KEGG   ORTHOLOGY: K14469Help
Entry
K14469                      KO                                     

Name
K14469
Definition
acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase [EC:1.3.1.84 4.2.1.116 6.2.1.36]
Pathway
ko00720  Carbon fixation pathways in prokaryotes
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00376  3-Hydroxypropionate bi-cycle
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Carbon fixation pathways in prokaryotes
    K14469  K14469; acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.84  acrylyl-CoA reductase (NADPH)
     K14469  K14469; acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.116  3-hydroxypropionyl-CoA dehydratase
     K14469  K14469; acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.36  3-hydroxypropionyl-CoA synthase
     K14469  K14469; acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase
BRITE hierarchy
Other DBs
RN: R00919 R03045 R09286
GO: 0043957 0043956 0043955
Genes
RRS: RoseRS_3202
RCA: Rcas_2930
CAU: Caur_0613
CHL: Chy400_0662
CAG: Cagg_3394
CTM: Cabther_B0610
CTS: Ctha_1050
TaxonomyKoalaUniProt
Reference
  Authors
Zarzycki J, Brecht V, Muller M, Fuchs G
  Title
Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus.
  Journal
Proc Natl Acad Sci U S A 106:21317-22 (2009)
DOI:10.1073/pnas.0908356106
Reference
  Authors
Alber BE, Fuchs G
  Title
Propionyl-coenzyme A synthase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO2 fixation.
  Journal
J Biol Chem 277:12137-43 (2002)
DOI:10.1074/jbc.M110802200
  Sequence

KEGG   ORTHOLOGY: K15020Help
Entry
K15020                      KO                                     

Name
K15020
Definition
acryloyl-coenzyme A reductase [EC:1.3.1.84]
Pathway
ko00720  Carbon fixation pathways in prokaryotes
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00375  Hydroxypropionate-hydroxybutylate cycle
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Carbon fixation pathways in prokaryotes
    K15020  K15020; acryloyl-coenzyme A reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.84  acrylyl-CoA reductase (NADPH)
     K15020  K15020; acryloyl-coenzyme A reductase
BRITE hierarchy
Other DBs
RN: R00919
COG: COG1064
GO: 0043958
Genes
MRM: A7982_09690
TAC: Ta0841
TVO: TVG0995648(TVG0995648)
PTO: PTO1151
FAC: FACI_IFERC01G0984
FAI: FAD_0007
CDIV: CPM_0774
STO: STK_04800
SSO: SSO0764(adh-2)
SOL: Ssol_1823
SSOA: SULA_1853
SSOL: SULB_1854
SSOF: SULC_1852
SAI: Saci_0911(adh)
SID: M164_1370
SII: LD85_1501
SIH: SiH_1323
SIR: SiRe_1239
SIC: SiL_1236
MSE: Msed_1426
MCN: Mcup_0809
AHO: Ahos_2283
PAI: PAE1921
PIS: Pisl_1770
PCL: Pcal_0882
PAS: Pars_2114
PYR: P186_0181
POG: Pogu_2773
TNE: Tneu_0785
CMA: Cmaq_1615
TUZ: TUZN_1795
TTN: TTX_1731(adhP)
VDI: Vdis_0393
VMO: VMUT_1233
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Teufel R, Kung JW, Kockelkorn D, Alber BE, Fuchs G
  Title
3-hydroxypropionyl-coenzyme A dehydratase and acryloyl-coenzyme A reductase, enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in the Sulfolobales.
  Journal
J Bacteriol 191:4572-81 (2009)
DOI:10.1128/JB.00068-09
  Sequence
[sto:STK_04800]
Reference
  Authors
Ramos-Vera WH, Weiss M, Strittmatter E, Kockelkorn D, Fuchs G
  Title
Identification of missing genes and enzymes for autotrophic carbon fixation in crenarchaeota.
  Journal
J Bacteriol 193:1201-11 (2011)
DOI:10.1128/JB.01156-10

KEGG   REACTION: R00919Help
Entry
R00919                      Reaction                               

Name
propanoyl-CoA:NADP+ 2-oxidoreductase;
acrylyl-CoA reductase (NADPH)
Definition
Propanoyl-CoA + NADP+ <=> Propenoyl-CoA + NADPH + H+
Equation
Reaction class
RC00001  C00005_C00006
RC00095  C00100_C00894
Enzyme
1.3.1.84        1.3.1.-
Pathway
rn00640  Propanoate metabolism
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00375  Hydroxypropionate-hydroxybutylate cycle
M00376  3-Hydroxypropionate bi-cycle
Orthology
K14469  acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase [EC:1.3.1.84 4.2.1.116 6.2.1.36]
K15020  acryloyl-coenzyme A reductase [EC:1.3.1.84]
K19745  acrylyl-CoA reductase (NADPH) [EC:1.3.1.-]

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