KEGG   ORTHOLOGY: K15930Help
Entry
K15930                      KO                                     

Name
lndM2
Definition
bifunctional oxygenase/reductase
Pathway
ko01057  Biosynthesis of type II polyketide products
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K15930  lndM2; bifunctional oxygenase/reductase
BRITE hierarchy
Other DBs
RN: R06656 R09346
Genes
SSX: SACTE_6351
SFI: SFUL_4007
AG: AAT64432(lndM2)
TaxonomyKoalaUniProt
Reference
  Authors
Zhu L, Ostash B, Rix U, Nur-E-Alam M, Mayers A, Luzhetskyy A, Mendez C, Salas JA, Bechthold A, Fedorenko V, Rohr J
  Title
Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycinone.
  Journal
J Org Chem 70:631-8 (2005)
DOI:10.1021/jo0483623
  Sequence

KEGG   REACTION: R06656Help
Entry
R06656                      Reaction                               

Definition
Tetrangomycin <=> Rabelomycin
Equation
Comment
bifunctional oxygenase-reductase, lndM2
Reaction class
RC00046  C12396_C12402
Pathway
rn01057  Biosynthesis of type II polyketide products
rn01130  Biosynthesis of antibiotics
Orthology
K15930  bifunctional oxygenase/reductase

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