KEGG   ORTHOLOGY: K14940
Entry
K14940                      KO                                     

Name
cofF
Definition
gamma-F420-2:alpha-L-glutamate ligase [EC:6.3.2.32]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K14940  cofF; gamma-F420-2:alpha-L-glutamate ligase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.32  coenzyme gamma-F420-2:alpha-L-glutamate ligase
     K14940  cofF; gamma-F420-2:alpha-L-glutamate ligase
Other DBs
RN: R09401
COG: COG0189
Genes
SON: SO_2200(rimK)
SAZ: Sama_1999
SBL: Sbal_1848
SBM: Shew185_1834
SBN: Sbal195_1882
SBP: Sbal223_2443
SBT: Sbal678_1921
SBS: Sbal117_1966
SBB: Sbal175_2505
SPC: Sputcn32_1744
SHP: Sput200_1771
SHE: Shewmr4_2195
SHM: Shewmr7_2272
SHN: Shewana3_2405
SHW: Sputw3181_2281
SHF: CEQ32_03360
SBJ: CF168_08980
SHEW: CKQ84_21855
SALG: BS332_16795
SKH: STH12_01689(rimK_4)
PSEO: OM33_05960
PRR: AT705_00405
PPIS: B1L02_10160
PSPO: PSPO_a0609(cofF)
PTU: PTUN_a3869(cofF)
PSEN: PNC201_06600(rimK1)
PDJ: D0907_18800
FBL: Fbal_1405 Fbal_3320
LHA: LHA_0303
LCD: clem_13645(rimK_3)
LGT: E4T54_06750
TSV: DSM104635_01004(lysX)
CBOT: ATE48_15055
THAA: CFI11_16260
NRE: BES08_00495
NOV: TQ38_005500
SMAZ: LH19_12250
SPHM: G432_12675
SSAN: NX02_01805 NX02_02790
SUFL: FIL70_03915
CMAN: A9D14_02485
MAI: MICA_511
MAN: A11S_494
BMX: BMS_2472
BCO: Bcell_3109 Bcell_3110
BHK: B4U37_16110
BBEV: BBEV_0975(rimK-2)
OIH: OB2060
TAP: GZ22_09970 GZ22_09975
VIR: X953_09135
VHL: BME96_08020 BME96_08025
VIG: BKP57_01650
VIL: CFK37_13350 CFK37_13355
VNE: CFK40_08770
VPN: A21D_03084(lysX) A21D_03085(rimK)
LAO: AOX59_06080 AOX59_06085
BSJ: UP17_17620
BMUR: ABE28_016420
PBUT: DTO10_04465
AQT: FN924_11475
GRC: GI584_04560 GI584_04585
POF: GS400_14495 GS400_14500
HSC: HVS_08550(rimK1) HVS_08555(rimK2)
CPY: Cphy_2753
ANR: Ana3638_16390 Ana3638_16395
ACEL: acsn021_27150
AWO: Awo_c26080 Awo_c26090
CBAR: PATL70BA_1083
CGV: CGLAU_09760(rimK)
ACIT: HPK19_17060 HPK19_17065
AFO: Afer_0709
WCH: wcw_1112(rimK)
SNG: SNE_A10260(rimK)
SFC: Spiaf_0383
SPER: EW093_12210
PSTY: BFS30_01295
PROC: Ptc2401_00937(lysX_1)
TAV: G4V39_06485
MJA: MJ_1001
MFE: Mefer_1229
MVU: Metvu_1301
MFS: MFS40622_1616
MIF: Metin_0765
MJH: JH146_0956
MIG: Metig_0022
MMP: MMP0170(cofF)
MMQ: MmarC5_1505
MMX: MmarC6_0780
MMZ: MmarC7_1170
MMD: GYY_00870
MMAK: MMKA1_01750(cofF)
MMAO: MMOS7_02010(cofF)
MMAD: MMJJ_09140(rimK_2)
MAE: Maeo_1379
MVN: Mevan_1175
MVO: Mvol_1166 Mvol_1455
MOK: Metok_0654
METF: CFE53_01290(cofF)
FPL: Ferp_2172
MAC: MA_1361(rimK)
MMA: MM_2347
MMAZ: MmTuc01_2397
MMJ: MSMAS_2353
MMAC: MSMAC_2094
MLS: MSLAZ_0946
MEF: MSWH1_2290
MEQ: MSWHS_2785
MHOR: MSHOH_2976
MMET: MCMEM_1893
MZH: Mzhil_0669
MPY: Mpsy_2134(rimK)
VG: 29122638(BJD26_gp120)
 » show all
Reference
  Authors
Li H, Xu H, Graham DE, White RH
  Title
Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.
  Journal
Proc Natl Acad Sci U S A 100:9785-90 (2003)
DOI:10.1073/pnas.1733391100
  Sequence
[mja:MJ_1001]

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (2069)   
   KEGG GENES (127)   
   KEGG MGENES (1512)   
   RefGene (418)   
   OC (12)   
Literature (1)   
   PubMed (1)   
All databases (2083)   

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KEGG   ENZYME: 6.3.2.32
Entry
EC 6.3.2.32                 Enzyme                                 

Name
coenzyme gamma-F420-2:alpha-L-glutamate ligase;
MJ1001;
CofF protein;
gamma-F420-2:alpha-L-glutamate ligase
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)
Sysname
L-glutamate:coenzyme gamma-F420-2 (ADP-forming)
Reaction(IUBMB)
ATP + coenzyme gamma-F420-2 + L-glutamate = ADP + phosphate + coenzyme alpha-F420-3 [RN:R09401]
Reaction(KEGG)
R09401
Substrate
ATP [CPD:C00002];
coenzyme gamma-F420-2 [CPD:C00876];
L-glutamate [CPD:C00025]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
coenzyme alpha-F420-3 [CPD:C19151]
Comment
The enzyme caps the gamma-glutamyl tail of the hydride carrier coenzyme F420 [1].
History
EC 6.3.2.32 created 2010
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K14940  gamma-F420-2:alpha-L-glutamate ligase
Genes
SON: SO_2200(rimK)
SAZ: Sama_1999
SBL: Sbal_1848
SBM: Shew185_1834
SBN: Sbal195_1882
SBP: Sbal223_2443
SBT: Sbal678_1921
SBS: Sbal117_1966
SBB: Sbal175_2505
SPC: Sputcn32_1744
SHP: Sput200_1771
SHE: Shewmr4_2195
SHM: Shewmr7_2272
SHN: Shewana3_2405
SHW: Sputw3181_2281
SHF: CEQ32_03360
SBJ: CF168_08980
SHEW: CKQ84_21855
SALG: BS332_16795
SKH: STH12_01689(rimK_4)
PSEO: OM33_05960
PRR: AT705_00405
PPIS: B1L02_10160
PSPO: PSPO_a0609(cofF)
PTU: PTUN_a3869(cofF)
PSEN: PNC201_06600(rimK1)
PDJ: D0907_18800
FBL: Fbal_1405 Fbal_3320
LHA: LHA_0303
LCD: clem_13645(rimK_3)
LGT: E4T54_06750
TSV: DSM104635_01004(lysX)
CBOT: ATE48_15055
THAA: CFI11_16260
NRE: BES08_00495
NOV: TQ38_005500
SMAZ: LH19_12250
SPHM: G432_12675
SSAN: NX02_01805 NX02_02790
SUFL: FIL70_03915
CMAN: A9D14_02485
MAI: MICA_511
MAN: A11S_494
BMX: BMS_2472
BCO: Bcell_3109 Bcell_3110
BHK: B4U37_16110
BBEV: BBEV_0975(rimK-2)
OIH: OB2060
TAP: GZ22_09970 GZ22_09975
VIR: X953_09135
VHL: BME96_08020 BME96_08025
VIG: BKP57_01650
VIL: CFK37_13350 CFK37_13355
VNE: CFK40_08770
VPN: A21D_03084(lysX) A21D_03085(rimK)
LAO: AOX59_06080 AOX59_06085
BSJ: UP17_17620
BMUR: ABE28_016420
PBUT: DTO10_04465
AQT: FN924_11475
GRC: GI584_04560 GI584_04585
POF: GS400_14495 GS400_14500
HSC: HVS_08550(rimK1) HVS_08555(rimK2)
CPY: Cphy_2753
ANR: Ana3638_16390 Ana3638_16395
ACEL: acsn021_27150
AWO: Awo_c26080 Awo_c26090
CBAR: PATL70BA_1083
CGV: CGLAU_09760(rimK)
ACIT: HPK19_17060 HPK19_17065
AFO: Afer_0709
WCH: wcw_1112(rimK)
SNG: SNE_A10260(rimK)
SFC: Spiaf_0383
SPER: EW093_12210
PSTY: BFS30_01295
PROC: Ptc2401_00937(lysX_1)
TAV: G4V39_06485
MJA: MJ_1001
MFE: Mefer_1229
MVU: Metvu_1301
MFS: MFS40622_1616
MIF: Metin_0765
MJH: JH146_0956
MIG: Metig_0022
MMP: MMP0170(cofF)
MMQ: MmarC5_1505
MMX: MmarC6_0780
MMZ: MmarC7_1170
MMD: GYY_00870
MMAK: MMKA1_01750(cofF)
MMAO: MMOS7_02010(cofF)
MMAD: MMJJ_09140(rimK_2)
MAE: Maeo_1379
MVN: Mevan_1175
MVO: Mvol_1166 Mvol_1455
MOK: Metok_0654
METF: CFE53_01290(cofF)
FPL: Ferp_2172
MAC: MA_1361(rimK)
MMA: MM_2347
MMAZ: MmTuc01_2397
MMJ: MSMAS_2353
MMAC: MSMAC_2094
MLS: MSLAZ_0946
MEF: MSWH1_2290
MEQ: MSWHS_2785
MHOR: MSHOH_2976
MMET: MCMEM_1893
MZH: Mzhil_0669
MPY: Mpsy_2134(rimK)
 » show all
Reference
1  [PMID:12909715]
  Authors
Li H, Xu H, Graham DE, White RH
  Title
Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.
  Journal
Proc Natl Acad Sci U S A 100:9785-90 (2003)
DOI:10.1073/pnas.1733391100
  Sequence
[mja:MJ_1001]
Other DBs
ExplorEnz - The Enzyme Database: 6.3.2.32
IUBMB Enzyme Nomenclature: 6.3.2.32
ExPASy - ENZYME nomenclature database: 6.3.2.32
BRENDA, the Enzyme Database: 6.3.2.32

  All links  
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (2058)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (127)   
   KEGG MGENES (1512)   
   RefGene (418)   
Protein sequence (45)   
   UniProt (12)   
   SWISS-PROT (2)   
   RefSeq(pep) (31)   
DNA sequence (44)   
   RefSeq(nuc) (38)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   InterPro (5)   
All databases (2167)   

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KEGG   REACTION: R09401
Entry
R09401                      Reaction                               

Name
L-glutamate:coenzyme gamma-F420-2 (ADP-forming)
Definition
ATP + Coenzyme F420 + L-Glutamate <=> ADP + Coenzyme F420-3 + Orthophosphate
Equation
Reaction class
RC00002  C00002_C00008
RC00064  C00025_C19151
RC00090  C00876_C19151
Enzyme
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K14940  gamma-F420-2:alpha-L-glutamate ligase [EC:6.3.2.32]
Other DBs
RHEA: 42335

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (3)   
Gene (128)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (127)   
All databases (145)   

Download RDF
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