KEGG   ORTHOLOGY: K13564
Entry
K13564            Tight     KO                                     
Symbol
btrG
Name
gamma-L-glutamyl-butirosin B gamma-L-glutamyl cyclotransferase [EC:4.3.2.6]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R08910  gamma-L-glutamyl-butirosin-B gamma-glutamyl cyclotransferase (5-oxoproline-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K13564  btrG; gamma-L-glutamyl-butirosin B gamma-L-glutamyl cyclotransferase
Enzymes [BR:ko01000]
 4. Lyases
  4.3  Carbon-nitrogen lyases
   4.3.2  Amidine-lyases
    4.3.2.6  gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase
     K13564  btrG; gamma-L-glutamyl-butirosin B gamma-L-glutamyl cyclotransferase
Genes
AG: BAE07071(btrG)
Reference
PMID:16156513
  Authors
Kudo F, Numakura M, Tamegai H, Yamamoto H, Eguchi T, Kakinuma K
  Title
Extended sequence and functional analysis of the butirosin biosynthetic gene cluster in Bacillus circulans SANK 72073.
  Journal
J Antibiot (Tokyo) 58:373-9 (2005)
DOI:10.1038/ja.2005.47
  Sequence
[ag:BAE07071]
Reference
PMID:19362652
  Authors
Kudo F, Eguchi T
  Title
Biosynthetic enzymes for the aminoglycosides butirosin and neomycin.
  Journal
Methods Enzymol 459:493-519 (2009)
DOI:10.1016/S0076-6879(09)04620-5
Reference
PMID:17462573
  Authors
Llewellyn NM, Li Y, Spencer JB
  Title
Biosynthesis of butirosin: transfer and deprotection of the unique amino acid side chain.
  Journal
Chem Biol 14:379-86 (2007)
DOI:10.1016/j.chembiol.2007.02.005
  Sequence
[ag:BAE07071]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (1)   
   KEGG GENES (1)   
Literature (3)   
   PubMed (3)   
All databases (14)   

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