KEGG   ORTHOLOGY: K15884Help
Entry
K15884                      KO                                     

Name
snoaE, aknE1
Definition
bifunctional aromatase (cyclase/dehydratase) [EC:4.2.1.-]
Pathway
ko01056  Biosynthesis of type II polyketide backbone
ko01100  Metabolic pathways
ko01130  Biosynthesis of antibiotics
Module
M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    K15884  snoaE, aknE1; bifunctional aromatase (cyclase/dehydratase)
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.-  
     K15884  snoaE, aknE1; bifunctional aromatase (cyclase/dehydratase)
BRITE hierarchy
Other DBs
RN: R09266 R09267
Genes
AG: AAA65203(dpsF) AAF70103(aknE1) CAA12012(snoaE)
TaxonomyKoalaUniProt
Reference
PMID:8668120
  Authors
Ylihonko K, Tuikkanen J, Jussila S, Cong L, Mantsala P
  Title
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.
  Journal
Mol Gen Genet 251:113-20 (1996)
DOI:10.1007/BF02172908
  Sequence
Reference
  Authors
Raty K, Kantola J, Hautala A, Hakala J, Ylihonko K, Mantsala P
  Title
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.
  Journal
Gene 293:115-22 (2002)
DOI:10.1016/S0378-1119(02)00699-6
  Sequence

KEGG   REACTION: R09267Help
Entry
R09267                      Reaction                               

Definition
7,9,12-Decaketide intermediate 5 <=> 7,9,12-Decaketide intermediate 6 + 2 H2O
Equation
Reaction class
RC02546  C18334_C18335
Enzyme
4.2.1.-
Pathway
rn01056  Biosynthesis of type II polyketide backbone
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Orthology
K15884  bifunctional aromatase (cyclase/dehydratase) [EC:4.2.1.-]

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