KEGG   ORTHOLOGY: K14245
Entry
K14245            Tight     KO                                     
Symbol
auaC
Name
PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00848  Aurachin biosynthesis, anthranilate => aurachin A
Reaction
R12049  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K14245  auaC; PKS ketosynthase (KS/KS alpha)
Other DBs
COG: COG0304
UniProt: P43678 Q3S8R4
Genes
AG: CAL48955(auaC)
Reference
  Authors
Pistorius D, Li Y, Mann S, Muller R
  Title
Unprecedented anthranilate priming involving two enzymes of the acyl adenylating superfamily in aurachin biosynthesis.
  Journal
J Am Chem Soc 133:12362-5 (2011)
DOI:10.1021/ja203653w
  Sequence
Reference
  Authors
Sandmann A, Dickschat J, Jenke-Kodama H, Kunze B, Dittmann E, Muller R
  Title
A Type II polyketide synthase from the gram-negative Bacterium Stigmatella aurantiaca is involved in Aurachin alkaloid biosynthesis.
  Journal
Angew Chem Int Ed Engl 46:2712-6 (2007)
DOI:10.1002/anie.200603513

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