KEGG   ORTHOLOGY: K15950
Entry
K15950            Tight     KO                                     

Name
dnrF, rdmE
Definition
aklavinone 12-hydroxylase [EC:1.14.13.180]
Pathway
ko01057  Biosynthesis of type II polyketide products
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K15950  dnrF, rdmE; aklavinone 12-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.180  aklavinone 12-hydroxylase
     K15950  dnrF, rdmE; aklavinone 12-hydroxylase
Other DBs
RN: R06683
Genes
AG: AAA83424(rdmE) AAC43342(dnrF)
Reference
  Authors
Niemi J, Wang Y, Airas K, Ylihonko K, Hakala J, Mantsala P
  Title
Characterization of aklavinone-11-hydroxylase from Streptomyces purpurascens.
  Journal
Biochim Biophys Acta 1430:57-64 (1999)
DOI:10.1016/S0167-4838(98)00265-9
  Sequence
Reference
PMID:7773378
  Authors
Filippini S, Solinas MM, Breme U, Schluter MB, Gabellini D, Biamonti G, Colombo AL, Garofano L
  Title
Streptomyces peucetius daunorubicin biosynthesis gene, dnrF: sequence and heterologous expression.
  Journal
Microbiology 141 ( Pt 4):1007-16 (1995)
DOI:10.1099/13500872-141-4-1007
  Sequence

DBGET integrated database retrieval system