KEGG   ORTHOLOGY: K15746Help
Entry
K15746                      KO                                     

Name
crtZ
Definition
beta-carotene 3-hydroxylase [EC:1.14.15.24]
Pathway
ko00906  Carotenoid biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00372  Abscisic acid biosynthesis, beta-carotene => abscisic acid
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00906 Carotenoid biosynthesis
    K15746  crtZ; beta-carotene 3-hydroxylase
KEGG modules [BR:ko00002]
 Pathway module
  Biosynthesis of terpenoids and polyketides
   Other terpenoid biosynthesis
    M00372  Abscisic acid biosynthesis, beta-carotene => abscisic acid
     K15746  crtZ; beta-carotene 3-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.24  beta-carotene 3-hydroxylase
     K15746  crtZ; beta-carotene 3-hydroxylase
BRITE hierarchy
Other DBs
RN: R07530 R07558 R07559 R07561 R07562 R07568 R07569 R07570 R07572 R07851 R09747
GO: 0052611
Genes
RSS: 109442727
ATH: AT4G25700(BETA-OHASE_1) AT5G52570(BETA-OHASE_2)
ALY: ARALYDRAFT_492254 ARALYDRAFT_495328
CRB: 17875800 17877995
CSAT: 104717685 104722390 104725769 104727661 104730850 104761269
EUS: EUTSA_v10014816mg EUTSA_v10025794mg
BRP: 103844746 103861586(BCH) 103863442
BNA: 106347114 106405085 106406976 106421444 106421466 106442750 106442837 106442847
BOE: 106302033 106316293 106323808 106324977
THJ: 104800269 104811957
CPAP: 110810314
GMX: 100785541(BCH2) 100802778(BCH4) 100813368(BCH5) 547758(BCH3)
LJA: Lj0g3v0299729.1(Lj0g3v0299729.1) Lj2g3v1902110.1(Lj2g3v1902110.1) Lj5g3v1988680.1(Lj5g3v1988680.1)
ADU: 107491106
AIP: 107644881
CMO: 103482780 103484113(CHXB)
VVI: 100232875(BCH1) 100268009
SLY: 544133(CrtR-b1) 544297(CrtR-b2)
CANN: 107863219(CA1) 107873401(CA2)
NTA: 107789701 107809222(CrtR-b1) 107822278(BCH2)
INI: 109189248(CHYB)
HAN: 110912807
LSV: 111918038
CCAV: 112509279
BVG: 104888376
NNU: 104595976
DOSA: Os03t0125100-01(Os03g0125100) Os04t0578400-01(Os04g0578400) Os10t0533500-00(Os10g0533500)
ATS: 109759864(LOC109759864) 109783558(LOC109783558)
PDA: 103718481
AOF: 109837875
CRE: CHLREDRAFT_164400(CHYB)
VCN: VOLCADRAFT_68369(chyB)
MNG: MNEG_1351
MPP: MICPUCDRAFT_38006(CRTR)
APRO: F751_1825
ESA: ESA_00341
PSTS: E05_04180(crtZ)
EGE: EM595_0216(crtZ)
PAM: PANA_4163(crtZ)
PLF: PANA5342_p10304(crtZ)
PAJ: PAJ_p0121(crtZ)
PAQ: PAGR_p229
PVA: Pvag_pPag30170(crtZ)
PSTW: DSJ_25955
PPU: PP_3246(crtZ)
PPF: Pput_2516
PPT: PPS_2732
PPB: PPUBIRD1_2531(crtZ)
PPI: YSA_10718
PPX: T1E_5632(crtZ)
PPUH: B479_13325
PPUT: L483_17455
PPUN: PP4_25760(crtZ)
PPUD: DW66_2991
PMON: X969_13000
PMOT: X970_12645
PEN: PSEEN3115(crtZ)
PSA: PST_3871(crtZ)
PSZ: PSTAB_3822(crtZ)
PSR: PSTAA_3964(crtZ)
PSTT: CH92_19200
ACX: Achr_15260(crtZ)
RTA: Rta_07680
SCL: sce0583(crtZ)
XAU: Xaut_4535
RVA: Rvan_0152
CAK: Caul_1710
NAR: Saro_1168
SAL: Sala_2128
SPHP: LH20_13675
SMAZ: LH19_01990
SPHU: SPPYR_3342(crtZ)
SPHI: TS85_19965
SSAN: NX02_21750
SPKC: KC8_14900
SJP: SJA_C1-06860(crtZ)
SSY: SLG_38860(crtZ)
SPMI: K663_01820
SPHB: EP837_01682(crtZ)
SPHR: BSY17_1741
SINB: SIDU_10345
SPHT: K426_03985
BLAS: BSY18_170
ELI: ELI_03325
AAY: WYH_00011
ALB: AEB_P3199
AFO: Afer_0482
AYM: YM304_38780(crtZ)
CPI: Cpin_5618
FLN: FLA_3500
SGN: SGRA_1065(crtR)
PHE: Phep_2089
MUC: MuYL_4807
CHU: CHU_2038(crtZ)
DFE: Dfer_2033
SLI: Slin_5702
FAE: FAES_0647
PSEZ: HME7025_02277(crtZ)
HSW: Hsw_1151
FLM: MY04_1511
GFO: GFO_2501(crtZ)
GFL: GRFL_0484
FJO: Fjoh_0059
FPS: FP1451(crtZ)
FBR: FBFL15_2142(crtZ)
FIN: KQS_04640(crtZ)
ZPR: ZPR_0874
MARM: YQ22_13890
CBAL: M667_09580
CBAT: M666_09505
DOK: MED134_13066(crtZ)
DDO: I597_1408
ZGA: ZOBELLIA_2972(crtZ)
MLT: VC82_2329
NDO: DDD_2395(crtZ)
POM: MED152_02565(crtZ1) MED152_02665(crtZ3)
EAO: BD94_2900
CHZ: CHSO_3057(crtZ)
WIN: WPG_0039
TJE: TJEJU_1860(crtZ)
TMAR: MARIT_0424
SPON: HME9304_02556(crtZ)
MARF: CJ739_2846
FBA: FIC_01508
FBU: UJ101_02156(crtZ)
PTO: PTO1531
CDIV: CPM_0972
SSO: SSO2906(crtZ)
SOL: Ssol_0702
SSOA: SULA_0695
SSOL: SULB_0697
SSOF: SULC_0695
SAI: Saci_1733(crtZ)
SID: M164_0447
MSE: Msed_1074
MCN: Mcup_1040
AG: AAD54243(crtZ) ACF21782(BHY) CAA70427(CA1) CAA70888(CA2)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Choi SK, Matsuda S, Hoshino T, Peng X, Misawa N
  Title
Characterization of bacterial beta-carotene 3,3'-hydroxylases, CrtZ, and P450 in astaxanthin biosynthetic pathway and adonirubin production by gene combination in Escherichia coli.
  Journal
Appl Microbiol Biotechnol 72:1238-46 (2006)
DOI:10.1007/s00253-006-0426-2
Reference
PMID:8798688
  Authors
Sun Z, Gantt E, Cunningham FX Jr
  Title
Cloning and functional analysis of the beta-carotene hydroxylase of Arabidopsis thaliana.
  Journal
J Biol Chem 271:24349-52 (1996)
DOI:10.1074/jbc.271.40.24349
  Sequence
[ath:AT4G25700]
Reference
  Authors
Linden H
  Title
Carotenoid hydroxylase from Haematococcus pluvialis: cDNA sequence, regulation and functional complementation.
  Journal
Biochim Biophys Acta 1446:203-12 (1999)
DOI:10.1016/S0167-4781(99)00088-3
  Sequence

KEGG   ENZYME: 1.14.13.129Help
Entry
EC 1.14.13.129    Obsolete  Enzyme                                 

Name
Transferred to 1.14.15.24
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Comment
Transferred entry: beta-carotene 3-hydroxylase. Now EC 1.14.15.24, beta-carotene 3-hydroxylase.
History
EC 1.14.13.129 created 2011, deleted 2017

KEGG   REACTION: R07558Help
Entry
R07558                      Reaction                               

Name
beta-carotene,reduced ferredoxin [iron-sulfur] cluster:oxygen 3-oxidoreductase
Definition
beta-Carotene + 2 Reduced ferredoxin + H+ + Oxygen <=> beta-Cryptoxanthin + 2 Oxidized ferredoxin + H2O
Equation
Comment
the first step of two-step reaction (see R09747, R07558+R07559)
Reaction class
RC00478  C02094_C08591
Enzyme
1.14.13.-       1.14.15.24      1.14.-.-
Pathway
rn00906  Carotenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00372  Abscisic acid biosynthesis, beta-carotene => abscisic acid
Orthology
K02294  beta-carotene hydroxylase [EC:1.14.13.-]
K15746  beta-carotene 3-hydroxylase [EC:1.14.15.24]
K15747  beta-ring hydroxylase [EC:1.14.-.-]
K22492  beta-carotene 3-hydroxylase [EC:1.14.15.24]
K23037  beta-carotene 4-ketolase/3-hydroxylase [EC:1.14.99.63 1.14.15.24 1.14.99.-]
Other DBs
RHEA: 30326

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