KEGG   ORTHOLOGY: K15892Help
Entry
K15892                      KO                                     

Name
FOLK
Definition
farnesol kinase [EC:2.7.1.216]
Pathway
ko00900  Terpenoid backbone biosynthesis
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K15892  FOLK; farnesol kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.216  farnesol kinase
     K15892  FOLK; farnesol kinase
BRITE hierarchy
Other DBs
RN: R09849
GO: 0052669
Genes
ATH: AT5G58560(FOLK)
ALY: ARALYDRAFT_332145
CRB: 17875624 17886534
CSAT: 104698976 104711386 104726429 104735756 104761955 104780712
EUS: EUTSA_v10014180mg
BRP: 103845287 103856674 103856907
BNA: 106376298 106385189 106385190 106420546 106435924 106435934
BOE: 106313208 106334947 106334948
RSZ: 108823783 108848087 108848088
THJ: 104799389 104799865
CPAP: 110823862
CIT: 102607196
TCC: 18590992
GMX: 100793696
GSJ: 114397687
VRA: 106752668
VAR: 108341074
VUN: 114187077
CCAJ: 109814795
LJA: Lj0g3v0022429.1(Lj0g3v0022429.1) Lj0g3v0338869.1(Lj0g3v0338869.1)
ADU: 107473329
AIP: 107648557
LANG: 109352111
FVE: 101312326
RCN: 112166567
PPER: 18773060
PMUM: 103321386
PAVI: 110758741
MDM: 103419955
PXB: 103958984
ZJU: 107411489
CSV: 101220953
CMO: 103497053
MCHA: 111018992
RCU: 8272401
JCU: 105639148
HBR: 110634309
MESC: 110605789
JRE: 108996986
QSU: 112003510
SLY: 101252619
SPEN: 107029162
SOT: 102606110
NSY: 104237922
NAU: 109214544
INI: 109164267
CCAV: 112518182
BVG: 104903117
NNU: 104602694
OSA: 4327435
DOSA: Os01t0832000-01(Os01g0832000) Os11t0105800-01(Os11g0105800) Os12t0105500-01(Os12g0105500)
ATS: 109769583(LOC109769583) 109780312(LOC109780312) 109780318(LOC109780318)
ZMA: 100191275(pco135182)
EGU: 105036025
MUS: 103999851
DCT: 110098089
AOF: 109829993
ATR: 18437155
APRO: F751_5656
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Fitzpatrick AH, Bhandari J, Crowell DN
  Title
Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis.
  Journal
Plant J 66:1078-88 (2011)
DOI:10.1111/j.1365-313X.2011.04572.x
  Sequence
[ath:AT5G58560]

KEGG   ENZYME: 2.7.1.216Help
Entry
EC 2.7.1.216                Enzyme                                 

Name
farnesol kinase;
FOLK (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
CTP:(2E,6E)-farnesol phosphotransferase
Reaction(IUBMB)
CTP + (2E,6E)-farnesol = CDP + (2E,6E)-farnesyl phosphate [RN:R09849]
Reaction(KEGG)
Substrate
CTP [CPD:C00063];
(2E,6E)-farnesol [CPD:C01126]
Product
CDP [CPD:C00112];
(2E,6E)-farnesyl phosphate [CPD:C20121]
Comment
The enzyme, found in plants and animals, can also use other nucleotide triphosphates as phosphate donor, albeit less efficiently. The plant enzyme can also use geraniol and geranylgeraniol as substrates with lower activity, but not farnesyl phosphate (cf. EC 2.7.4.32, farnesyl phosphate kinase) [2].
History
EC 2.7.1.216 created 2017
Pathway
ec00900  Terpenoid backbone biosynthesis
ec01130  Biosynthesis of antibiotics
Orthology
K15892  farnesol kinase
Genes
ATH: AT5G58560(FOLK)
ALY: ARALYDRAFT_332145
CRB: 17875624 17886534
CSAT: 104698976 104711386 104726429 104735756 104761955 104780712
EUS: EUTSA_v10014180mg
BRP: 103845287 103856674 103856907
BNA: 106376298 106385189 106385190 106420546 106435924 106435934
BOE: 106313208 106334947 106334948
RSZ: 108823783 108848087 108848088
THJ: 104799389 104799865
CPAP: 110823862
CIT: 102607196
TCC: 18590992
GMX: 100793696
GSJ: 114397687
VRA: 106752668
VAR: 108341074
VUN: 114187077
CCAJ: 109814795
LJA: Lj0g3v0022429.1(Lj0g3v0022429.1) Lj0g3v0338869.1(Lj0g3v0338869.1)
ADU: 107473329
AIP: 107648557
LANG: 109352111
FVE: 101312326
RCN: 112166567
PPER: 18773060
PMUM: 103321386
PAVI: 110758741
MDM: 103419955
PXB: 103958984
ZJU: 107411489
CSV: 101220953
CMO: 103497053
MCHA: 111018992
RCU: 8272401
JCU: 105639148
HBR: 110634309
MESC: 110605789
JRE: 108996986
QSU: 112003510
SLY: 101252619
SPEN: 107029162
SOT: 102606110
NSY: 104237922
NAU: 109214544
INI: 109164267
CCAV: 112518182
BVG: 104903117
NNU: 104602694
OSA: 4327435
DOSA: Os01t0832000-01(Os01g0832000) Os11t0105800-01(Os11g0105800) Os12t0105500-01(Os12g0105500)
ATS: 109769583(LOC109769583) 109780312(LOC109780312) 109780318(LOC109780318)
ZMA: 100191275(pco135182)
EGU: 105036025
MUS: 103999851
DCT: 110098089
AOF: 109829993
ATR: 18437155
APRO: F751_5656
 » show all
Taxonomy
Reference
1  [PMID:9606952]
  Authors
Bentinger M, Grunler J, Peterson E, Swiezewska E, Dallner G
  Title
Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase.
  Journal
Arch Biochem Biophys 353:191-8 (1998)
DOI:10.1006/abbi.1998.0611
Reference
2  [PMID:21395888]
  Authors
Fitzpatrick AH, Bhandari J, Crowell DN.
  Title
Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis.
  Journal
Plant J 66:1078-88 (2011)
DOI:10.1111/j.1365-313X.2011.04572.x
  Sequence
[ath:AT5G58560]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.216
IUBMB Enzyme Nomenclature: 2.7.1.216
ExPASy - ENZYME nomenclature database: 2.7.1.216
BRENDA, the Enzyme Database: 2.7.1.216

KEGG   REACTION: R09849Help
Entry
R09849                      Reaction                               

Name
CTP:2-trans,6-trans-farnesol O-phosphotransferase
Definition
(2E,6E)-Farnesol + CTP <=> trans,trans-Farnesyl phosphate + CDP
Equation
Comment
farnesol kinase
ATP, GTP and UTP can act as phosphate-donor
Reaction class
RC00002  C00063_C00112
RC00017  C01126_C20121
Enzyme
Pathway
rn00900  Terpenoid backbone biosynthesis
rn01130  Biosynthesis of antibiotics
Orthology
K15892  farnesol kinase [EC:2.7.1.216]
Other DBs
RHEA: 51683

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