KEGG   ORTHOLOGY: K14254
Entry
K14254                      KO                                     
Symbol
oxyQ
Name
aminotransferase
Pathway
map00253  Tetracycline biosynthesis
map01057  Biosynthesis of type II polyketide products
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00780  Tetracycline/oxytetracycline biosynthesis, pretetramide => tetracycline/oxytetracycline
M00823  Chlortetracycline biosynthesis, pretetramide => chlortetracycline
Reaction
R09197  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K14254  oxyQ; aminotransferase
   00253 Tetracycline biosynthesis
    K14254  oxyQ; aminotransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K14254  oxyQ; aminotransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Others
   K14254  oxyQ; aminotransferase
Genes
SVR: CP971_23970(dapC)
SRIM: CP984_02450(dapC)
SPLA: CP981_34455(dapC)
KAU: B6264_18545
ACTU: Actkin_02498(dapL)
DAUR: Daura_37945(dapC)
AG: AAZ78340(oxyQ)
Reference
PMID:16597959
  Authors
Zhang W, Ames BD, Tsai SC, Tang Y
  Title
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.
  Journal
Appl Environ Microbiol 72:2573-80 (2006)
DOI:10.1128/AEM.72.4.2573-2580.2006
  Sequence
[ag:AAZ78340]
Reference
PMID:20522541
  Authors
Pickens LB, Tang Y
  Title
Oxytetracycline biosynthesis.
  Journal
J Biol Chem 285:27509-15 (2010)
DOI:10.1074/jbc.R110.130419
Reference
PMID:18422316
  Authors
Zhang W, Watanabe K, Cai X, Jung ME, Tang Y, Zhan J
  Title
Identifying the minimal enzymes required for anhydrotetracycline biosynthesis.
  Journal
J Am Chem Soc 130:6068-9 (2008)
DOI:10.1021/ja800951e

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (8)   
   KEGG MODULE (2)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (8)   
   KEGG GENES (7)   
   OC (1)   
Literature (3)   
   PubMed (3)   
All databases (25)   

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