KEGG   ORTHOLOGY: K14630
Entry
K14630                      KO                                     

Name
actVA5
Definition
two-component flavin-dependent monooxygenase [EC:1.14.14.-]
Pathway
ko01057  Biosynthesis of type II polyketide products
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00779  Dihydrokalafungin biosynthesis, octaketide => dihydrokalafungin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K14630  actVA5; two-component flavin-dependent monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K14630  actVA5; two-component flavin-dependent monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.-  
     K14630  actVA5; two-component flavin-dependent monooxygenase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Oxygenase
   K14630  actVA5; two-component flavin-dependent monooxygenase
Other DBs
RN: R09313 R09314
Genes
SCO: SCO5080(actVA5)
SDV: BN159_2499
SLV: SLIV_12985
SVT: SVTN_18835
SGD: ELQ87_08030
SCYA: EJ357_29930
SRK: FGW37_16310
TFU: Tfu_1234
FRA: Francci3_4102
FRI: FraEuI1c_1309
CAI: Caci_6489
 » show all
Reference
  Authors
Valton J, Filisetti L, Fontecave M, Niviere V
  Title
A two-component flavin-dependent monooxygenase involved in actinorhodin biosynthesis in Streptomyces coelicolor.
  Journal
J Biol Chem 279:44362-9 (2004)
DOI:10.1074/jbc.M407722200
Reference
  Authors
Valton J, Fontecave M, Douki T, Kendrew SG, Niviere V
  Title
An aromatic hydroxylation reaction catalyzed by a two-component FMN-dependent Monooxygenase. The ActVA-ActVB system from Streptomyces coelicolor.
  Journal
J Biol Chem 281:27-35 (2006)
DOI:10.1074/jbc.M506146200
Reference
  Authors
Ellis HR
  Title
The FMN-dependent two-component monooxygenase systems.
  Journal
Arch Biochem Biophys 497:1-12 (2010)
DOI:10.1016/j.abb.2010.02.007

DBGET integrated database retrieval system