KEGG   ORTHOLOGY: K14285
Entry
K14285                      KO                                     

Name
NXT1_2, P15
Definition
NTF2-related export protein 1/2
Pathway
ko03008  Ribosome biogenesis in eukaryotes
ko03013  RNA transport
ko03015  mRNA surveillance pathway
ko05164  Influenza A
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 RNA transport
    K14285  NXT1_2, P15; NTF2-related export protein 1/2
   03015 mRNA surveillance pathway
    K14285  NXT1_2, P15; NTF2-related export protein 1/2
   03008 Ribosome biogenesis in eukaryotes
    K14285  NXT1_2, P15; NTF2-related export protein 1/2
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    K14285  NXT1_2, P15; NTF2-related export protein 1/2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K14285  NXT1_2, P15; NTF2-related export protein 1/2
   03009 Ribosome biogenesis
    K14285  NXT1_2, P15; NTF2-related export protein 1/2
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Nuclear pore complex
     K14285  NXT1_2, P15; NTF2-related export protein 1/2
Ribosome biogenesis [BR:ko03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    K14285  NXT1_2, P15; NTF2-related export protein 1/2
Other DBs
TC: 1.I.1.1
Genes
HSA: 29107(NXT1) 55916(NXT2)
PTR: 458138(NXT1) 473728(NXT2) 749583
PPS: 100969952(NXT1) 100984700(NXT2)
GGO: 101135325(NXT2) 101143744(NXT1)
PON: 100439933(NXT1) 100451590(NXT2)
NLE: 100589259(NXT2) 100601139(NXT1)
MCC: 704593(NXT2) 711846(NXT1)
MCF: 101925148(NXT2) 102122866(NXT1)
CSAB: 103215397(NXT1) 103232476(NXT2)
RRO: 104666927(NXT1) 104674382(NXT2)
RBB: 108520665(NXT1)
CJC: 100405107(NXT1) 100410924(NXT2)
SBQ: 101034347(NXT2) 101035352(NXT1)
MMU: 237082(Nxt2) 56488(Nxt1)
MCAL: 110286618(Nxt2) 110289496(Nxt1)
MPAH: 110313965(Nxt2) 110318880(Nxt1) 110335097
RNO: 296219(Nxt1) 315352(Nxt2)
MUN: 110541827 110560599(Nxt1)
CGE: 100761079 100763994(Nxt1)
NGI: 103737360(Nxt1) 103750025(Nxt2)
HGL: 101701680(Nxt1) 101718176(Nxt2) 101723716
CCAN: 109697970(Nxt1) 109698642(Nxt2)
OCU: 100339936(NXT2) 100351903(NXT1)
TUP: 102475069(NXT2) 102487518(NXT1)
CFA: 477132(NXT1) 612945(NXT2)
VVP: 112922701(NXT1) 112932045(NXT2)
AML: 100467867(NXT1) 100469359(NXT2)
UMR: 103677857(NXT1) 103679745(NXT2)
UAH: 113241236(NXT2) 113246769(NXT1)
ORO: 101371188(NXT2) 101383968(NXT1)
FCA: 101085619(NXT1) 101090496(NXT2)
PTG: 102950208(NXT2) 102962503(NXT1)
PPAD: 109253664(NXT2) 109274648(NXT1)
AJU: 106973155(NXT2) 106988195(NXT1)
BTA: 513043(NXT2) 520351(NXT1)
BOM: 102270915(NXT1) 102277343(NXT2)
BIU: 109555445(NXT2) 109568054(NXT1)
BBUB: 102402331(NXT2) 102407454(NXT1)
CHX: 102172640(NXT1) 102180832(NXT2)
SSC: 100514739(NXT1) 100521422(NXT2)
CFR: 102512919(NXT2) 102513088(NXT1)
CDK: 105093186(NXT2) 105106281(NXT1)
BACU: 102998580(NXT1) 103001168 103009015(NXT2)
LVE: 103069206(NXT2) 103086178(NXT1)
OOR: 101276877(NXT2) 101285083(NXT1)
DLE: 111165779(NXT2) 111185042(NXT1)
ECB: 100059798(NXT2) 102149448(NXT1)
EPZ: 103543935(NXT2)
EAI: 106839710(NXT2) 106841798(NXT1)
MYB: 102240474(NXT1) 102240824(NXT2)
MYD: 102759263(NXT1) 102772135(NXT2)
MNA: 107526021(NXT2) 107536323(NXT1)
HAI: 109376728(NXT2) 109377530(NXT1)
DRO: 112296892(NXT2) 112303956(NXT1)
PALE: 102879117 102897103(NXT1)
RAY: 107498637(NXT1) 107519301(NXT2)
MJV: 108384615(NXT2) 108406928(NXT1)
LAV: 100661632(NXT1) 100670537(NXT2)
PCW: 110194770(NXT2)
OAA: 100077395(NXT2)
GGA: 422346(NXT2)
MGP: 100540547(NXT2)
CJO: 107312774(NXT2)
NMEL: 110403015(NXT2)
APLA: 101799293(NXT2)
ACYG: 106038591(NXT2)
TGU: 100232267(NXT2)
LSR: 110480118(NXT2)
SCAN: 103816374(NXT2)
GFR: 102040999(NXT2)
FAB: 101820217(NXT2)
PHI: 102103755(NXT2)
PMAJ: 107203954(NXT2)
CCAE: 111928700(NXT2)
CCW: 104694455(NXT2)
ETL: 114059694(NXT2)
FPG: 101914758(NXT2)
FCH: 102050274(NXT2)
CLV: 102086248(NXT2)
EGZ: 104133276(NXT2)
NNI: 104023319(NXT2)
ACUN: 113479926(NXT2)
PADL: 103920155(NXT2)
AAM: 106482660(NXT2)
ASN: 102379715(NXT2)
AMJ: 102577210(NXT2)
PSS: 102457586(NXT2)
CMY: 102943050(NXT2)
CPIC: 101950871(NXT2)
ACS: 100564733(nxt2)
PVT: 110074325(NXT2)
PBI: 103052302(NXT2)
PMUR: 107287162 107287191(NXT2)
TSR: 106548518(NXT2)
PMUA: 114589122(NXT2)
GJA: 107114013(NXT2)
XLA: 379677(nxt2.L)
XTR: 100145163(nxt2)
NPR: 108799504
DRE: 751738(nxt2)
IPU: 108268938(nxt2)
PHYP: 113528933(nxt2)
AMEX: 103035937(nxt2)
EEE: 113582031(nxt2)
TRU: 101076590(nxt2)
LCO: 104922445(nxt2)
NCC: 104956337(nxt2)
MZE: 101471323
ONL: 100703071(nxt2)
OLA: 101172743(nxt2)
XMA: 102237466(nxt2)
XCO: 114139669(nxt2)
CVG: 107089740(nxt2)
NFU: 107384736(nxt2)
KMR: 108237962(nxt2)
ALIM: 106512121
AOCE: 111583180(nxt2)
CSEM: 103391379(nxt2)
POV: 109647530
LCF: 108882777(nxt2)
SDU: 111226569(nxt2)
HCQ: 109524247(nxt2)
BPEC: 110158127(nxt2)
SASA: 106604300(NXT2) 106612158(NXT2)
OTW: 112236578
ELS: 105024405(nxt2)
SFM: 108925409(nxt2)
PKI: 111853544(nxt2)
LCM: 102366181(NXT2)
CMK: 103178867(nxt2)
RTP: 109931648
CIN: 100184548
SPU: 764903
APLC: 110988649
SKO: 100368921
DME: Dmel_CG12752(Nxt1)
DER: 6548386
DSE: 6615774
DSI: Dsimw501_GD25012(Dsim_GD25012)
DYA: Dyak_GE11531(Dyak_Nxt1)
DAN: 6495309
DSR: 110180997
DPE: 6590673
DWI: 6652230
DAZ: 108618608
DNV: 108657316
DHE: 111594421
DVI: 6633679
MDE: 101898480
LCQ: 111685318
AALB: 109402269
AME: 413378
BIM: 100741620
BTER: 100648665
CCAL: 108623752
OBB: 114872580
SOC: 105200307
MPHA: 105833750
AEC: 105145641
ACEP: 105627923
PBAR: 105428653
HST: 105185710
DQU: 106749324
CFO: 105248026
LHU: 105670025
OBO: 105284097
PCF: 106789120
NVI: 100116332
CSOL: 105365889
MDL: 103578896
TCA: 657794
DPA: 109533075
NVL: 108563768
BMOR: 100101167
BMAN: 114245808
PMAC: 106721554
PRAP: 110997474
TNL: 113498689
PXY: 105382361
BTAB: 109033238
CLEC: 106665215
ZNE: 110837944
FCD: 110842843
PVM: 113805246
DPTE: 113790777
CSCU: 111642226
PTEP: 107441431
CEL: CELE_Y71F9AM.5(nxt-1)
CBR: CBG04218(Cbr-nxt-1)
BMY: Bm1_48170
PCAN: 112559864
MYI: 110455521
LAK: 106181279
NVE: 5521897
EPA: 110241929
ADF: 107348221
AMIL: 114955679
PDAM: 113668562
SPIS: 111337649
DGT: 114527626
HMG: 100214426
NCR: NCU03631
NTE: NEUTE1DRAFT98421(NEUTE1DRAFT_98421)
MGR: MGG_06948
SSCK: SPSK_05573
MAJ: MAA_06144
CMT: CCM_07912
MBE: MBM_07821
ANI: AN3864.2
ANG: ANI_1_468184(An04g02240)
SPO: SPAPB1A10.03(nxt1)
CNE: CNC00650
CNB: CNBC6590
ABP: AGABI1DRAFT67196(AGABI1DRAFT_67196)
ABV: AGABI2DRAFT147534(AGABI2DRAFT_147534)
MGL: MGL_0759
MRT: MRET_0059
DFA: DFA_08649
EHI: EHI_044880(3.t00008)
 » show all
Reference
  Authors
Levesque L, Guzik B, Guan T, Coyle J, Black BE, Rekosh D, Hammarskjold ML, Paschal BM
  Title
RNA export mediated by tap involves NXT1-dependent interactions with the nuclear pore complex.
  Journal
J Biol Chem 276:44953-62 (2001)
DOI:10.1074/jbc.M106558200
  Sequence
[mmu:56488]
Reference
  Authors
Herold A, Suyama M, Rodrigues JP, Braun IC, Kutay U, Carmo-Fonseca M, Bork P, Izaurralde E
  Title
TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.
  Journal
Mol Cell Biol 20:8996-9008 (2000)
DOI:10.1128/MCB.20.23.8996-9008.2000
  Sequence
[hsa:29107] [dme:Dmel_CG12752]
Reference
  Authors
Guzik BW, Levesque L, Prasad S, Bor YC, Black BE, Paschal BM, Rekosh D, Hammarskjold ML
  Title
NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells.
  Journal
Mol Cell Biol 21:2545-54 (2001)
DOI:10.1128/MCB.21.7.2545-2554.2001
  Sequence
[hsa:29107]

KEGG   ORTHOLOGY: K14543
Entry
K14543                      KO                                     

Name
MTR2
Definition
mRNA transport regulator MTR2
Pathway
ko03008  Ribosome biogenesis in eukaryotes
ko03013  RNA transport
ko03015  mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 RNA transport
    K14543  MTR2; mRNA transport regulator MTR2
   03015 mRNA surveillance pathway
    K14543  MTR2; mRNA transport regulator MTR2
   03008 Ribosome biogenesis in eukaryotes
    K14543  MTR2; mRNA transport regulator MTR2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K14543  MTR2; mRNA transport regulator MTR2
   03009 Ribosome biogenesis
    K14543  MTR2; mRNA transport regulator MTR2
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Nuclear pore complex
     K14543  MTR2; mRNA transport regulator MTR2
Ribosome biogenesis [BR:ko03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    K14543  MTR2; mRNA transport regulator MTR2
Other DBs
TC: 1.I.1.1
Genes
SCE: YKL186C(MTR2)
AGO: AGOS_AER089W
ERC: Ecym_3235
KLA: KLLA0_B02629g
KMX: KLMA_40530(MTR2)
LTH: KLTH0D15158g
VPO: Kpol_1001p29
ZRO: ZYRO0B13156g
CGR: CAGL0D00440g
NCS: NCAS_0A02660(NCAS0A02660)
NDI: NDAI_0D04590(NDAI0D04590)
TPF: TPHA_0B00650(TPHA0B00650)
TBL: TBLA_0I03130(TBLA0I03130)
TDL: TDEL_0E00860(TDEL0E00860)
KAF: KAFR_0G03390(KAFR0G03390)
CAL: CAALFM_C210640CA(MTR2)
 » show all
Reference
  Authors
Yao W, Roser D, Kohler A, Bradatsch B, Bassler J, Hurt E
  Title
Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2.
  Journal
Mol Cell 26:51-62 (2007)
DOI:10.1016/j.molcel.2007.02.018
  Sequence
[sce:YKL186C]

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