| | ORTHOLOGY: K13755 | |
Entry |
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Symbol |
PDE1
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Name |
calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC: 3.1.4.17]
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Pathway |
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Reaction |
R00191 | adenosine 3',5'-phosphate 5'-nucleotidohydrolase |
R01234 | guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase |
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Disease |
H00604 | Deafness, autosomal dominant |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase
09157 Sensory system
04740 Olfactory transduction
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase
04742 Taste transduction
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase
Enzymes [BR:ko01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Omori K, Kotera J |
Title |
Overview of PDEs and their regulation. |
Journal |
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Sequence |
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Reference |
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Authors |
Loughney K, Martins TJ, Harris EA, Sadhu K, Hicks JB, Sonnenburg WK, Beavo JA, Ferguson K |
Title |
Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases. |
Journal |
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Sequence |
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