KEGG   ORTHOLOGY: K14333
Entry
K14333                      KO                                     

Name
DHBD
Definition
2,3-dihydroxybenzoate decarboxylase [EC:4.1.1.46]
Pathway
ko00362  Benzoate degradation
ko00627  Aminobenzoate degradation
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K14333  DHBD; 2,3-dihydroxybenzoate decarboxylase
   00627 Aminobenzoate degradation
    K14333  DHBD; 2,3-dihydroxybenzoate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.46  o-pyrocatechuate decarboxylase
     K14333  DHBD; 2,3-dihydroxybenzoate decarboxylase
Other DBs
RN: R00821
COG: COG2159
GO: 0050150
Genes
QSU: 112021786
PAN: PODANSg3434
TTT: THITE_2141821
MTM: MYCTH_2299911
CTHR: CTHT_0064560
MGR: MGG_03793
TMN: UCRPA7_5617 UCRPA7_8825
SSCK: SPSK_05410
FGR: FGSG_09061
FPU: FPSE_07344
CMT: CCM_08209
ANI: AN6723.2
ANG: ANI_1_1020164(An18g00870) ANI_1_250064(An07g02050) ANI_1_2560024(An02g05560)
TASA: A1Q1_00374
ABP: AGABI1DRAFT108672(AGABI1DRAFT_108672)
ABV: AGABI2DRAFT210050(AGABI2DRAFT_210050)
EBI: EbC_26040
REH: H16_B0810(h16_B0810)
PSPU: NA29_13040
CABA: SBC2_53560(ligJ_1)
BPE: BP0578
BPC: BPTD_0587
BPER: BN118_3489
BPET: B1917_3476
BPEU: Q425_35710
BPAR: BN117_0266
BPA: BPP0268
BBR: BB0271
BAV: BAV2745
AFQ: AFA_15145(picC)
RPB: RPB_3105
XAU: Xaut_2054
SNO: Snov_1130
MHAD: B586_01905
MVQ: MYVA_5778
SMAL: SMALA_8227
 » show all
Reference
PMID:8620029
  Authors
Santha R, Rao NA, Vaidyanathan CS
  Title
Identification of the active-site peptide of 2,3-dihydroxybenzoic acid decarboxylase from Aspergillus oryzae.
  Journal
Biochim Biophys Acta 1293:191-200 (1996)
DOI:10.1016/0167-4838(95)00242-1
  Sequence

KEGG   ENZYME: 4.1.1.46
Entry
EC 4.1.1.46                 Enzyme                                 

Name
o-pyrocatechuate decarboxylase;
2,3-dihydroxybenzoate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
2,3-dihydroxybenzoate carboxy-lyase (catechol-forming)
Reaction(IUBMB)
2,3-dihydroxybenzoate = catechol + CO2 [RN:R00821]
Reaction(KEGG)
R00821
Substrate
2,3-dihydroxybenzoate [CPD:C00196]
Product
catechol [CPD:C00090];
CO2 [CPD:C00011]
History
EC 4.1.1.46 created 1972
Pathway
ec00362  Benzoate degradation
ec00627  Aminobenzoate degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K14333  2,3-dihydroxybenzoate decarboxylase
Genes
QSU: 112021786
PAN: PODANSg3434
TTT: THITE_2141821
MTM: MYCTH_2299911
CTHR: CTHT_0064560
MGR: MGG_03793
TMN: UCRPA7_5617 UCRPA7_8825
SSCK: SPSK_05410
FGR: FGSG_09061
FPU: FPSE_07344
CMT: CCM_08209
ANI: AN6723.2
ANG: ANI_1_1020164(An18g00870) ANI_1_250064(An07g02050) ANI_1_2560024(An02g05560)
TASA: A1Q1_00374
ABP: AGABI1DRAFT108672(AGABI1DRAFT_108672)
ABV: AGABI2DRAFT210050(AGABI2DRAFT_210050)
EBI: EbC_26040
REH: H16_B0810(h16_B0810)
PSPU: NA29_13040
CABA: SBC2_53560(ligJ_1)
BPE: BP0578
BPC: BPTD_0587
BPER: BN118_3489
BPET: B1917_3476
BPEU: Q425_35710
BPAR: BN117_0266
BPA: BPP0268
BBR: BB0271
BAV: BAV2745
AFQ: AFA_15145(picC)
RPB: RPB_3105
XAU: Xaut_2054
SNO: Snov_1130
MHAD: B586_01905
MVQ: MYVA_5778
SMAL: SMALA_8227
 » show all
Reference
1  [PMID:6066253]
  Authors
Rao PV, Moore K, Towers GH.
  Title
O-pyrocatechiuc acid carboxy-lyase from Aspergillus niger.
  Journal
Arch Biochem Biophys 122:466-73 (1967)
DOI:10.1016/0003-9861(67)90220-2
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.46
IUBMB Enzyme Nomenclature: 4.1.1.46
ExPASy - ENZYME nomenclature database: 4.1.1.46
UM-BBD (Biocatalysis/Biodegradation Database): 4.1.1.46
BRENDA, the Enzyme Database: 4.1.1.46
CAS: 37289-48-8

KEGG   REACTION: R00821
Entry
R00821                      Reaction                               

Name
2,3-dihydroxybenzoate carboxy-lyase
Definition
2,3-Dihydroxybenzoate <=> Catechol + CO2
Equation
Reaction class
RC00390  C00090_C00196
Enzyme
Pathway
rn00362  Benzoate degradation
rn00627  Aminobenzoate degradation
rn01120  Microbial metabolism in diverse environments
Orthology
K14333  2,3-dihydroxybenzoate decarboxylase [EC:4.1.1.46]
Other DBs
RHEA: 21495

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