KEGG   ORTHOLOGY: K13940
Entry
K13940                      KO                                     

Name
sulD
Definition
dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:4.1.2.25 2.7.6.3]
Pathway
ko00790  Folate biosynthesis
ko01100  Metabolic pathways
ko01240  Biosynthesis of cofactors
Module
M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    K13940  sulD; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.6  Diphosphotransferases
    2.7.6.3  2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
     K13940  sulD; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.2  Aldehyde-lyases
    4.1.2.25  dihydroneopterin aldolase
     K13940  sulD; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
Other DBs
RN: R03503 R03504
COG: COG1539 COG0801
GO: 0004150 0003848
Genes
NBA: CUN60_09500(folK)
GUR: Gura_0703
PACA: ID47_10005
DEA: FPZ08_06550(folK)
CON: TQ29_12370
SALO: EF888_20715(folK)
GOX: GOX1536
GOH: B932_0500
GOY: GLS_c16640(sulD)
GAL: A0U94_01835
GTI: FXF46_08070(folK)
ABG: Asbog_00294(folK)
NTN: D5366_07555(folK)
NEH: E3E11_03040(folB)
SSAM: E3D00_02490(folK)
SWF: E3E12_03365(folK)
BOB: GN304_00995(folK)
BOMB: GT348_07620(folK)
SPN: SP_0292(sulD)
SPD: SPD_0272(sulD)
SPR: spr0269(sulD)
SPW: SPCG_0305(sulD)
SJJ: SPJ_0301
SPX: SPG_0277(sulD)
SNT: SPT_0338
SND: MYY_0371
SPNN: T308_01445
SPV: SPH_0409
SNC: HMPREF0837_10608(folK)
SPP: SPP_0342
SPNG: HMPREF1038_00348(sulD)
SNP: SPAP_0339
SSA: SSA_0200(folK)
SGO: SGO_1912
SMB: smi_0282(sulD)
SOR: SOR_0229(sulD)
SCP: HMPREF0833_11668(folK)
SCF: Spaf_0298(folK)
STRN: SNAG_0296(sulD)
SKI: D7D50_01980(folK)
SGW: D7D53_07795(folB)
CAC: CA_C2927(folA_folK)
CAE: SMB_G2963(folA_folK)
CAY: CEA_G2934(folA)
CPE: CPE1022
CPF: CPF_1277(folBK)
CPR: CPR_1099(folBK)
CBA: CLB_0871(folK)
CBH: CLC_0885(folK)
CBY: CLM_0973(folK)
CBL: CLK_0232(folK)
CBB: CLD_3742(folK)
CBI: CLJ_B0872(folK)
CBF: CLI_0912(folK)
CBM: CBF_0883(folK)
CBE: Cbei_0207
CBZ: Cbs_0207
CBEI: LF65_00245
CKL: CKL_0960
CKR: CKR_0868
CSR: Cspa_c02580(folK)
CPAS: Clopa_0290
CPAT: CLPA_c02240(sulD)
CPAE: CPAST_c02240(sulD)
CBV: U729_1957(folB)
CSQ: CSCA_3675
CLD: CLSPO_c08300(sulD)
CTYK: CTK_C11620
CDY: F3K33_01200(folK)
HHW: NCTC503_01068(sulD)
CALE: FDN13_03690(folK)
SARJ: HH195_06075(folK)
RCH: RUM_01180
RUM: CK1_08030
COO: CCU_11740
CCOM: I6K69_14280(folK)
BPRO: PMF13cell1_02147(sulD)
BLAB: EYS05_15345(folK)
CSCI: HDCHBGLK_03410(sulD)
BPRL: CL2_10190
ACAC: EYQ97_13135(folK)
EHL: EHLA_1304
ANR: Ana3638_20095(folK)
RTO: RTO_04700
HMO: HM1_0669(folB)
HCV: FTV88_2661(folB)
ELM: ELI_3369
AWO: Awo_c10910(folBK)
AMIC: Ami3637_00965(folK)
ADG: Adeg_1882
TOC: Toce_0573
FMA: FMG_0880
PMIC: NW74_05960
PHAR: NCTC13077_01641(sulD)
KPAR: JL105_06565(folK)
MFUN: GXM21_05475(folK)
AIN: Acin_1455(folK)
PFAC: PFJ30894_01388(sulD)
CKP: ckrop_1648(folXK)
CMI: CMM_0848(folBK)
CMS: CMS0103
CMC: CMN_00808(folBK)
HEA: HL652_00690(folB)
AAI: AARI_00870(folBK)
GLU: F0M17_00400(folK)
BCV: Bcav_0705
BSAU: DWV08_03675(folK)
DAY: FV141_11965(folK)
LMOI: VV02_23135
XCE: Xcel_2984
IDO: I598_3015(folK)
XYA: ET471_03330(folK)
SANW: G7063_12795(folK)
CFL: Cfla_0630
CFI: Celf_0562
CELZ: E5225_14700(folK)
CEJ: GC089_15705(folK)
CELH: GXP71_19235(folK)
OEK: FFI11_000510(folK)
JLI: EXU32_01570(folK)
JME: EEW87_002600(folK)
TEH: GKE56_11335(folK)
PHW: G7075_19650(folK)
PEI: H9L10_10935(folK)
SERJ: SGUI_1464
SERW: FY030_01750(folK)
ORN: DV701_14530(folB)
ORZ: FNH13_17420(folK)
BLIN: BLSMQ_1002
BRI: FDF13_00980(folK)
BLUT: EW640_13760(folK)
BCAU: I6G59_08110(folK)
DCO: SAMEA4475696_0663(sulD)
AUS: IPK37_03185(folK)
GEZ: FE251_13925(folK)
HALT: IM660_03660(folK)
NDA: Ndas_4974
ACE: Acel_0208
AHE: Arch_0254
ARCA: HC352_01240(folK)
MCU: HMPREF0573_10365(folK)
TPYO: X956_08610
TBW: NCTC13354_01377(folK)
SOO: FBF35_01595(folK)
AIR: NCTC12972_01539(folB)
ASLA: NCTC11923_01005(folB)
FSL: EJO69_06705(folK)
FLH: EJ997_07650(folK)
WIK: H8R18_07990(folK)
BLO: BL1685(sulD)
BLJ: BLD_1852(folB)
BLN: Blon_0552
BLON: BLIJ_0556
BLF: BLIF_1645
BLL: BLJ_1628
BLB: BBMN68_1719(folB)
BLM: BLLJ_1576
BLG: BIL_03030
BAD: BAD_0412(sulD)
BADL: BADO_0417
BLA: BLA_0475(sulD)
BBB: BIF_00485
BBC: BLC1_0477
BLV: BalV_0478
BLW: W7Y_0502
BLS: W91_0517
BANI: Bl12_0462
BANL: BLAC_02520
BANM: EN10_02550
BDE: BDP_0552
BDN: BBDE_0526
BBP: BBPR_1442(sulD)
BBI: BBIF_1385(folK)
BBF: BBB_1418(folK)
BBV: HMPREF9228_1544(folK)
BBRU: Bbr_1493(sulD)
BBRE: B12L_1417
BBRV: B689b_1528
BBRJ: B7017_1689
BBRC: B7019_1689
BBRN: B2258_1473
BBRS: BS27_1517(sulD)
BBRD: BBBR_1531
BAST: BAST_1242
BCOR: BCOR_1077
BKS: BBKW_0445
BCAT: BBCT_0393
BPSP: AH67_02775
BANG: BBAG_0309
BPSC: BBPC_0439
BSCA: BBSC_0624
SIJ: SCIP_0423
PDO: PSDT_1121
AYM: YM304_16820(sulD)
TTF: THTE_4191
FMR: Fuma_06393(sulD)
PBU: L21SP3_01032(folK)
PBP: STSP1_01094(folK)
ALUS: STSP2_02189(folK)
FNU: FN0072
FNF: BSQ88_06675(folK)
ALD: GFH31_08540(folK)
DORI: FH5T_11295
FLS: GLV81_09145(folK)
LACS: H4075_07830(folK)
MGOT: MgSA37_03414(sulD)
MGIN: FRZ54_20480(folK)
ALS: DJ013_10920(folK)
CJG: NCTC13459_01260(sulD)
CCAS: EIB73_06220(folK)
CANT: NCTC13489_01276(sulD)
KDA: EIB71_11295(folK)
TMW: THMA_0037
TMQ: THMB_0037
TMX: THMC_0037
TRQ: TRQ2_0904
TNA: CTN_0650
TNP: Tnap_0672
TYE: THEYE_A1015(folK)
 » show all
Reference
  Authors
Garcon A, Levy C, Derrick JP
  Title
Crystal structure of the bifunctional dihydroneopterin aldolase/6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Streptococcus pneumoniae.
  Journal
J Mol Biol 360:644-53 (2006)
DOI:10.1016/j.jmb.2006.05.038
  Sequence
[spr:spr0269]

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