KEGG   ORTHOLOGY: K14272Help
Entry
K14272                      KO                                     

Name
GGAT
Definition
glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44]
Pathway
ko00220  Arginine biosynthesis
ko00250  Alanine, aspartate and glutamate metabolism
ko00260  Glycine, serine and threonine metabolism
ko00630  Glyoxylate and dicarboxylate metabolism
ko00710  Carbon fixation in photosynthetic organisms
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01130  Biosynthesis of antibiotics
ko01200  Carbon metabolism
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00171  C4-dicarboxylic acid cycle, NAD - malic enzyme type
M00532  Photorespiration
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K14272  GGAT; glutamate--glyoxylate aminotransferase
  09102 Energy metabolism
   00710 Carbon fixation in photosynthetic organisms
    K14272  GGAT; glutamate--glyoxylate aminotransferase
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K14272  GGAT; glutamate--glyoxylate aminotransferase
   00260 Glycine, serine and threonine metabolism
    K14272  GGAT; glutamate--glyoxylate aminotransferase
   00220 Arginine biosynthesis
    K14272  GGAT; glutamate--glyoxylate aminotransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K14272  GGAT; glutamate--glyoxylate aminotransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.2  alanine transaminase
     K14272  GGAT; glutamate--glyoxylate aminotransferase
    2.6.1.4  glycine transaminase
     K14272  GGAT; glutamate--glyoxylate aminotransferase
    2.6.1.44  alanine---glyoxylate transaminase
     K14272  GGAT; glutamate--glyoxylate aminotransferase
Amino acid related enzymes [BR:ko01007]
 Aminotransferase (transaminase)
  Class I
   K14272  GGAT; glutamate--glyoxylate aminotransferase
BRITE hierarchy
Other DBs
RN: R00258 R00369 R00372
GO: 0047958 0004021 0008453
Genes
ATH: AT1G23310(GGT1) AT1G70580(AOAT2)
ALY: ARALYDRAFT_472589(GGT1) ARALYDRAFT_894873(AOAT2)
CRB: 17895448 17897757
CSAT: 104701699 104712607 104741047 104750897 104756699 104776459
EUS: EUTSA_v10007514mg EUTSA_v10018474mg
BRP: 103829276 103831592 103835672 103840779
BNA: 106356016 106358129 106390498 106406022 106415204 106434229 106440992 111207231
BOE: 106295814 106296220 106312468
RSZ: 108808579 108822099 108822100 108825821
THJ: 104822983
CPAP: 110817151
CIT: 102611899
TCC: 18609536
GRA: 105794627
GHI: 107909695
GAB: 108473496
EGR: 104414150
GMX: 100127414(ALAAT2) 100787173
VRA: 106777621
VAR: 108329166
VUN: 114173720
CCAJ: 109800924
CAM: 101508288
LJA: Lj2g3v1415440.1(Lj2g3v1415440.1) Lj2g3v1415440.2(Lj2g3v1415440.2) Lj2g3v1415440.3(Lj2g3v1415440.3)
ADU: 107488817
AIP: 107643316
FVE: 101304831
RCN: 112197874
PPER: 18788891
PMUM: 103321858
PAVI: 110760503
PXB: 103949832
ZJU: 107428611
RCU: 8273496
JCU: 105644652
QSU: 112010088
VVI: 100261274
INI: 109172057
HAN: 110871636
LSV: 111882299
CCAV: 112524428
BVG: 104897276
SOE: 110799230
OSA: 4342210
DOSA: Os07t0108300-01(Os07g0108300)
OBR: 102712276
BDI: 100844005
ATS: 109734653(LOC109734653)
SBI: 110432565
SITA: 101767913
PDA: 103707141
DCT: 110110983
PEQ: 110023535
AOF: 109833434
ATR: 18430615
CRE: CHLREDRAFT_206184(AAT1)
APRO: F751_3918
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3933486
  Authors
Takada Y, Noguchi T
  Title
Characteristics of alanine: glyoxylate aminotransferase from Saccharomyces cerevisiae, a regulatory enzyme in the glyoxylate pathway of glycine and serine biosynthesis from tricarboxylic acid-cycle intermediates.
  Journal
Biochem J 231:157-63 (1985)
DOI:10.1042/bj2310157
Reference
  Authors
Foyer CH, Bloom AJ, Queval G, Noctor G
  Title
Photorespiratory metabolism: genes, mutants, energetics, and redox signaling.
  Journal
Annu Rev Plant Biol 60:455-84 (2009)
DOI:10.1146/annurev.arplant.043008.091948
Reference
  Authors
Liepman AH, Olsen LJ
  Title
Alanine aminotransferase homologs catalyze the glutamate:glyoxylate aminotransferase reaction in peroxisomes of Arabidopsis.
  Journal
Plant Physiol 131:215-27 (2003)
DOI:10.1104/pp.011460
  Sequence

KEGG   ENZYME: 2.6.1.4Help
Entry
EC 2.6.1.4                  Enzyme                                 

Name
glycine transaminase;
glutamic-glyoxylic transaminase;
glycine aminotransferase;
glyoxylate-glutamic transaminase;
L-glutamate:glyoxylate aminotransferase;
glyoxylate-glutamate aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
glycine:2-oxoglutarate aminotransferase
Reaction(IUBMB)
glycine + 2-oxoglutarate = glyoxylate + L-glutamate [RN:R00372]
Reaction(KEGG)
Substrate
glycine [CPD:C00037];
2-oxoglutarate [CPD:C00026]
Product
glyoxylate [CPD:C00048];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein.
History
EC 2.6.1.4 created 1961, modified 1982
Pathway
ec00260  Glycine, serine and threonine metabolism
ec00630  Glyoxylate and dicarboxylate metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01130  Biosynthesis of antibiotics
Orthology
K14272  glutamate--glyoxylate aminotransferase
Genes
ATH: AT1G23310(GGT1) AT1G70580(AOAT2)
ALY: ARALYDRAFT_472589(GGT1) ARALYDRAFT_894873(AOAT2)
CRB: 17895448 17897757
CSAT: 104701699 104712607 104741047 104750897 104756699 104776459
EUS: EUTSA_v10007514mg EUTSA_v10018474mg
BRP: 103829276 103831592 103835672 103840779
BNA: 106356016 106358129 106390498 106406022 106415204 106434229 106440992 111207231
BOE: 106295814 106296220 106312468
RSZ: 108808579 108822099 108822100 108825821
THJ: 104822983
CPAP: 110817151
CIT: 102611899
TCC: 18609536
GRA: 105794627
GHI: 107909695
GAB: 108473496
EGR: 104414150
GMX: 100127414(ALAAT2) 100787173
VRA: 106777621
VAR: 108329166
VUN: 114173720
CCAJ: 109800924
CAM: 101508288
LJA: Lj2g3v1415440.1(Lj2g3v1415440.1) Lj2g3v1415440.2(Lj2g3v1415440.2) Lj2g3v1415440.3(Lj2g3v1415440.3)
ADU: 107488817
AIP: 107643316
FVE: 101304831
RCN: 112197874
PPER: 18788891
PMUM: 103321858
PAVI: 110760503
PXB: 103949832
ZJU: 107428611
RCU: 8273496
JCU: 105644652
QSU: 112010088
VVI: 100261274
INI: 109172057
HAN: 110871636
LSV: 111882299
CCAV: 112524428
BVG: 104897276
SOE: 110799230
OSA: 4342210
DOSA: Os07t0108300-01(Os07g0108300)
OBR: 102712276
BDI: 100844005
ATS: 109734653(LOC109734653)
SBI: 110432565
SITA: 101767913
PDA: 103707141
DCT: 110110983
PEQ: 110023535
AOF: 109833434
ATR: 18430615
CRE: CHLREDRAFT_206184(AAT1)
APRO: F751_3918
 » show all
Taxonomy
Reference
1  [PMID:14169146]
  Authors
NAKADA HI.
  Title
GLUTAMIC-GLYCINE TRANSAMINASE FROM RAT LIVER.
  Journal
J Biol Chem 239:468-71 (1964)
Reference
2
  Authors
Thompson, J.S. and Richardson, K.E.
  Title
Isolation and chracterization of a glutamate-glycine transaminase from human liver.
  Journal
Arch Biochem Biophys 117:599-603 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.4
IUBMB Enzyme Nomenclature: 2.6.1.4
ExPASy - ENZYME nomenclature database: 2.6.1.4
BRENDA, the Enzyme Database: 2.6.1.4
CAS: 9032-99-9

KEGG   REACTION: R00372Help
Entry
R00372                      Reaction                               

Name
Glycine:2-oxoglutarate aminotransferase
Definition
Glycine + 2-Oxoglutarate <=> Glyoxylate + L-Glutamate
Equation
Reaction class
RC00006  C00025_C00026
RC00018  C00037_C00048
Enzyme
2.6.1.4         2.6.1.44
Pathway
rn00260  Glycine, serine and threonine metabolism
rn00630  Glyoxylate and dicarboxylate metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01130  Biosynthesis of antibiotics
rn01200  Carbon metabolism
Module
M00532  Photorespiration
Orthology
K00827  alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase [EC:2.6.1.44 2.6.1.40]
K00830  alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
K14272  glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44]
Other DBs
RHEA: 14092

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