KEGG   ORTHOLOGY: K15948
Entry
K15948            Tight     KO                                     
Symbol
aknK
Name
aclacinomycin-T 2-deoxy-L-fucose transferase [EC:2.4.1.327]
Pathway
map01057  Biosynthesis of type II polyketide products
map01110  Biosynthesis of secondary metabolites
Reaction
R09332  dTDP-2-deoxy-beta-L-fucose:aclacinomycin-T 2-deoxy-alpha-L-fucosyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K15948  aknK; aclacinomycin-T 2-deoxy-L-fucose transferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.327  aclacinomycin-T 2-deoxy-L-fucose transferase
     K15948  aknK; aclacinomycin-T 2-deoxy-L-fucose transferase
Other DBs
COG: COG1819
CAZy: GT1
Genes
AG: AAF70102(aknK)
Reference
PMID:15078101
  Authors
Lu W, Leimkuhler C, Oberthur M, Kahne D, Walsh CT
  Title
AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A.
  Journal
Biochemistry 43:4548-58 (2004)
DOI:10.1021/bi035945i
  Sequence
[ag:AAF70102]
Reference
PMID:17685523
  Authors
Leimkuhler C, Fridman M, Lupoli T, Walker S, Walsh CT, Kahne D
  Title
Characterization of rhodosaminyl transfer by the AknS/AknT glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A.
  Journal
J Am Chem Soc 129:10546-50 (2007)
DOI:10.1021/ja072909o

  All links  
Ontology (2)   
   COG (1)   
   CAZY (1)   
All databases (2)   

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