2) 119008099(tgfb5)
MZE: 101466107 101469764(tgfb2)
ONL: 100690458 100707856(tgfb2)
OAU: 116317211(tgfb5) 116327679(tgfb2)
OLA: 101155037
OML: 112152993(tgfb5)
CSAI: 133447112(tgfb5)
XMA: 102223216
XCO: 114139436
XHE: 116714966
PRET: 103471446(tgfb2)
PFOR: 103136874 103136935
PLAI: 106936703 106950532(tgfb2)
PMEI: 106915805 106915806
GAF: 122836982(tgfb5)
PPRL: 129362734(tgfb5)
CVG: 107087932(tgfb2)
CTUL: 119784511(tgfb5)
GMU: 124860909(tgfb5)
NFU: 107377547
KMR: 108231423(tgfb5)
ALIM: 106515824
NWH: 119408933(tgfb5)
AOCE: 111569136(tgfb2) 111576372
MCEP: 125008120(tgfb5) 125016524(tgfb2)
CSEM: 103388748(tgfb2) 103390834
POV: 109631969(tgfb2) 109642431
SSEN: 122774279(tgfb2) 122778128(tgfb5)
HHIP: 117769623(tgfb5) 117777108(tgfb2)
HSP: 118112176(tgfb5) 118113442(tgfb2)
PPLT: 128445990(tgfb5) 128449959(tgfb2)
SMAU: 118285006(tgfb2) 118318986(tgfb5)
LCF: 108872574(tgfb5) 108886089
SDU: 111227872(tgfb2) 111232504
SLAL: 111655785 111664155(tgfb2)
XGL: 120784280(tgfb2) 120784927(tgfb5)
HCQ: 109511954 109521921(tgfb2)
SSCV: 125974957 125980128
SBIA: 133500636(tgfb2) 133509095(tgfb5)
PEE: 133401102(tgfb2) 133407580(tgfb5)
PTAO: 133479548(tgfb2) 133484883(tgfb5)
BPEC: 110158948 110159085(tgfb2)
MALB: 109956839 109973033(tgfb2)
BSPL: 114842806(tgfb2) 114864697(tgfb5)
SJO: 128362495(tgfb5) 128365749(tgfb2)
SASA: 106584161 106604392 106605021 106612106
STRU: 115168917 115175550 115177416 115205573
OTW: 112221169(tgfb5) 112223175 112234066(tgfb2) 112255920
OMY: 110489077(tgfb5) 110490140 110519367(tgfb2)
OGO: 123993600(tgfb5) 123998211 124006045(tgfb2)
ONE: 115106696 115130946 115141421
OKI: 109864860 109902227 109910338
OKE: 118364018 118367254 118381108(tgfb5)
SALP: 111965309(tgfb2) 111965954 111967092 112081109
SNH: 120031484 120047387(tgfb5) 120047527 120062054
CCLU: 121536830 121543497 121545895(tgfb5) 121585906
ELS: 105007294(tgfb2) 105026733
SFM: 108925415 108929121(tgfb2)
PKI: 111835201 111851556(tgfb2)
AANG: 118210344(tgfb2) 118222676(tgfb5) 118229069
LOC: 102682814 102683493(tgfb2)
PSPA: 121306334(tgfb5) 121315977 121317109
ARUT: 117398621 117402519 117410435 117962646
PSEX: 120539363(tgfb5)
LCM: 102352268 102358422(TGFB2)
CMK: 103185816(tgfb2)
RTP: 109911779(tgfb2) 109926035(tgfb5)
CPLA: 122552812(tgfb2)
HOC: 132814768 132819744(tgfb2)
LERI: 129699713(tgfb2)
PMRN: 116939388 116947177 116953922
LRJ: 133347010 133356237 133360030
BBEL: 109472278
CIN: 778780(tgfbeta2)
SCLV: 120336447 120336554
SPU: 115929733 588471
LPIC: 129264215
SKO: 100329003(TGFbeta2)
VDE: 111249885
VJA: 111273048
EPA: 110252767 110252794
PDAM: 113671019
AQU: 105312053
 » show all
Reference
PMID:19050695
  Authors
Chen YG
  Title
Endocytic regulation of TGF-beta signaling.
  Journal
Cell Res 19:58-70 (2009)
DOI:10.1038/cr.2008.315
Reference
PMID:15896309
  Authors
Singla DK, Sun B
  Title
Transforming growth factor-beta2 enhances differentiation of cardiac myocytes from embryonic stem cells.
  Journal
Biochem Biophys Res Commun 332:135-41 (2005)
DOI:10.1016/j.bbrc.2005.04.098
  Sequence
[hsa:7042]
Reference
PMID:3322813
  Authors
de Martin R, Haendler B, Hofer-Warbinek R, Gaugitsch H, Wrann M, Schlusener H, Seifert JM, Bodmer S, Fontana A, Hofer E
  Title
Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family.
  Journal
EMBO J 6:3673-7 (1987)
DOI:10.1002/j.1460-2075.1987.tb02700.x
  Sequence
[hsa:7042]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (62)   
   KEGG PATHWAY (62)   
Disease (3)   
   KEGG DISEASE (3)   
Drug (3)   
   KEGG DRUG (3)   
Gene (922)   
   KEGG GENES (578)   
   KEGG MGENES (127)   
   RefGene (213)   
   OC (4)   
Literature (3)   
   PubMed (3)   
All databases (996)   

Download RDF
KEGG   ORTHOLOGY: K13375
Entry
K13375                      KO                                     
Symbol
TGFB1
Name
transforming growth factor beta-1
Pathway
map04010  MAPK signaling pathway
map04060  Cytokine-cytokine receptor interaction
map04068  FoxO signaling pathway
map04110  Cell cycle
map04148  Efferocytosis
map04218  Cellular senescence
map04350  TGF-beta signaling pathway
map04380  Osteoclast differentiation
map04390  Hippo signaling pathway
map04659  Th17 cell differentiation
map04672  Intestinal immune network for IgA production
map04926  Relaxin signaling pathway
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map05140  Leishmaniasis
map05142  Chagas disease
map05144  Malaria
map05145  Toxoplasmosis
map05146  Amoebiasis
map05152  Tuberculosis
map05161  Hepatitis B
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05205  Proteoglycans in cancer
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05220  Chronic myeloid leukemia
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05321  Inflammatory bowel disease
map05323  Rheumatoid arthritis
map05410  Hypertrophic cardiomyopathy
map05414  Dilated cardiomyopathy
map05415  Diabetic cardiomyopathy
Disease
H00083  Allograft rejection
H00084  Graft-versus-host disease
H00218  Cystic fibrosis
H00434  Camurati-Engelmann disease
H02669  Inflammatory bowel disease, immunodeficiency, and encephalopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K13375  TGFB1; transforming growth factor beta-1
   04350 TGF-beta signaling pathway
    K13375  TGFB1; transforming growth factor beta-1
   04390 Hippo signaling pathway
    K13375  TGFB1; transforming growth factor beta-1
   04068 FoxO signaling pathway
    K13375  TGFB1; transforming growth factor beta-1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13375  TGFB1; transforming growth factor beta-1
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K13375  TGFB1; transforming growth factor beta-1
  09143 Cell growth and death
   04110 Cell cycle
    K13375  TGFB1; transforming growth factor beta-1
   04218 Cellular senescence
    K13375  TGFB1; transforming growth factor beta-1
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K13375  TGFB1; transforming growth factor beta-1
   04672 Intestinal immune network for IgA production
    K13375  TGFB1; transforming growth factor beta-1
  09152 Endocrine system
   04926 Relaxin signaling pathway
    K13375  TGFB1; transforming growth factor beta-1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K13375  TGFB1; transforming growth factor beta-1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K13375  TGFB1; transforming growth factor beta-1
   05205 Proteoglycans in cancer
    K13375  TGFB1; transforming growth factor beta-1
  09162 Cancer: specific types
   05210 Colorectal cancer
    K13375  TGFB1; transforming growth factor beta-1
   05212 Pancreatic cancer
    K13375  TGFB1; transforming growth factor beta-1
   05225 Hepatocellular carcinoma
    K13375  TGFB1; transforming growth factor beta-1
   05226 Gastric cancer
    K13375  TGFB1; transforming growth factor beta-1
   05220 Chronic myeloid leukemia
    K13375  TGFB1; transforming growth factor beta-1
   05211 Renal cell carcinoma
    K13375  TGFB1; transforming growth factor beta-1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K13375  TGFB1; transforming growth factor beta-1
   05161 Hepatitis B
    K13375  TGFB1; transforming growth factor beta-1
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K13375  TGFB1; transforming growth factor beta-1
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K13375  TGFB1; transforming growth factor beta-1
   05144 Malaria
    K13375  TGFB1; transforming growth factor beta-1
   05145 Toxoplasmosis
    K13375  TGFB1; transforming growth factor beta-1
   05140 Leishmaniasis
    K13375  TGFB1; transforming growth factor beta-1
   05142 Chagas disease
    K13375  TGFB1; transforming growth factor beta-1
  09163 Immune disease
   05323 Rheumatoid arthritis
    K13375  TGFB1; transforming growth factor beta-1
   05321 Inflammatory bowel disease
    K13375  TGFB1; transforming growth factor beta-1
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K13375  TGFB1; transforming growth factor beta-1
   05414 Dilated cardiomyopathy
    K13375  TGFB1; transforming growth factor beta-1
   05415 Diabetic cardiomyopathy
    K13375  TGFB1; transforming growth factor beta-1
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K13375  TGFB1; transforming growth factor beta-1
   04933 AGE-RAGE signaling pathway in diabetic complications
    K13375  TGFB1; transforming growth factor beta-1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K13375  TGFB1; transforming growth factor beta-1
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K13375  TGFB1; transforming growth factor beta-1
   00536 Glycosaminoglycan binding proteins
    K13375  TGFB1; transforming growth factor beta-1
Chaperones and folding catalysts [BR:ko03110]
 Intramolecular chaperones
  Others
   K13375  TGFB1; transforming growth factor beta-1
Cytokines and neuropeptides [BR:ko04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   K13375  TGFB1; transforming growth factor beta-1
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   K13375  TGFB1; transforming growth factor beta-1
Genes
HSA: 7040(TGFB1)
PTR: 456060(TGFB1)
PPS: 100980947(TGFB1)
GGO: 101124474(TGFB1)
PON: 100459982(TGFB1)
PPYG: 129021011(TGFB1)
NLE: 100581386(TGFB1)
HMH: 116480647(TGFB1)
SSYN: 129466443(TGFB1)
MCC: 106992315(TGFB1)
MCF: 102129546(TGFB1)
MTHB: 126941768
MNI: 105495300(TGFB1)
CSAB: 103234729(TGFB1)
CATY: 105598017(TGFB1)
PANU: 101006627(TGFB1)
TGE: 112612158(TGFB1)
MLEU: 105542552(TGFB1)
RRO: 104676086(TGFB1)
RBB: 108536158(TGFB1)
TFN: 117075968(TGFB1)
PTEH: 111554142(TGFB1)
CANG: 105507882(TGFB1)
CJC: 100401979(TGFB1)
SBQ: 101047980(TGFB1)
CIMI: 108285710(TGFB1)
ANAN: 105723444(TGFB1)
CSYR: 103254633(TGFB1)
MMUR: 105869115(TGFB1)
LCAT: 123624079(TGFB1)
PCOQ: 105820566(TGFB1)
OGA: 100949640(TGFB1)
MMU: 21803(Tgfb1)
MCAL: 110298438(Tgfb1)
MPAH: 110336543(Tgfb1)
RNO: 59086(Tgfb1)
MCOC: 116101857(Tgfb1)
ANU: 117713589(Tgfb1)
MUN: 110561197(Tgfb1)
CGE: 100773359(Tgfb1)
MAUA: 101834601(Tgfb1)
PROB: 127238425(Tgfb1)
PLEU: 114685302(Tgfb1)
MORG: 121449432(Tgfb1)
MFOT: 126494578
AAMP: 119821456(Tgfb1)
NGI: 103751514(Tgfb1)
HGL: 101704230(Tgfb1)
CPOC: 100135628(Tgfb1)
CCAN: 109685632(Tgfb1)
DORD: 106000874(Tgfb1)
DSP: 122097410(Tgfb1)
PLOP: 125338685(Tgfb1)
NCAR: 124967085
MMMA: 107151630(Tgfb1)
OCU: 100008645(TGFB1) 100352301 103345448
OPI: 101529904 101533379(TGFB1)
TUP: 102488524(TGFB1)
GVR: 103599185 103599191
CFA: 403998(TGFB1)
CLUD: 112645426(TGFB1)
VVP: 112928349(TGFB1)
VLG: 121485274(TGFB1)
NPO: 129500810(TGFB1)
AML: 100470703(TGFB1)
UMR: 103677394(TGFB1)
UAH: 113243540(TGFB1)
UAR: 123781846(TGFB1)
ELK: 111161420
LLV: 125089683
MPUF: 101670127(TGFB1)
MNP: 132005078(TGFB1)
MLK: 131817494(TGFB1)
NVS: 122912064(TGFB1)
ORO: 101385166(TGFB1)
EJU: 114202548(TGFB1)
ZCA: 113936424(TGFB1)
MLX: 118022632(TGFB1)
NSU: 110590084(TGFB1)
LWW: 102747528(TGFB1)
FCA: 768263(TGFB1)
PYU: 121018482(TGFB1)
PCOO: 112850697(TGFB1)
PBG: 122494005(TGFB1)
PVIV: 125152868(TGFB1)
LRUF: 124511094
PTG: 102951285(TGFB1)
PPAD: 109257972 109258015
PUC: 125915432
AJU: 106987682
HHV: 120243258(TGFB1)
BTA: 282089(TGFB1)
BOM: 102283357(TGFB1)
BIU: 109572866(TGFB1)
BBUB: 102413660(TGFB1)
BBIS: 104995381(TGFB1)
CHX: 102191364(TGFB1)
OAS: 443417(TGFB1)
BTAX: 128063320(TGFB1)
ODA: 120872413(TGFB1)
CCAD: 122420314(TGFB1)
MBEZ: 129546785(TGFB1)
SSC: 397078(TGFB1)
CFR: 102509937(TGFB1)
CBAI: 105062879(TGFB1)
CDK: 105093367(TGFB1)
VPC: 102539136(TGFB1)
BACU: 103002687(TGFB1)
BMUS: 118885169(TGFB1)
LVE: 103075846(TGFB1)
OOR: 101286197(TGFB1)
DLE: 111180824(TGFB1)
PCAD: 102975643(TGFB1)
PSIU: 116743550(TGFB1)
NASI: 112415266(TGFB1)
ECB: 100033900(TGFB1)
EPZ: 103562543(TGFB1)
EAI: 106843812(TGFB1)
MYB: 102262083(TGFB1)
MYD: 102752983(TGFB1)
MMYO: 118674276(TGFB1)
MLF: 102435068(TGFB1)
MDT: 132216839(TGFB1)
PKL: 118702316(TGFB1)
EFUS: 103284692(TGFB1)
MNA: 107534176(TGFB1)
DRO: 112320009(TGFB1)
SHON: 118982068(TGFB1)
AJM: 119058462(TGFB1)
PDIC: 114510965(TGFB1)
PHAS: 123823713(TGFB1)
MMF: 118638486(TGFB1)
PPAM: 129076675(TGFB1)
HAI: 109376590(TGFB1)
RFQ: 117035087(TGFB1)
PALE: 102884154(TGFB1)
PGIG: 120586591(TGFB1)
PVP: 105307945(TGFB1)
RAY: 107505490(TGFB1)
MJV: 108383720(TGFB1)
TOD: 119248636 119249350(TGFB1)
SARA: 101551346(TGFB1)
SETR: 126028183(TGFB1)
LAV: 100667634(TGFB1)
TMU: 101342543
ETF: 101650988(TGFB1)
DNM: 101437737(TGFB1)
MDO: 100019183(TGFB1)
GAS: 123256028(TGFB1)
SHR: 100932607(TGFB1)
AFZ: 127556228
PCW: 110202366(TGFB1)
TVP: 118838177(TGFB1)
OAA: 114812005(TGFB1)
GGA: 100873157(TGFB1)
PCOC: 116241290
CJO: 107307103(TGFB1)
LSR: 110482796
FAB: 101818496(TGFB1)
OMA: 130266108(TGFB1)
PHI: 102112781(TGFB1)
PMAJ: 107198990(TGFB1)
CCAE: 111942551
ZLE: 135441732(TGFB1)
SHAB: 115603255(TGFB1)
AGEN: 126036615
GCL: 127028058
AROW: 112965764
ASN: 102369002(TGFB1)
AMJ: 102567067(TGFB1)
CMY: 114022153(TGFB1)
CCAY: 125628071(TGFB1)
DCC: 119847152(TGFB1)
CPIC: 101937891(TGFB1)
CABI: 116833884(TGFB1)
MRV: 120388881
ACS: 100553920(tgfb1)
ASAO: 132780051(TGFB1)
PVT: 110088538(TGFB1)
SUND: 121917546 121917598
PBI: 103064413(TGFB1)
PMUR: 107295274(TGFB1)
CTIG: 120319885(TGFB1)
TSR: 106551445(TGFB1)
PGUT: 117677694(TGFB1)
APRI: 131204693(TGFB1)
PTEX: 113445961(TGFB1)
NSS: 113426022(TGFB1)
VKO: 123025913(TGFB1)
PMUA: 114603306(TGFB1)
PRAF: 128418274(TGFB1)
ZVI: 118086683(TGFB1)
HCG: 128332607(TGFB1)
GJA: 107123911(TGFB1)
STOW: 125434165(TGFB1)
EMC: 129343744(TGFB1)
XLA: 108700276(tgfb1.S) 397778(tgfb1.L)
XTR: 100498430(tgfb1)
NPR: 108800768
RTEM: 120913378(TGFB1)
BBUF: 121009227(TGFB1)
BGAR: 122946366 122946419
MUO: 115480705(TGFB1)
GSH: 117365844(TGFB1)
DRE: 359834(tgfb1a) 563884(tgfb1b)
SRX: 107706521 107744019 107745447 107754964
SANH: 107680100 107681095 107703499 107703980
SGH: 107551248 107573058 107589304 107598564
CCAR: 109047284 109055145 109103035 109103040
CAUA: 113038645 113038646 113058184 113064252 113115386
CGIB: 127942123 127973105 127985940 128028714
PTET: 122326853(tgfb1b) 122358909(tgfb1a)
LROH: 127152294(tgfb1b) 127177456(tgfb1a)
OMC: 131520886(tgfb1a) 131528700(tgfb1b)
PPRM: 120465196(tgfb1a) 120490762(tgfb1b)
RKG: 130096464(tgfb1b) 130104467(tgfb1a)
MAMB: 125249338(tgfb1a) 125252540(tgfb1b)
CIDE: 127495355 127503585
CERY: 137004117(tgfb1a) 137012525(tgfb1b)
MASI: 127422282 127428507 127429503 127430733
TROS: 130564574(tgfb1a) 130570154(tgfb1b)
TDW: 130408414(tgfb1b) 130428583(tgfb1a)
MANU: 129423621(tgfb1b) 129437532(tgfb1a)
IPU: 108279384(tgfb1b) 108280750(tgfb1a)
IFU: 128622552(tgfb1b) 128624118(tgfb1a)
PHYP: 113541584 113543081
SMEO: 124397911(tgfb1b) 124402798(tgfb1a)
TFD: 113651967(tgfb1b) 113653216(tgfb1a)
TVC: 132849264(tgfb1a) 132860460(tgfb1b)
TRN: 134302490(tgfb1a) 134330170(tgfb1b)
AMEX: 103024607(tgfb1a) 103033069(tgfb1b)
CMAO: 118796969(tgfb1a) 118819844(tgfb1b)
EEE: 113573801 113590492
CHAR: 105890611 105904460(tgfb1b)
TRU: 101074275(tgf-beta1)
TFS: 130534625(tgfb1a)
TNG: GSTEN00035186G001
LCO: 109141681
NCC: 104950840
TBEN: 117471062(tgfb1a)
CGOB: 115017895
PGEO: 117457172(tgfb1a)
GACU: 117555603(tgfb1a)
ELY: 117259934(tgfb1a)
EFO: 125888922(tgfb1a)
PLEP: 121943219(tgfb1a)
SLUC: 116039943(tgfb1a)
ECRA: 117941999(tgfb1a)
ESP: 116682862
PFLV: 114552362
GAT: 120821525(tgfb1a)
PPUG: 119217376(tgfb1a)
AFB: 129090601(tgfb1a)
CLUM: 117741227(tgfb1a)
PSWI: 130210959(tgfb1a)
MSAM: 119882881(tgfb1a)
SCHU: 122879501(tgfb1a)
CUD: 121521145(tgfb1a)
ALAT: 119009263(tgfb1a)
MZE: 101473892
ONL: 100694653(tgfb1a)
OAU: 116320331(tgfb1a)
OLA: 101157631
OML: 112149754(tgfb1a)
CSAI: 133442009(tgfb1a)
XMA: 102216881
XCO: 114161405
XHE: 116707510
PRET: 103475119
PFOR: 103138264
PLAI: 106947507
PMEI: 106919996
GAF: 122832892(tgfb1a)
PPRL: 129358768(tgfb1a)
CVG: 107103699
CTUL: 119784075(tgfb1a)
GMU: 124884769(tgfb1a)
NFU: 107379821
KMR: 108228916(tgfb1a)
ALIM: 106529655
NWH: 119411428(tgfb1a)
AOCE: 111581736
MCEP: 125013476(tgfb1a)
CSEM: 103377845
POV: 109630415
SSEN: 122773574(tgfb1a)
HHIP: 117772384(tgfb1a)
HSP: 118105944(tgfb1a)
PPLT: 128440037(tgfb1a)
SMAU: 118299716(tgfb1a)
LCF: 108876160(tgfb1a)
SDU: 111216899
SLAL: 111662255
XGL: 120791875(tgfb1a)
HCQ: 109510758
SSCV: 125972061
SBIA: 133504741(tgfb1a)
PEE: 133405086(tgfb1a)
PTAO: 133482292(tgfb1a)
BPEC: 110163549
MALB: 109963227
BSPL: 114867748(tgfb1a)
SJO: 128360542(tgfb1a)
SASA: 100136559(TGFB1) 106563563(TGF-beta) 106613337
STRU: 115154758 115204365 115206692
OTW: 112228884 112231247 112240152
OMY: 100136774 101268942(tgfb1a) 110534057 118936254(tgfb1a)
OGO: 124006497(tgfb1a) 124006978 124007511
ONE: 115101394 115135570
OKI: 109873349 109874437 109882711
OKE: 118381881(tgfb1a) 118385063 118390427
SALP: 111950026 111964258 112070992
SNH: 120021386 120028313(tgfb1a) 120056617
CCLU: 121541234 121541907 121567690 121579543
ELS: 105010856 105027026
SFM: 108924734 108933453
PKI: 111838013 111841476
AANG: 118209403 118236609(tgfb1a)
LOC: 102698936(tgfb1)
PSPA: 121304906
ARUT: 117394578
PSEX: 120538772
LCM: 102364242(TGFB1)
 » show all
Reference
PMID:3470709
  Authors
Derynck R, Rhee L, Chen EY, Van Tilburg A
  Title
Intron-exon structure of the human transforming growth factor-beta precursor gene.
  Journal
Nucleic Acids Res 15:3188-9 (1987)
DOI:10.1093/nar/15.7.3188
  Sequence
[hsa:7040]

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