KEGG   ORTHOLOGY: K13937Help
Entry
K13937                      KO                                     

Name
H6PD
Definition
hexose-6-phosphate dehydrogenase [EC:1.1.1.47 3.1.1.31]
Pathway
ko00030  Pentose phosphate pathway
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01200  Carbon metabolism
Module
M00004  Pentose phosphate pathway (Pentose phosphate cycle)
M00006  Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
Disease
H01111  Cortisone reductase deficiency (CRD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Carbohydrate metabolism
   00030 Pentose phosphate pathway
    K13937  H6PD; hexose-6-phosphate dehydrogenase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00004  Pentose phosphate pathway (Pentose phosphate cycle)
     K13937  H6PD; hexose-6-phosphate dehydrogenase
    M00006  Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
     K13937  H6PD; hexose-6-phosphate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.47  glucose 1-dehydrogenase [NAD(P)+]
     K13937  H6PD; hexose-6-phosphate dehydrogenase
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.31  6-phosphogluconolactonase
     K13937  H6PD; hexose-6-phosphate dehydrogenase
BRITE hierarchy
Other DBs
RN: R02035 R02736
GO: 0047936 0017057
Genes
HSA: 9563(H6PD)
PTR: 100610187(H6PD)
PPS: 100993268(H6PD)
GGO: 101142424(H6PD)
PON: 100439160(H6PD)
NLE: 100588208(H6PD)
MCC: 710107(H6PD)
MCF: 102115057(H6PD)
CSAB: 103225643(H6PD)
RRO: 104663055(H6PD)
RBB: 108517948(H6PD)
CJC: 100386191(H6PD)
SBQ: 101028058(H6PD)
MMU: 100198(H6pd)
RNO: 298655(H6pd)
CGE: 100770090(H6pd)
NGI: 103733152(H6pd)
HGL: 101715539(H6pd)
CCAN: 109682341(H6pd)
OCU: 100357500(H6PD)
TUP: 102502621(H6PD)
CFA: 489642(H6PD)
AML: 100476557(H6PD)
UMR: 103666677(H6PD)
ORO: 101384136(H6PD)
FCA: 101098066(H6PD)
PTG: 102961280(H6PD)
AJU: 106984893(H6PD)
BOM: 102267212(H6PD)
BIU: 109570359(SPSB1)
PHD: 102329249
CHX: 102174863(H6PD)
OAS: 101114124(H6PD)
SSC: 110261091(H6PD)
CFR: 102515995(H6PD)
CDK: 105106995(H6PD)
BACU: 103015524(H6PD)
LVE: 103083939(H6PD)
OOR: 101277991(H6PD)
ECB: 100057646(H6PD)
EPZ: 103549083(H6PD)
EAI: 106826224(H6PD)
MYB: 102257733(H6PD)
MYD: 102767216(H6PD)
HAI: 109381286(H6PD)
RSS: 109455276(H6PD)
PALE: 102883153(H6PD)
LAV: 100663707(H6PD)
TMU: 101347869
MDO: 100009940(H6PD)
SHR: 100924302(H6PD)
OAA: 100082409
GGA: 428188(H6PD)
MGP: 100545189(H6PD)
CJO: 107323555(H6PD)
APLA: 101804195(H6PD)
ACYG: 106044323(H6PD)
TGU: 100228049(H6PD)
GFR: 102045426(H6PD)
FAB: 101813192(H6PD)
PHI: 102103089(H6PD)
PMAJ: 107213774(H6PD)
CCW: 104693331(H6PD)
FPG: 101919545(H6PD)
FCH: 102049461(H6PD)
CLV: 102095298(H6PD)
EGZ: 104133127(H6PD)
AAM: 106499029(H6PD)
ASN: 102369764(H6PD)
AMJ: 102562599(H6PD)
PSS: 102461733(H6PD)
CMY: 102932628(H6PD)
CPIC: 101951423(H6PD)
ACS: 100551772(h6pd)
PVT: 110073255(H6PD)
PBI: 103060486(H6PD)
GJA: 107110280(H6PD)
XTR: 100127695(h6pd)
NPR: 108787846(H6PD)
DRE: 569348(h6pd)
SGH: 107555977(h6pd)
CCAR: 109058644
IPU: 108271794(h6pd)
AMEX: 103045767(h6pd)
TRU: 101073312(h6pd)
LCO: 104920493(h6pd)
NCC: 104956358(h6pd)
MZE: 101464302(h6pd)
OLA: 101167199(h6pd)
XMA: 102223104(h6pd)
PRET: 103464522(h6pd)
NFU: 107385214(h6pd)
CSEM: 103385698(h6pd)
LCF: 108889991(h6pd)
HCQ: 109510667(h6pd)
BPEC: 110168637(h6pd)
ELS: 105025428(h6pd)
SFM: 108933884(h6pd)
LCM: 102349672(H6PD)
CMK: 103184186(h6pd)
SPU: 590387(h6pd)
APLC: 110983992
SKO: 100372939(H6PD)
CRG: 105340439
MYI: 110446859
OBI: 106867532
LAK: 106166073
EPA: 110254168
ADF: 107345186
AQU: 105314200
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Clarke JL, Mason PJ
  Title
Murine hexose-6-phosphate dehydrogenase: a bifunctional enzyme with broad substrate specificity and 6-phosphogluconolactonase activity.
  Journal
Arch Biochem Biophys 415:229-34 (2003)
DOI:10.1016/S0003-9861(03)00229-7
Reference
  Authors
Mason PJ, Stevens D, Diez A, Knight SW, Scopes DA, Vulliamy TJ
  Title
Human hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) encoded at 1p36: coding sequence and expression.
  Journal
Blood Cells Mol Dis 25:30-7 (1999)
DOI:10.1006/bcmd.1999.0224
  Sequence
[hsa:9563]

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