KEGG   ORTHOLOGY: K15954
Entry
K15954            Tight     KO                                     

Name
dnrK, dauK
Definition
carminomycin 4-O-methyltransferase [EC:2.1.1.292]
Pathway
ko01057  Biosynthesis of type II polyketide products
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K15954  dnrK, dauK; carminomycin 4-O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.292  carminomycin 4-O-methyltransferase
     K15954  dnrK, dauK; carminomycin 4-O-methyltransferase
Other DBs
RN: R06687 R06693
Genes
AG: AAA26712(dnrK) AAB16938(dauK)
Reference
PMID:9098063
  Authors
Dickens ML, Priestley ND, Strohl WR
  Title
In vivo and in vitro bioconversion of epsilon-rhodomycinone glycoside to doxorubicin: functions of DauP, DauK, and DoxA.
  Journal
J Bacteriol 179:2641-50 (1997)
DOI:10.1128/JB.179.8.2641-2650.1997
  Sequence
Reference
PMID:8509343
  Authors
Madduri K, Torti F, Colombo AL, Hutchinson CR
  Title
Cloning and sequencing of a gene encoding carminomycin 4-O-methyltransferase from Streptomyces peucetius and its expression in Escherichia coli.
  Journal
J Bacteriol 175:3900-4 (1993)
DOI:10.1128/JB.175.12.3900-3904.1993
  Sequence
Reference
  Authors
Malla S, Niraula NP, Singh B, Liou K, Sohng JK
  Title
Limitations in doxorubicin production from Streptomyces peucetius.
  Journal
Microbiol Res 165:427-35 (2010)
DOI:10.1016/j.micres.2009.11.006

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