KEGG ORTHOLOGY: K15926

ORTHOLOGY: K15926

Entry

K15926                      KO

Symbol

jadI

Name

cyclase

Pathway

map01057

Biosynthesis of type II polyketide products

map01110

Biosynthesis of secondary metabolites

Reaction

R09340

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K15926  jadI; cyclase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K15926  jadI; cyclase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Nonaketide PKS
     K15926  jadI; cyclase

Genes

PBRU:

LZC95_37895

PRUE:

LVJ94_37705 LVJ94_41870

PALJ:

LZC94_46810

NBR:	O3I_007440

NVU:	V7968_14830

SFI:

SFUL_4001

SANL:

KZO11_29475

SCYE:

R2B67_24740

SSX:	SACTE_6345

SVE:

SVEN_5976

SALS:

SLNWT_5120

SVT:	SVTN_28590

SLD:

T261_6829

SXI:	SXIM_35850

STRC:

AA958_30250

SAMB:

SAM23877_0197(alpI) SAM23877_7476(alpI)

SCZ:	ABE83_16250

SCX:	AS200_01430

SPHW:

SALU:

SALL:

STRD:

SALJ:

SMD11_6043(whiEVII)

SLX:	SLAV_40250(tcmI2)

SNZ:	DC008_13185

SDX:	C4B68_09590

SGD:	ELQ87_00810

SCYA:

EJ357_34785

SNQ:	CP978_29755

SHAW:

CEB94_23565

SRK:	FGW37_04250

SFY:	GFH48_20460

SAQU:

EJC51_31350

SCAV:

CVT27_18205

SPAC:

B1H29_00835 B1H29_36225

SCHA:

CP983_27880

SSPB:

CP982_19010

SNF:	JYK04_04005(tcmI_2) JYK04_04011(tcmI_3)

SCHF:

IPT68_15435

SHAR:

HUT13_24885

SCYG:

S1361_29850(tcmI2)

SMOB:

SROI:

SACT:

SMAO:

SDEC:

SDRZ:

STUD:

SARG:

SLAI:

SMIB:

SCAJ:

STRL:

STSD:

HEP87_27705 HEP87_54605

SRPZ:

SGLY:

SCAT:

STBR:

STAC:

SSOC:

STRJ:

KCH:	O1G21_22130

ABRY:

NYE86_15475 NYE86_15930

AREV:

RVR_1653 RVR_2902 RVR_8895

TFU:

Tfu_1217

AWS:	ACN3XK_69280

NGN:	LCN96_42605

AORI:

APRT:

AMYS:

PSEQ:

PECQ:

SESP:

SSYI:

SACX:

STP:	Strop_2193

DAUR:

Daura_28655

NHY:	JQS43_06240

CAI:

Caci_3545

» show all

Reference

PMID:17268612

Authors

Hertweck C, Luzhetskyy A, Rebets Y, Bechthold A

Title

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork.

Journal

Nat Prod Rep 24:162-90 (2007)
DOI:10.1039/b507395m

Reference

PMID:20486694

Authors

Kharel MK, Pahari P, Lian H, Rohr J

Title

Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic.

Journal

Org Lett 12:2814-7 (2010)
DOI:10.1021/ol1009009

Reference

Authors

Kulowski K, Wendt-Pienkowski E, Han L, Yang K, Vining LC, Hutchinson CR.

Title

Functional characterization of the jadI gene as a cyclase forming angucyclinones.

Journal

J Am Chem Soc 121:1786-94 (1999)
DOI:10.1021/ja982707f

Sequence

[sve:SVEN_5976]

All links

Gene (5)   
   MGENES (4)   
   OC (1)   
All databases (5)   

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