KEGG   ORTHOLOGY: K14632
Entry
K14632                      KO                                     

Name
actVA6
Definition
C-6 monooxygenase
Pathway
ko01057  Biosynthesis of type II polyketide products
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00779  Dihydrokalafungin biosynthesis, octaketide => dihydrokalafungin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K14632  actVA6; C-6 monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K14632  actVA6; C-6 monooxygenase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Oxygenase
   K14632  actVA6; C-6 monooxygenase
Other DBs
RN: R06696
Genes
DUG: HH213_27030
RTM: G4H71_15880
SCO: SCO5081(actVA6)
SLV: SLIV_12980
SCYA: EJ357_29935
SRK: FGW37_16170
SRO: Sros_4752
AOI: AORI_4199
AJA: AJAP_17915
AORI: SD37_21520
CAI: Caci_6490
 » show all
Reference
PMID:9209048
  Authors
Kendrew SG, Hopwood DA, Marsh EN
  Title
Identification of a monooxygenase from Streptomyces coelicolor A3(2) involved in biosynthesis of actinorhodin: purification and characterization of the recombinant enzyme.
  Journal
J Bacteriol 179:4305-10 (1997)
DOI:10.1128/JB.179.13.4305-4310.1997
Reference
  Authors
Sciara G, Kendrew SG, Miele AE, Marsh NG, Federici L, Malatesta F, Schimperna G, Savino C, Vallone B
  Title
The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis.
  Journal
EMBO J 22:205-15 (2003)
DOI:10.1093/emboj/cdg031

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