KEGG   ORTHOLOGY: K14449
Entry
K14449                      KO                                     
Symbol
mch, mcd
Name
2-methylfumaryl-CoA hydratase [EC:4.2.1.148]
Pathway
map00630  Glyoxylate and dicarboxylate metabolism
map00660  C5-Branched dibasic acid metabolism
map00720  Other carbon fixation pathways
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
Module
M00373  Ethylmalonyl pathway
M00376  3-Hydroxypropionate bi-cycle
M00740  Methylaspartate cycle
Reaction
R05076  (2R,3S)-2-methylmalyl-CoA hydro-lyase (2-methylfumaryl-CoA-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K14449  mch, mcd; 2-methylfumaryl-CoA hydratase
   00660 C5-Branched dibasic acid metabolism
    K14449  mch, mcd; 2-methylfumaryl-CoA hydratase
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    K14449  mch, mcd; 2-methylfumaryl-CoA hydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.148  2-methylfumaryl-CoA hydratase
     K14449  mch, mcd; 2-methylfumaryl-CoA hydratase
Other DBs
COG: COG2030
GO: 0043881
Genes
PAGR: E2H98_04135
KAK: Kalk_01780
THT: E2K93_09440
THAP: FNC98_15555
TPSY: RGQ13_18675
TNN: RI845_01140
TFT: RI844_12645
THIP: N838_00820
PLEI: Q9312_08220
KKO: Kkor_1561
KGE: TQ33_0883
KSD: KS2013_924
KPD: CW740_07365
KAM: SR900_06895
CBLY: IPM89_03160
GPB: HDN1F_16000(maoC)
RPJ: N234_23790
REH: H16_B0354(h16_B0354)
CUH: BJN34_06615 BJN34_32795
REU: Reut_B4149
RME: Rmet_4428
COX: E0W60_35065
CUK: KB879_34860
AXY: AXYL_04959
MMB: Mmol_0752
MEH: M301_0690
MBAC: BN1209_0534
MEU: ACJ67_09150
GCA: Galf_0005
URU: DSM104443_01837(mch)
UPL: DSM104440_01704(mch)
APP: CAP2UW1_2498 CAP2UW1_2509
BEB: AEM42_12675
BEBA: BWI17_17565
PLA: Plav_1430
PMOB: HG718_14780
KMN: HW532_11385
PECT: BN1012_Phect1282
RBS: RHODOSMS8_02865(mch)
HOE: IMCC20628_00131
BVV: BHK69_04050
BVES: QO058_14900
BOP: AXW83_18685
BOS: BSY19_19
BOI: BLM15_22575
BOF: FQV39_20495
BOW: NWE53_17950
BOSE: RMR04_31455
XAU: Xaut_1970
XDI: EZH22_04685
AZC: AZC_3739(maoC)
MEA: Mex_1p4153(meaC)
MDI: METDI4744(mcd)
MEX: Mext_3781
MCH: Mchl_4075
MPO: Mpop_4037
MZA: B2G69_00715
MRD: Mrad2831_4465
MET: M446_3940
MNO: Mnod_3627
MOR: MOC_5123
META: Y590_18780
MAQU: Maq22A_c24130(meaC)
MPHY: MCBMB27_03974
MEE: DA075_14875
METD: C0214_21035
METX: A3862_09080
METS: DK389_24235
METI: DK427_20415
MMES: MMSR116_09355
MTEA: DK419_24615
MIND: mvi_45470
MOG: MMB17_08775
MTAD: M6G65_23985
RHJ: HZY79_05500
CHEL: AL346_08910
CDQ: BOQ54_02010
HDN: Hden_3241
HDT: HYPDE_39543
HMC: HYPMC_4595(meaC)
HNI: W911_01750
RVA: Rvan_0096
RLAC: QMO75_06800
FIL: BN1229_v1_1105
FIY: BN1229_v1_1106
RHZ: RHPLAN_04430
MCG: GL4_0095
METG: HT051_02330
BVR: BVIR_2665
BLAG: BLTE_30930
MSC: BN69_0351
MBRY: B1812_00605
MROS: EHO51_06320
MHEY: H2LOC_003165
MPAR: F7D14_17160
MIWA: SS37A_18910(mch_2)
MESZ: LNB28_01475
MTW: CQW49_03910
MECQ: MSC49_27390
CMET: K6K41_13785
PLEO: OHA_1_03194(meaC)
HDI: HDIA_0200
PSIN: CAK95_07805
NOH: G5V57_10435
RBM: TEF_04290
BRN: D1F64_22685
PSF: PSE_4924
PPHR: APZ00_07775
LAP: ACP90_02630
LABR: CHH27_17905
LABP: FJ695_06270
LABT: FIU93_08255
LAGG: B0E33_14110
RPOP: K1718_03370
SIW: GH266_13030
PHR: C6569_01280
PSTG: E8M01_18925
PAQT: E8L99_10920
CCR: CC_3656
CCS: CCNA_03771
CAK: Caul_5003
CSE: Cseg_4148
CHQ: AQ619_17495
CMB: CSW64_19910
CFH: C1707_05910
CAUF: CSW63_22650
TSV: DSM104635_00255
SIL: SPO0355
SIT: TM1040_3523
RUA: D1823_12155
RUT: FIU92_01335
RCON: K3740_01485
RUY: NOR97_01025
JAN: Jann_0813
RDE: RD1_1623
RLI: RLO149_c030850
RPON: G3256_15350
RFU: ROLI_007960(mch)
DSH: Dshi_2871
PGA: PGA1_c03710
PGL: PGA2_c03270
PGD: Gal_03131
PHP: PhaeoP97_02985
PPIC: PhaeoP14_00288
PHQ: D1820_14710
OAT: OAN307_c41490
OAR: OA238_c04280
OTM: OSB_04790
OCT: FTO60_03000
LMD: METH_03330
LEJ: ETW24_04135
LAQU: R2C4_13620
LEV: ETW23_16065
LCAE: K3721_03450
RED: roselon_01724
CID: P73_3865
CMAR: IMCC12053_3017
CEH: CEW89_10085
CBAK: DA792_14100
MALG: MALG_02742
CON: TQ29_02455
YPAC: CEW88_11150
YAN: AYJ57_04535
TPRO: Ga0080559_TMP1133
PABY: Ga0080574_TMP3145
SUAM: BOO69_13695
SULZ: C1J03_18205
SULI: C1J05_18095
SULD: B5M07_04965
SPOT: G6548_04130
SMED: JNX03_18035
SINL: DSM14862_02489(mch)
SFAV: PL335_11860
SUAL: KDD17_02125
SDUB: R1T39_14790
SPSE: SULPSESMR1_00397(mch)
TOM: BWR18_01040
RMM: ROSMUCSMR3_02502(mch)
ROK: RAK1035_0680
RID: RIdsm_04535
ROM: EI983_02915
ROH: FIU89_19165
RPEL: N7U68_08415
AHT: ANTHELSMS3_02130(mch)
SAGU: CDO87_04375
THAA: CFI11_04370
OCD: FHY55_05870
ROT: FIV09_01395
RMH: LVO79_01070
MALU: KU6B_41810(mch)
TGL: HFZ77_08400
TMD: KUV46_05985
HAT: RC74_09380
PALX: GQA70_04805
LSAL: KBK07_01430
LALG: LentiSH36_00612
TRY: QF118_18670
MARU: FIU81_04130
RMAI: MACH21_05310(mch)
RSP: RSP_0973
RSH: Rsph17029_2633
RSQ: Rsph17025_0085
RSK: RSKD131_2365
CAZT: LV780_00430
RCP: RCAP_rcc00730(maoC)
RHP: LPB142_03430
RBL: B6K69_07610
FYT: QF092_08900
PDE: Pden_0566
PAMI: JCM7686_2571
PYE: A6J80_13315
PCON: B0A89_09560
PZH: CX676_05520
PARO: CUV01_17705
PAMN: JCM7685_2542
PMUT: DPM13_11795
PARR: EOJ32_08555
PAAK: FIU66_10015
PKD: F8A10_02180
PPAN: ESD82_12335
PLIA: E4191_08460
PSAN: HGN31_04080
PMAU: CP157_01936(mch)
PMEH: JWJ88_02010
PSEW: JHW44_08025
PSAP: JHX88_13525
PFIS: JHX87_05205
PAEX: JHW48_10970
PSTL: JHW45_07360
PALP: JHW40_16585
PVER: E3U25_22195
PFEO: E3U26_10455
PTP: RCA23_c14030
RSU: NHU_00727(maoC)
RHM: B5V46_04490
RHC: RGUI_0619
RMB: K529_020755
TSCO: R1T40_12720
DAA: AKL17_3640
DON: BSK21_11425
RBZ: B9057_02190
THW: BMG03_06685
TEC: AKL02_005540
LVS: LOKVESSMR4R_02800(mch)
GEH: HYN69_13100
GFU: KM031_13950
TAW: EI545_06960
SALO: EF888_18555
SEDI: EBB79_02265
PPSO: QPJ95_04685
BOO: E2K80_01980
PSEB: EOK75_09385
PPRU: FDP22_03655
PAED: G5B38_15505
MON: G8E03_14620
PAMO: BAR1_14380
POZ: I0K15_13755
PALW: PSAL_019000(mch)
PSHQ: F3W81_20290
PGV: SL003B_0349
CACT: HZ995_03645
THAS: C6Y53_10255
HDH: G5B40_16095
CMAG: CBW24_13070
GCE: KYE46_04220
GYJ: AADW23_01300
NSM: JO391_19980
ACRO: K3J57_02785
SINR: O5O51_12640
AALK: LGT41_0002060
AMYL: QBD29_06855
AMAQ: GO499_14335
RHOC: QTA57_01890
PBAE: P8S53_11210
RBG: BG454_13670
BOSG: GKR98_08720
FAQ: G5B39_05130
RBX: I3V23_06865
HNE: HNE_3531
HBA: Hbal_0271
CBOT: ATE48_08620
HBC: AEM38_13390
RAP: RHOA_5786(mch)
SKT: IGS68_03940
SMUC: JL100_004090
SROE: JL101_003845
RRU: Rru_A1201
RRF: F11_06220
RPM: RSPPHO_01637
MGY: MGMSRv2__2222
MGRY: MSR1_22170
MAGX: XM1_1405
MAGN: WV31_15110
FER: FNB15_04090
DEX: HWD60_03945
DVN: HQ394_01630
HTQ: FRZ44_48910(mch)
HADH: FRZ61_47240(mch)
TXI: TH3_18445
THAC: CSC3H3_17630
TII: DY252_03095
THAI: IT893_17685
TLU: R1T41_05980
TTB: MACH01_34340
THGO: M9H61_15845
MAGQ: MGMAQ_3595
VSU: P3M64_11485
TMO: TMO_3272
ECOG: FIV45_00800
SNEA: NBZ79_01560
ABU: Abu_1926
ABT: ABED_1735
ABL: A7H1H_1860
ASK: EI285_07625
ATP: ATR_1699
ACIB: ACBT_0661
ACRE: ACRYA_0277
ALAN: ALANTH_1851
AFC: AFAEC_0403
ATHR: ATH_0463
ANT: Arnit_2997
AELL: AELL_2338
AAQI: AAQM_2072
ASUI: ASUIS_2143
ACLO: ACLO_2181
AVP: AVENP_2538
ADZ: ADFLV_2468
ARC: ABLL_2357
PACO: AACT_2435
APOC: APORC_0472
AROS: NJU99_11910
ALK: ALEK_2814
ALP: LPB137_11165
AHS: AHALO_1280
AMYT: AMYT_1371
AMAR: AMRN_1288
ACAA: ACAN_1329
AMOL: AMOL_1357
APAI: APAC_2032
HBV: ABIV_1149
HEBR: AEBR_1424
AANA: AANAER_1375
MZL: GKS04_00045
SCL: sce0588
SCU: SCE1572_04070
PAUU: E8A73_012220
MRM: A7982_10445
ARS: ADJ73_08750
JTE: ASJ30_03560
JLI: EXU32_11335
JME: EEW87_011215
JAY: H7A72_03565
JCR: O9K63_16225
AUS: IPK37_14060
NOI: FCL41_11755
NSN: EXE58_13390
NBE: Back2_07760(mch)
NARO: CFH99_08310
NPI: G7071_09440
NOQ: LN652_19075
NPC: KUV85_09000
NFC: KG111_12740
NRN: SHK17_05655
NBI: SHK19_06135
PSIM: KR76_08755
AER: AERYTH_05815
AEZ: C3E78_13730
AEB: C6I20_02560
AEF: GEV26_03685
ASEZ: H9L21_11640
ADB: NP095_11735
AWN: NQV15_13930
EKE: EK0264_18180
ATQ: GH723_14180
RRS: RoseRS_4172
RCA: Rcas_0913
CAU: Caur_0173
CHL: Chy400_0186
CAG: Cagg_1326
LIL: LA_2627
LIE: LIF_A2151
LIC: LIC_11359(maoC)
LIS: LIL_11480
LBJ: LBJ_1640(maoC)
LBL: LBL_1859(maoC)
LBI: LEPBI_I0786
LBF: LBF_0760(maoC)
LST: LSS_02729
LAJ: A0128_11715
LMAY: DPV73_12235
LKM: EFP84_03615
LWL: FHG68_12355
LKB: LPTSP3_g27670
LNO: MAL08_06760
LKR: FH602_12015
TPX: Turpa_2138
GGR: HKW67_06645
HALX: M0R89_18085
HAXY: NGM07_04615
SALI: L593_04665
HMA: rrnAC0688
HHI: HAH_1340
HHN: HISP_06860
HAB: SG26_14705
HTA: BVU17_06530
HALJ: G9465_08580
HSIN: KDQ40_06770
HMU: Hmuk_2983
HALZ: E5139_02190
HALL: LC1Hm_2320(mch3)
HAZP: GBQ70_02190
HRR: HZS55_19990
HPEL: HZS54_23490
HTU: Htur_1591
HSAL: JMJ58_00680
HAKZ: J0X25_14765
NMG: Nmag_3337(msh)
HXA: Halxa_3158
NAT: NJ7G_3290
NPE: Natpe_2591
NVR: FEJ81_11885
NPL: FGF80_10925
NAY: HYG81_14695
HALY: HYG82_17315
HJT: DVR14_02940
HLO: J0X27_02300
NGE: Natgr_3385
HRU: Halru_1549
SAWL: NGM29_08775
HALV: NGM15_00940
NOU: Natoc_1510
HLR: HALLA_10840
HLC: CHINAEXTREME16080
NAJ: B1756_12020
NAG: AArcMg_1646 AArcMg_4139
NAN: AArc1_1993 AArc1_5074
NARA: QQ977_05695(mch)
NBG: DV706_12985
NAS: GCU68_13730
HDA: BB347_04015
MSE: Msed_1216
MEMJ: MJ1HA_1378
MPRU: DFR88_00425
MTEN: GWK48_10815
MJN: MjAS7_2224
SAHS: HS7_11510
VDI: Vdis_0232
 » show all
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
  Sequence
[cau:Caur_0173] [rsp:RSP_0973]
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
  Sequence
[hma:rrnAC0688]

  All links  
Ontology (4)   
   KEGG BRITE (2)   
   GO (1)   
   COG (1)   
Pathway (15)   
   KEGG PATHWAY (12)   
   KEGG MODULE (3)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (3535)   
   KEGG GENES (451)   
   KEGG MGENES (2485)   
   RefGene (595)   
   OC (4)   
Literature (2)   
   PubMed (2)   
All databases (3559)   

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