KEGG ORTHOLOGY: K15839

ORTHOLOGY: K15839

Entry

K15839                      KO

Symbol

GPSM1, AGS3

Name

G-protein signaling modulator 1

Pathway

map05030

Cocaine addiction

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09165 Substance dependence
   05030 Cocaine addiction
    K15839  GPSM1, AGS3; G-protein signaling modulator 1

Other DBs

GO:

0005096

Genes

HSA:	26086(GPSM1)

PTR:	464915(GPSM1)

GGO:	101145847(GPSM1)

PON:	100444986(GPSM1)

PPYG:

129043983(GPSM1)

NLE:	101178942(GPSM1)

HMH:	116475860(GPSM1)

SSYN:

129478686(GPSM1)

MCF:	102145199(GPSM1)

MTHB:

126936933

MNI:

105471924

CSAB:

103239632(GPSM1)

CATY:

105580565(GPSM1)

PANU:

100998349(GPSM1)

TGE:	112608372(GPSM1)

MLEU:

105543247(GPSM1)

RRO:	104669678(GPSM1)

TFN:	117099159(GPSM1)

PTEH:

111553099(GPSM1)

CANG:

105522714(GPSM1)

CJC:	100388990(GPSM1)

SBQ:	101039352(GPSM1)

CIMI:

108287320(GPSM1)

ANAN:

105712260(GPSM1)

CSYR:

103250621(GPSM1)

MMUR:

105880790(GPSM1)

LCAT:

123645792(GPSM1)

PCOQ:

105818723(GPSM1)

OGA:	100944954(GPSM1)

MMU:	67839(Gpsm1)

MCAL:

110284004(Gpsm1)

MPAH:

110318698(Gpsm1)

RNO:	246254(Gpsm1)

MCOC:

116089848(Gpsm1)

ANU:	117710135(Gpsm1)

MUN:	110550862(Gpsm1)

CGE:	100758972(Gpsm1)

MAUA:

101840211(Gpsm1)

PROB:

127222624(Gpsm1)

PLEU:

114692814(Gpsm1)

MORG:

121462913(Gpsm1)

MFOT:

126509355

AAMP:

119818664(Gpsm1)

NGI:	103741204(Gpsm1)

HGL:	101724892(Gpsm1)

CPOC:

100712752(Gpsm1)

DORD:

105995666(Gpsm1)

DSP:	122108959(Gpsm1)

NCAR:

124964637

MMMA:

107159239(Gpsm1)

OPI:	101535138(GPSM1)

TUP:	102494045(GPSM1)

GVR:	103590864(GPSM1)

CFA:	100855572(GPSM1)

CLUD:

112677436(GPSM1)

VVP:	112906948(GPSM1)

VLG:	121473710(GPSM1)

NPO:	129507644(GPSM1)

AML:	100467428(GPSM1)

UMR:	103675277(GPSM1)

UAH:	113266598(GPSM1)

UAR:	123796357(GPSM1)

ELK:

111146434

LLV:

125083031

MPUF:

101680378(GPSM1)

MNP:	132024250(GPSM1)

MLK:	131813191(GPSM1)

NVS:	122917123(GPSM1)

ORO:	101382753(GPSM1)

EJU:	114201885(GPSM1) 114203843 114203845

ZCA:	113934989(GPSM1)

MLX:	118017526(GPSM1)

NSU:	110581219(GPSM1)

LWW:	102742423(GPSM1)

FCA:	101088790(GPSM1)

PYU:	121022860(GPSM1)

PCOO:

112860478

PBG:	122475339(GPSM1)

PVIV:

125150772(GPSM1)

LRUF:

124522406

PPAD:

109258800(GPSM1)

PUC:

125923315

AJU:

106989555

HHV:	120221957(GPSM1)

BTA:	100139799(GPSM1)

BOM:	102276231(GPSM1)

BIU:	109565679(GPSM1)

BBUB:

102411854(GPSM1)

BBIS:

104988682

CHX:

102190425

OAS:	101116818(GPSM1)

BTAX:

128055986(GPSM1)

ODA:	120852144(GPSM1)

CCAD:

122442323(GPSM1)

MBEZ:

129539484(GPSM1)

SSC:	110258076(GPSM1)

CFR:	102514671(GPSM1)

CBAI:

105069733(GPSM1)

CDK:	105106022(GPSM1)

VPC:	102537368(GPSM1)

BACU:

103018828(GPSM1)

BMUS:

118897164(GPSM1)

LVE:	103069666(GPSM1)

OOR:	101285058(GPSM1)

DLE:	111177035(GPSM1)

PCAD:

102983817

PSIU:

116755752(GPSM1)

NASI:

112411517(GPSM1)

ECB:	100066325(GPSM1)

EAI:	106845552(GPSM1)

MMYO:

118655261(GPSM1)

MDT:	132212582(GPSM1)

PKL:	118707015(GPSM1)

EFUS:

103295983(GPSM1)

MNA:	107535525(GPSM1)

DRO:	112306564(GPSM1)

SHON:

118980135(GPSM1)

AJM:	119036113(GPSM1)

PDIC:

114499571(GPSM1)

PHAS:

123823542(GPSM1)

MMF:	118629919(GPSM1)

PPAM:

129079554(GPSM1)

HAI:	109381429(GPSM1)

RFQ:	117031981(GPSM1)

PALE:

102885025(GPSM1)

PGIG:

120599724(GPSM1)

PVP:	105298581(GPSM1)

RAY:	107514873(GPSM1)

MJV:	108387658(GPSM1)

TOD:	119231121(GPSM1)

SARA:

101551318(GPSM1)

SETR:

126009244(GPSM1)

LAV:	100658641(GPSM1)

TMU:

101361306

ETF:	101650802(GPSM1)

DNM:	101416981(GPSM1)

MDO:	100020642(GPSM1)

GAS:	123233614(GPSM1)

SHR:	100931535(GPSM1)

AFZ:

127550986

PCW:	110205336(GPSM1)

TVP:	118843971(GPSM1)

OAA:	107548064(GPSM1)

GGA:	417132(GPSM1)

PCOC:

116234334(GPSM1)

MGP:	100547235(GPSM1)

CJO:	107321708(GPSM1)

TPAI:

128073106(GPSM1)

LMUT:

125702451(GPSM1)

NMEL:

110406834(GPSM1)

APLA:

101790352(GPSM1)

ACYG:

106040698(GPSM1)

CATA:

118252217(GPSM1)

AFUL:

116496981(GPSM1)

TGU:	100228863(GPSM1)

SCAN:

103818948(GPSM1)

PMOA:

120512432(GPSM1)

OTC:	121337076(GPSM1)

PRUF:

121362406(GPSM1)

FAB:	101815873(GPSM1)

OMA:	130260157(GPSM1)

PHI:	102113272(GPSM1)

PMAJ:

107212091(GPSM1)

CCW:	104688357(GPSM1)

CBRC:

103623120(GPSM1)

ETL:	114059113(GPSM1)

ZAB:	102067748(GPSM1)

ZLE:	135454840(GPSM1)

ACHL:

103804917(GPSM1)

SVG:	106855423(GPSM1)

MMEA:

130582255(GPSM1)

HRT:	120761675(GPSM1)

SATI:

136369813(GPSM1)

FPG:	101910562(GPSM1)

FCH:	102046839(GPSM1)

CCRI:

104159818

NNT:

104409011

SHAB:

115616985(GPSM1)

ACUN:

113486524(GPSM1)

TALA:

104364277(GPSM1)

ACHC:

115335450(GPSM1)

HALD:

104318719

HLE:	104833839(GPSM1)

AGEN:

126051988

GCL:

127023856

CSTI:

104555713(GPSM1)

LDI:

104346028

MNB:

103771869

DPUB:

104306538(GPSM1)

AVIT:

104278860(GPSM1)

BRHI:

104500249

EGZ:	104129371(GPSM1)

NNI:	104023209(GPSM1)

PCRI:

104029628(GPSM1)

PCAO:

104043200

PADL:

103915250(GPSM1)

AFOR:

103900032(GPSM1)

FGA:

104083281

GSTE:

104261645

CLV:	102084935(GPSM1)

MUI:	104543550(GPSM1)

PGUU:

104466282(GPSM1)

PLET:

104617209(GPSM1)

EHS:

104515182

CMAC:

104485601

CUCA:

104066843(GPSM1)

TEO:	104374987(GPSM1)

BREG:

104633091 104638839

OHA:	104336604(GPSM1)

ACAR:

104523103

CPEA:

104389892(GPSM1)

CVF:	104292836(GPSM1)

RTD:	128917329(GPSM1)

AAM:	106487006(GPSM1)

AROW:

112964350(GPSM1)

TGT:	104575205(GPSM1)

DNE:	112979894(GPSM1)

SCAM:

104138222(GPSM1)

ASN:	102380609(GPSM1)

AMJ:	102572628(GPSM1)

CPOO:

109314019(GPSM1)

GGN:	109292753(GPSM1)

CMY:	102931915(GPSM1)

CCAY:

125623292(GPSM1)

DCC:	119844113(GPSM1)

CPIC:

101939280(GPSM1)

TST:	117889357(GPSM1)

CABI:

116817439(GPSM1)

MRV:	120387013(GPSM1)

ASAO:

132763735(GPSM1)

SUND:

121936270(GPSM1)

CTIG:

120317509(GPSM1)

PGUT:

117671279(GPSM1) 132709957

APRI:

131186294(GPSM1)

PTEX:

113448441(GPSM1)

NSS:	113427504(GPSM1)

VKO:	123035149(GPSM1)

PMUA:

114589095(GPSM1)

PRAF:

128406380(GPSM1)

ZVI:	118083973(GPSM1) 118088504

HCG:	128339037(GPSM1)

GJA:	107115407(GPSM1)

STOW:

125441664(GPSM1)

EMC:	129341932(GPSM1)

XLA:	108699905 446656(gpsm1.L)

XTR:	100125000(gpsm1)

NPR:	108793118(GPSM1)

RTEM:

120913846(GPSM1)

BBUF:

120977079(GPSM1)

BGAR:

122946494(GPSM1)

MUO:	115473024(GPSM1)

GSH:	117368505(GPSM1)

DRE:	493623(gpsm1b)

SRX:	107741501 107744057

SANH:

107674924 107704761

SGH:	107562333 107597941

CAUA:

113068065(gpsm1) 113086758

CGIB:

127957236 127989490

PTET:

122344876(gpsm1b)

LROH:

127165806(gpsm1b)

OMC:	131540356(gpsm1b)

PPRM:

120471898(gpsm1b)

RKG:	130089437(gpsm1b)

MAMB:

125267873(gpsm1b)

CIDE:

127512027

CERY:

137034288(gpsm1b)

MASI:

127426139 127435688

TROS:

130567421(gpsm1b)

TDW:	130419468(gpsm1b)

MANU:

129440772(gpsm1b)

IPU:	108260141(gpsm1b)

IFU:	128603784(gpsm1b)

PHYP:

113531092(gpsm1)

SMEO:

124378965(gpsm1b)

TFD:	113650883(gpsm1b)

TVC:	132840910(gpsm1b)

TRN:	134302992(gpsm1b)

AMEX:

103029351(gpsm1b)

CMAO:

118814841(gpsm1b)

EEE:	113587247(gpsm1)

CHAR:

105888486(gpsm1b)

TRU:	101071035(gpsm1)

TFS:	130516984(gpsm1b)

TNG:	GSTEN00034674G001

LCO:	104924179(gpsm1)

NCC:	104961829(gpsm1)

TBEN:

117476423(gpsm1b)

CGOB:

115016448(gpsm1)

PGEO:

117455841(gpsm1b)

GACU:

117539093(gpsm1b)

EMAC:

134868344(gpsm1b)

ELY:	117270021(gpsm1b)

EFO:	125906142(gpsm1b)

PLEP:

121959831(gpsm1b)

SLUC:

116062890(gpsm1b)

ECRA:

117959799(gpsm1b)

ESP:	116704434(gpsm1)

PFLV:

114570828

GAT:	120831596(gpsm1b)

PPUG:

119226828(gpsm1b)

AFB:	129102219(gpsm1b)

CLUM:

117740629(gpsm1b)

PSWI:

130205344(gpsm1b)

MSAM:

119914296(gpsm1b)

SCHU:

122865513(gpsm1b)

CUD:	121525093(gpsm1b)

ALAT:

119030233(gpsm1b)

MZE:	101485436(gpsm1)

ONL:	100696478(gpsm1)

OAU:	116331748(gpsm1b)

OLA:	101171349(gpsm1)

OML:	112162757(gpsm1b)

CSAI:

133454905(gpsm1b)

XMA:	102236604(gpsm1)

XCO:	114149352(gpsm1)

XHE:	116724966(gpsm1)

PRET:

103473842(gpsm1)

PFOR:

103142773 103142777

PLAI:

106942185 106961641(gpsm1)

PMEI:

106910217 106911279

GAF:	122819658(gpsm1b)

PPRL:

129366542(gpsm1b)

CVG:	107096157(gpsm1)

CTUL:

119789815(gpsm1b)

GMU:	124872681(gpsm1b)

NFU:	107374662(gpsm1)

KMR:	108230865(gpsm1b)

ALIM:

106518213(gpsm1)

NWH:	119424782(gpsm1b)

AOCE:

111577480(gpsm1)

MCEP:

124996842(gpsm1b)

CSEM:

103390193

POV:	109626431(gpsm1)

SSEN:

122758126(gpsm1b)

HHIP:

117771627(gpsm1b)

HSP:	118125743(gpsm1b)

PPLT:

128424873(gpsm1b)

SMAU:

118284811(gpsm1b)

LCF:	108874101(gpsm1b)

SDU:	111238511(gpsm1)

SLAL:

111664798(gpsm1)

XGL:	120806329(gpsm1b)

HCQ:	109528231(gpsm1)

SSCV:

125979609

SBIA:

133491123(gpsm1b)

PEE:	133413956(gpsm1b)

PTAO:

133490046(gpsm1b)

BPEC:

110160549(gpsm1)

MALB:

109960618

BSPL:

114866879(gpsm1b)

SJO:	128380495(gpsm1b)

SASA:

106563264 106565740

STRU:

115159538 115204095

OTW:	112219330 112231016

OMY:	110509822 110523609

OGO:	124006983 124048938

ONE:	115101187 115123094

OKI:	109874129 109876021

OKE:	118385277 118387547

SALP:

111961588 111964046

SNH:	120021255 120026185

CCLU:

121541692 121582483

ELS:	105015117(gpsm1)

AANG:

118206476 118212712(gpsm1b)

LOC:	102694250(gpsm1)

PSPA:

121303561 121307066

ARUT:

117397001(gpsm1b)

PSEX:

120535087(gpsm1b)

RTP:	109916058(gpsm1b)

CPLA:

122564954(gpsm1b)

HOC:	132825917(gpsm1b)

LERI:

PMEO:

DPOL:

HSY:

Reference

PMID:10559191

Authors

Takesono A, Cismowski MJ, Ribas C, Bernard M, Chung P, Hazard S 3rd, Duzic E, Lanier SM

Title

Receptor-independent activators of heterotrimeric G-protein signaling pathways.

Journal

J Biol Chem 274:33202-5 (1999)
DOI:10.1074/jbc.274.47.33202

Sequence

[rno:246254]

Reference

PMID:20700046

Authors

Bowers MS

Title

Activators of G-protein signaling 3: a drug addiction molecular gateway.

Journal

Behav Pharmacol 21:500-13 (2010)
DOI:10.1097/FBP.0b013e32833dcfa5

Reference

PMID:15207906

Authors

Lanier SM

Title

AGS proteins, GPR motifs and the signals processed by heterotrimeric G proteins.

Journal

Biol Cell 96:369-72 (2004)
DOI:10.1016/j.biolcel.2004.03.012

All links

Ontology (2)   
   KEGG BRITE (1)   
   GO (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (712)   
   KEGG GENES (403)   
   KEGG MGENES (145)   
   RefGene (161)   
   OC (3)   
Literature (3)   
   PubMed (3)   
All databases (719)   

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