KEGG ORTHOLOGY: K13857

ORTHOLOGY: K13857

Entry

K13857                      KO

Symbol

SLC4A5, NBC4

Name

solute carrier family 4 (sodium bicarbonate cotransporter), member 5

Pathway

map04976

Bile secretion

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5
   04147 Exosome
    K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC4: Bicarbonate transporter
   K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5

Other DBs

GO:

0008510

TC:

2.A.31.2

Genes

HSA:	57835(SLC4A5)

PTR:	470408(SLC4A5)

PPS:	100993877(SLC4A5)

GGO:	101141818(SLC4A5)

PON:	100438431(SLC4A5)

PPYG:

129030656(SLC4A5)

NLE:	100584396(SLC4A5)

HMH:	116483871(SLC4A5)

SSYN:

129461723(SLC4A5)

MCC:	715025(SLC4A5)

MCF:	102141597(SLC4A5)

MTHB:

126934010

MNI:	105465287(SLC4A5)

CSAB:

103220036(SLC4A5)

CATY:

105596857(SLC4A5)

PANU:

101014941

TGE:	112604726(SLC4A5)

MLEU:

105540185(SLC4A5)

RRO:	104674808(SLC4A5)

RBB:	108520670(SLC4A5)

TFN:	117062047(SLC4A5)

PTEH:

111523401(SLC4A5)

CANG:

105514590(SLC4A5)

CJC:	100388030(SLC4A5)

SBQ:	101054439(SLC4A5)

CIMI:

108289298(SLC4A5)

ANAN:

105717167(SLC4A5)

CSYR:

103266736(SLC4A5)

MMUR:

105884593(SLC4A5)

LCAT:

123637070(SLC4A5)

PCOQ:

105821495(SLC4A5)

OGA:	100943889(SLC4A5)

MMU:	232156(Slc4a5)

MCAL:

110295879(Slc4a5)

MPAH:

110317402(Slc4a5)

RNO:	297386(Slc4a5)

MCOC:

116099134(Slc4a5)

ANU:	117714861(Slc4a5)

MUN:	110559327(Slc4a5)

CGE:	100771517(Slc4a5)

MAUA:

101843149(Slc4a5)

PROB:

127235812(Slc4a5)

PLEU:

114694413(Slc4a5)

MORG:

121466430(Slc4a5)

MFOT:

126515350

AAMP:

119807178(Slc4a5)

NGI:	103727001(Slc4a5)

HGL:	101705255(Slc4a5)

CPOC:

100714846(Slc4a5)

CCAN:

109676645(Slc4a5)

DORD:

105999580(Slc4a5)

DSP:	122125144(Slc4a5)

PLOP:

125356361(Slc4a5)

NCAR:

124962957

MMMA:

107154213(Slc4a5)

OCU:

100347641

OPI:	101534002(SLC4A5)

TUP:	102475514(SLC4A5)

GVR:	103605418(SLC4A5)

CFA:	612275(SLC4A5)

CLUD:

112664236(SLC4A5)

VVP:	112916727(SLC4A5)

VLG:	121490572(SLC4A5)

NPO:	129501335(SLC4A5)

AML:	100479737(SLC4A5)

UMR:	103671830(SLC4A5)

UAH:	113243796(SLC4A5)

UAR:	123786131(SLC4A5)

ELK:

111147980

LLV:

125108919

MPUF:

101672487(SLC4A5)

MNP:	132021438(SLC4A5)

MLK:	131840319(SLC4A5)

NVS:	122915001(SLC4A5)

ORO:	101375841(SLC4A5)

EJU:	114218946(SLC4A5)

ZCA:	113937925(SLC4A5)

MLX:	118007959(SLC4A5)

NSU:	110588690(SLC4A5)

LWW:	102726407(SLC4A5)

FCA:	101084098(SLC4A5)

PYU:

121019228

PCOO:

112868885(SLC4A5)

PBG:	122497030(SLC4A5)

PVIV:

125162719(SLC4A5)

LRUF:

124504215

PTG:	102961396(SLC4A5)

PPAD:

109263054(SLC4A5)

PUC:

125937123

AJU:

106988573

HHV:	120237015(SLC4A5)

BTA:	100297538(SLC4A5)

BOM:	102279361(SLC4A5)

BIU:	109565919(SLC4A5)

BBUB:

102395891(SLC4A5)

BBIS:

104980992(SLC4A5)

CHX:	102183881(SLC4A5)

OAS:	101105902(SLC4A5)

BTAX:

128056715(SLC4A5)

ODA:	120851235(SLC4A5)

CCAD:

122441492(SLC4A5)

MBEZ:

129539333(SLC4A5)

SSC:	100620628(SLC4A5)

CFR:	102522605(SLC4A5)

CBAI:

105066982(SLC4A5)

CDK:	105096570(SLC4A5)

VPC:	102542786(SLC4A5)

BACU:

103000129(SLC4A5)

BMUS:

118906214(SLC4A5)

LVE:	103080314(SLC4A5)

OOR:	101271534(SLC4A5)

DLE:	111169133(SLC4A5)

PCAD:

102977333(SLC4A5)

PSIU:

116764226(SLC4A5)

NASI:

112413639(SLC4A5)

ECB:	100069223(SLC4A5)

EPZ:	103564985(SLC4A5)

EAI:	106823851(SLC4A5)

MYB:	102257933(SLC4A5)

MYD:	102754513(SLC4A5)

MMYO:

118668840(SLC4A5)

MLF:	102435142(SLC4A5)

MDT:	132213197(SLC4A5)

PKL:	118717555(SLC4A5)

EFUS:

103291408(SLC4A5)

MNA:	107529262(SLC4A5)

DRO:	112303008(SLC4A5)

SHON:

119000083(SLC4A5)

AJM:	119038409(SLC4A5)

PDIC:

114498522(SLC4A5)

PHAS:

123811403(SLC4A5)

MMF:	118630676(SLC4A5)

PPAM:

129086853(SLC4A5)

HAI:	109371224(SLC4A5)

RFQ:	117033401(SLC4A5)

PALE:

102885219(SLC4A5)

PGIG:

120594385(SLC4A5)

PVP:	105290774(SLC4A5)

RAY:	107502904(SLC4A5)

MJV:	108402281(SLC4A5)

TOD:	119259085(SLC4A5)

SARA:

101558257(SLC4A5)

SETR:

126023962(SLC4A5)

LAV:	100672155(SLC4A5)

TMU:

101348815

ETF:	101655912(SLC4A5)

DNM:	101438069(SLC4A5)

MDO:	100024265(SLC4A5)

GAS:	123233068(SLC4A5)

SHR:	100917647(SLC4A5)

AFZ:

127547315

PCW:	110222648(SLC4A5)

TVP:	118841814(SLC4A5)

OAA:	100090321(SLC4A5)

GGA:	425261(SLC4A5)

PCOC:

116234501(SLC4A5)

MGP:	100538833(SLC4A5)

CJO:	107323668(SLC4A5)

TPAI:

128071848(SLC4A5)

LMUT:

125685162(SLC4A5)

NMEL:

110387223(SLC4A5)

APLA:

119713565(SLC4A5)

ACYG:

106047655(SLC4A5)

CATA:

118259343(SLC4A5)

AFUL:

116499380(SLC4A5)

TGU:	100219965(SLC4A5)

LSR:	110480189(SLC4A5)

SCAN:

103824668(SLC4A5)

PMOA:

120499128(SLC4A5)

OTC:	121336007(SLC4A5)

PRUF:

121355598(SLC4A5)

GFR:	102034816(SLC4A5)

FAB:	101815490(SLC4A5)

OMA:	130261913(SLC4A5)

PHI:	102104673(SLC4A5)

PMAJ:

107199104

CCAE:

111938874(SLC4A5)

CCW:	104683767(SLC4A5)

CBRC:

103622618(SLC4A5)

ETL:	114070889(SLC4A5)

ZLE:	135456949(SLC4A5)

ACHL:

103804525(SLC4A5)

SVG:	106862869(SLC4A5)

MMEA:

130586953

HRT:	120764001(SLC4A5)

SATI:

136372444(SLC4A5)

FPG:	101914098(SLC4A5)

FCH:	102045688(SLC4A5)

NNT:	104405972(SLC4A5)

SHAB:

115618517(SLC4A5)

ACUN:

113488112

TALA:

104361408(SLC4A5)

ACHC:

115350460(SLC4A5)

HALD:

104321287(SLC4A5)

HLE:	104829016(SLC4A5)

AGEN:

126051736

GCL:

127025373

LDI:

104348408

DPUB:

104297833(SLC4A5)

BRHI:

104494451(SLC4A5)

EGZ:	104130379(SLC4A5)

PCRI:

104029425(SLC4A5)

PCAO:

104050744

PADL:

103917168(SLC4A5)

AFOR:

103903697(SLC4A5)

FGA:	104074612(SLC4A5)

CLV:	102087695(SLC4A5)

PGUU:

104472051

EHS:	104511919(SLC4A5)

CMAC:

104486459(SLC4A5)

CUCA:

104067020

TEO:	104376180(SLC4A5)

BREG:

104637905(SLC4A5)

OHA:	104338079(SLC4A5)

CPEA:

104394350(SLC4A5)

CVF:	104281774(SLC4A5)

RTD:	128900128(SLC4A5)

AAM:	106484146 106498063

AROW:

112975334(SLC4A5)

NPD:	112950585(SLC4A5)

TGT:	104580415(SLC4A5)

DNE:	112993856(SLC4A5)

SCAM:

104150774(SLC4A5)

ASN:	102379950(SLC4A5)

AMJ:	102576439(SLC4A5)

CPOO:

109317356(SLC4A5)

GGN:	109295503(SLC4A5)

PSS:	102448268(SLC4A5)

CMY:	102945669(SLC4A5)

CCAY:

125626364(SLC4A5)

DCC:	119848607(SLC4A5)

CPIC:

101931632(SLC4A5)

TST:	117872893(SLC4A5)

CABI:

116821201(SLC4A5)

MRV:	120397398(SLC4A5)

ACS:

100563636

ASAO:

132782372(SLC4A5)

PVT:	110072090(SLC4A5)

SUND:

121934315(SLC4A5)

PBI:	103051739(SLC4A5)

PMUR:

107283232(SLC4A5)

CTIG:

120299358(SLC4A5)

TSR:	106544035(SLC4A5)

PGUT:

117673330(SLC4A5)

APRI:

131204053(SLC4A5)

PTEX:

113445767(SLC4A5)

NSS:	113423395(SLC4A5)

VKO:	123016774(SLC4A5)

PMUA:

114602654(SLC4A5)

PRAF:

128420064(SLC4A5)

ZVI:	118086869(SLC4A5)

HCG:	128333756(SLC4A5)

GJA:	107118733(SLC4A5)

STOW:

125442050(SLC4A5)

EMC:	129342037(SLC4A5)

XLA:	108710312(slc4a5.L)

XTR:	100494100(slc4a5)

NPR:	108793887(SLC4A5)

RTEM:

120930248 120931051(SLC4A5)

BBUF:

120987187(SLC4A5)

BGAR:

122929524(SLC4A5)

MUO:	115469294(SLC4A5)

GSH:	117362499(SLC4A5)

DRE:	100006379(slc4a5) 559268(si:ch211-48m9.1)

SRX:	107706806 107709849 107721547 107741653

SANH:

107656495 107673401 107689609

SGH:	107567746 107587309 107588954 107595028

CCAR:

109081111

CAUA:

113069974 113079333 113110328

CGIB:

127958233 127966852 128009568

PTET:

122333761(slc4a5b) 122345751(slc4a5a)

LROH:

127165573(slc4a5a) 127172316(slc4a5b)

OMC:	131540295(slc4a5a) 131547888(slc4a5b)

PPRM:

120469921(slc4a5a) 120482551(slc4a5b)

RKG:	130089844(slc4a5a) 130094912(slc4a5b)

MAMB:

125262396(slc4a5b) 125266519(slc4a5a)

CIDE:

127513669 127520188

CERY:

137028554(slc4a5b)

MASI:

127429159 127432364 127432562 127433863

TROS:

130545971(slc4a5b) 130567997(slc4a5a)

TDW:	130411623(slc4a5b) 130419223(slc4a5a)

MANU:

129440114(slc4a5a) 129446470(slc4a5b)

IPU:	108255867(slc4a5a) 108276580(slc4a5b)

IFU:	128620283(slc4a5b) 128625712(slc4a5a)

PHYP:

113542561 113544904

SMEO:

124380818(slc4a5a) 124393494(slc4a5b)

TFD:	113638478(slc4a5b) 113638960(slc4a5a)

TVC:	132854900(slc4a5a) 132863343(slc4a5b)

TRN:	134332927(slc4a5b) 134335522(slc4a5a)

AMEX:

103038731(slc4a5a) 103042590(slc4a5b)

CMAO:

118824430(slc4a5b) 118827483(slc4a5a)

EEE:	113583909 113589570

CHAR:

105889877(slc4a5a) 105904677(slc4a5b)

TRU:	101071760 101072168

TFS:	130517202(slc4a5b) 130526248(slc4a5a)

TNG:	GSTEN00025388G001 GSTEN00034894G001

LCO:	104938766 109139920

TBEN:

117468668 117480859(slc4a5a)

CGOB:

115013463 115016446

PGEO:

117452649(slc4a5a)

GACU:

117536290(slc4a5a)

EMAC:

134868503(slc4a5b) 134873086(slc4a5a)

ELY:	117252910(slc4a5a) 117269623(slc4a5b)

EFO:	125889998(slc4a5a) 125906328(slc4a5b)

PLEP:

121943956(slc4a5a)

SLUC:

116041773(slc4a5b) 116047652(slc4a5a)

ECRA:

117944661(slc4a5a) 117959734

ESP:	116686199 116689516

PFLV:

114555340 114571048

GAT:	120830200(slc4a5a)

PPUG:

119224425(slc4a5a) 119226658(slc4a5b)

AFB:	129101623(slc4a5a) 129102879(slc4a5b)

CLUM:

117735871(slc4a5a) 117740686(slc4a5b)

PSWI:

130197442(slc4a5a) 130205527

MSAM:

119891426(slc4a5a) 119914969 119915080(slc4a5b)

SCHU:

122865668 122877024(slc4a5a)

CUD:	121509779(slc4a5a) 121525355(slc4a5b)

ALAT:

119019552(slc4a5a) 119030448(slc4a5b)

MZE:	101470466 101477060

ONL:	100700344 100703988

OAU:	116321089(slc4a5a) 116329326(slc4a5b)

OLA:	101162225 101171498

OML:	112148833(slc4a5a) 112162984(slc4a5b)

CSAI:

133451447(slc4a5a) 133455149(slc4a5b)

XMA:	102219504 102223050

XCO:	114150209 114154324

XHE:	116724727 116730214

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122819247(slc4a5b) 122826256(slc4a5a)

PPRL:

129373020(slc4a5a) 129379776(slc4a5b)

CVG:	107101937 107102242(slc4a5)

CTUL:

119781488(slc4a5a) 119795963(slc4a5b)

GMU:	124872671(slc4a5b) 124877602(slc4a5a)

NFU:	107393817(slc4a5) 107395321

KMR:	108245384(slc4a5b) 108246431(slc4a5a)

ALIM:

106521938 106526085

NWH:	119412955(slc4a5a) 119424939(slc4a5b)

AOCE:

111574432 111577488

MCEP:

124996463(slc4a5b) 125012573(slc4a5a)

CSEM:

103389646 103397421(slc4a5)

POV:	109626033 109633668

SSEN:

122758313 122769857(slc4a5a)

HHIP:

117768209(slc4a5a) 117771879(slc4a5b)

HSP:	118098129(slc4a5b) 118115390(slc4a5a)

PPLT:

128425002(slc4a5b) 128438222(slc4a5a)

SMAU:

118300652(slc4a5b) 118314535(slc4a5a)

LCF:	108878044 108891291 108895500(slc4a5b)

SDU:	111226170(slc4a5) 111239671

SLAL:

111648002 111659483

XGL:	120805119(slc4a5a) 120806362(slc4a5b)

HCQ:	109525055 109527912

SSCV:

125979476 125994290

SBIA:

133490850 133500022(slc4a5a)

PEE:	133400336(slc4a5a) 133413365(slc4a5b)

PTAO:

133474747(slc4a5a) 133490169(slc4a5b)

BPEC:

110163291(slc4a5) 110166695

MALB:

109974745

BSPL:

114862428(slc4a5a) 114866496(slc4a5b)

SJO:	128365471(slc4a5a) 128379909

SASA:

106562986 106568526 106580514 106585121

STRU:

115159783 115164277 115199651 115203874

OTW:	112219923 112231497 112248670 112266094

OMY:	110509317 110522819 110526893(slc4a5a) 110535095

OGO:	124007420 124036500 124049128

ONE:	115101060 115111790 115140692

OKI:	109868818 109873929 109880103 109894932

OKE:	118357878 118373301 118385571 118393411

SALP:

111957560 111974357

SNH:	120021857 120025853 120051470 120062912

CCLU:

121530667 121541505 121582689 121585040

ELS:	105015229 105029382

SFM:	108930029 108940366 114910715

PKI:	111848581(slc4a5) 111851460

AANG:

118213162(slc4a5b) 118237211(slc4a5a)

LOC:	102682547(slc4a5)

PSPA:

121303199

ARUT:

117397864 117966474

PSEX:

120538869(slc4a5a)

LCM:

RTP:

CPLA:

HOC:

LERI:

TCF:

Reference

PMID:18588858

Authors

Millar ID, Brown PD

Title

NBCe2 exhibits a 3 HCO3(-):1 Na+ stoichiometry in mouse choroid plexus epithelial cells.

Journal

Biochem Biophys Res Commun 373:550-4 (2008)
DOI:10.1016/j.bbrc.2008.06.053

Reference

PMID:23589833

Authors

Parker MD, Boron WF

Title

The divergence, actions, roles, and relatives of sodium-coupled bicarbonate transporters.

Journal

Physiol Rev 93:803-959 (2013)
DOI:10.1152/physrev.00023.2012

Sequence

[hsa:57835]

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   TC (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (1485)   
   KEGG GENES (527)   
   KEGG MGENES (449)   
   RefGene (505)   
   OC (4)   
Literature (2)   
   PubMed (2)   
All databases (1494)   

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