KEGG ORTHOLOGY: K14631

ORTHOLOGY: K14631

Entry

K14631                      KO

Symbol

actVB

Name

flavin reductase ActVB [EC:1.5.1.-]

Pathway

map01057

Biosynthesis of type II polyketide products

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00779

Dihydrokalafungin biosynthesis, octaketide => dihydrokalafungin

Reaction

R05705

FMNH2:NAD+ oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K14631  actVB; flavin reductase ActVB
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K14631  actVB; flavin reductase ActVB
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide tailoring proteins
  Others
   K14631  actVB; flavin reductase ActVB

Genes

BURT:

BTHE68_47210

BUO:	BRPE64_CCDS02020

CABK:

NK8_50370

BUE:	BRPE67_CCDS03520

CID:

P73_0185

PABY:

Ga0080574_TMP226

NOV:	TQ38_005245

CVA:

CVAR_0219

NNO:	NONO_c51280

NOZ:	DMB37_03455

NAD:	NCTC11293_02475(hsaB_3)

ROP:

ROP_46610

RAV:	AAT18_00630

RPSK:

JWS13_31200

RHOX:

RBB84_19630

RHZQ:

GO592_35460

SCO:	SCO5092(SCBAC28G1.18)

SVL:	Strvi_8777

SHY:

SHJG_7334

SHO:	SHJGH_7094

SRC:	M271_11995 M271_12030 M271_12130 M271_12185 M271_27745

SMAL:

SMALA_1304 SMALA_1311

SSOI:

I1A49_10060 I1A49_10095

SDV:	BN159_2429 BN159_6232

SLV:	SLIV_12925(actVB)

SCW:	TU94_00765

SPRI:

SPRI_0289 SPRI_7064

SRW:	TUE45_01562(snaC)

SLE:	sle_03080(sle_03080)

SGM:	GCM10017557_73680

SLS:	SLINC_8299

SPLU:

LK06_027530

STRD:

NI25_26845

SAUO:

BV401_10330 BV401_10365

SSIA:

A7J05_33160

SPUN:

BFF78_30195

SALF:

SMD44_00656(actVB)

SALJ:

SMD11_0681(actVB) SMD11_1393(actVB)

SLX:	SLAV_40520(snaC2)

SFK:

KY5_7707c

SCYA:

EJ357_29990

SAST:

CD934_07065

SKA:	CP970_00920 CP970_43535

SRK:	FGW37_16255

SFUG:

CNQ36_29940

SPLA:

CP981_11505 CP981_35180

SBRO:

GQF42_13985

SPEU:

CGZ69_08235

SANU:

K7396_07525

SLF:	JEQ17_32925

SDEC:

STUB:

SCIR:

STUD:

SANT:

QR300_24085 QR300_35275 QR300_35290

SCYN:

N8I84_07880

SOV:	QZH56_23735

SHAU:

K9S39_36135

SFP:	QUY26_37265

SINN:

ABB07_27365

SLUO:

PS467_32370 PS467_32405

STPB:

SRPA:

SCAJ:

SABD:

SCIT:

KNB:	ACF9IK_29140

STRH:

GXP74_39495

MRN:	K8F61_18715

SKE:	Sked_02120

SBIL:

SANBI_000206

NDK:	I601_2566(snaC)

THAO:

NI17_009020

TBI:

Tbis_2517

FRA:	Francci3_4133

FRE:	Franean1_3492

FRI:	FraEuI1c_4561

BSD:	BLASA_1412

AAB:	A4R43_29785

AROO:

NQK81_43485

ANW:	QP939_20785 QP939_20810

PBRO:

HOP40_33380

PPEL:

H6H00_19365

PSDS:

K1T35_37480

SSYI:

EKG83_16295 EKG83_30880

KBR:	Q4V65_06820

UME:	RM788_04780

SAQ:

Sare_0591

VER:	HUT12_14520

ASE:	ACPL_2178(ntaB) ACPL_6076

ACTS:

ACWT_2056 ACWT_5944

CCAZ:

COUCH_16040

CAI:

Caci_6495

AEY:	CDG81_21365

RXY:

Rxyl_1781

» show all

Reference

PMID:15297451

Authors

Valton J, Filisetti L, Fontecave M, Niviere V

Title

A two-component flavin-dependent monooxygenase involved in actinorhodin biosynthesis in Streptomyces coelicolor.

Journal

J Biol Chem 279:44362-9 (2004)
DOI:10.1074/jbc.M407722200

Reference

PMID:16267053

Authors

Valton J, Fontecave M, Douki T, Kendrew SG, Niviere V

Title

An aromatic hydroxylation reaction catalyzed by a two-component FMN-dependent Monooxygenase. The ActVA-ActVB system from Streptomyces coelicolor.

Journal

J Biol Chem 281:27-35 (2006)
DOI:10.1074/jbc.M506146200

Reference

PMID:20193654

Authors

Ellis HR

Title

The FMN-dependent two-component monooxygenase systems.

Journal

Arch Biochem Biophys 497:1-12 (2010)
DOI:10.1016/j.abb.2010.02.007

Reference

PMID:12417584

Authors

Filisetti L, Fontecave M, Niviere V

Title

Mechanism and substrate specificity of the flavin reductase ActVB from Streptomyces coelicolor.

Journal

J Biol Chem 278:296-303 (2003)
DOI:10.1074/jbc.M209689200

All links

Gene (3)   
   MGENES (1)   
   OC (2)   
All databases (3)   

Download RDF

DBGET integrated database retrieval system