ORTHOLOGY: K14298 Help
Entry
Symbol
RAE1, GLE2
Name
Pathway
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09120 Genetic Information Processing
09122 Translation
03013 Nucleocytoplasmic transport
K14298 RAE1, GLE2; mRNA export factor
09160 Human Diseases
09172 Infectious disease: viral
05164 Influenza A
K14298 RAE1, GLE2; mRNA export factor
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
K14298 RAE1, GLE2; mRNA export factor
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis
K14298 RAE1, GLE2; mRNA export factor
03036 Chromosome and associated proteins
K14298 RAE1, GLE2; mRNA export factor
Messenger RNA biogenesis [BR:ko03019 ]
Eukaryotic type
mRNA surveillance and transport factors
Transport factors
Nuclear pore complex
K14298 RAE1, GLE2; mRNA export factor
Chromosome and associated proteins [BR:ko03036 ]
Eukaryotic type
Centrosome formation proteins
Spindle formation proteins
K14298 RAE1, GLE2; mRNA export factor
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Taxonomy UniProt
Reference
Authors
Pritchard CE, Fornerod M, Kasper LH, van Deursen JM
Title
RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains.
Journal
Sequence
Reference
Authors
Murphy R, Watkins JL, Wente SR
Title
GLE2, a Saccharomyces cerevisiae homologue of the Schizosaccharomyces pombe export factor RAE1, is required for nuclear pore complex structure and function.
Journal
Sequence
Reference
Authors
Bharathi A, Ghosh A, Whalen WA, Yoon JH, Pu R, Dasso M, Dhar R
Title
The human RAE1 gene is a functional homologue of Schizosaccharomyces pombe rae1 gene involved in nuclear export of Poly(A)+ RNA.
Journal
Sequence