KEGG   ORTHOLOGY: K15959Help
Entry
K15959                      KO                                     

Name
mtmMI
Definition
O-methyltransferase [EC:2.1.1.-]
Pathway
ko01057  Biosynthesis of type II polyketide products
ko01100  Metabolic pathways
ko01130  Biosynthesis of antibiotics
Module
M00782  Mithramycin biosynthesis, 4-demethylpremithramycinone => mithramycin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K15959  mtmMI; O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-  
     K15959  mtmMI; O-methyltransferase
BRITE hierarchy
Other DBs
RN: R06715
Genes
AG: CAK50791(mtmMI)
TaxonomyKoalaUniProt
Reference
  Authors
Lozano MJ, Remsing LL, Quiros LM, Brana AF, Fernandez E, Sanchez C, Mendez C, Rohr J, Salas JA
  Title
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.
  Journal
J Biol Chem 275:3065-74 (2000)
DOI:10.1074/jbc.275.5.3065
  Sequence

KEGG   REACTION: R06715Help
Entry
R06715                      Reaction                               

Name
S-adenosyl-L-methionine:4-demethylpremithramycinone O-methyltransferase
Definition
4-Demethylpremithramycinone + S-Adenosyl-L-methionine <=> Premithramycinone + S-Adenosyl-L-homocysteine
Equation
Comment
O-methyltransferase, mtmMI
Reaction class
RC00003  C00019_C00021
RC00466  C12382_C12383
Enzyme
2.1.1.-
Pathway
rn01057  Biosynthesis of type II polyketide products
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Module
M00782  Mithramycin biosynthesis, 4-demethylpremithramycinone => mithramycin
Orthology
K15959  O-methyltransferase [EC:2.1.1.-]

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