KEGG   ORTHOLOGY: K15965Help
Entry
K15965                      KO                                     

Name
mtmGII
Definition
glycosyltransferase [EC:2.4.1.-]
Pathway
ko01057  Biosynthesis of type II polyketide products
ko01100  Metabolic pathways
ko01130  Biosynthesis of antibiotics
Module
M00782  Mithramycin biosynthesis, 4-demethylpremithramycinone => mithramycin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K15965  mtmGII; glycosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.-  
     K15965  mtmGII; glycosyltransferase
BRITE hierarchy
Other DBs
RN: R09352
CAZy: GT1
Genes
AG: CAK50792(mtmGII)
TaxonomyKoalaUniProt
Reference
  Authors
Nur-e-Alam M, Mendez C, Salas JA, Rohr J
  Title
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.
  Journal
Chembiochem 6:632-6 (2005)
DOI:10.1002/cbic.200400309
Reference
PMID:9733697
  Authors
Fernandez E, Weissbach U, Sanchez Reillo C, Brana AF, Mendez C, Rohr J, Salas JA
  Title
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.
  Journal
J Bacteriol 180:4929-37 (1998)
  Sequence

KEGG   REACTION: R09352Help
Entry
R09352                      Reaction                               

Name
dTDP-D-olivose:3A-deolivosylpremithramycin-B D-olivosyltransferase
Definition
3A-Deolivosylpremithramycin B + dTDP-D-olivose <=> Premithramycin B + dTDP
Equation
Reaction class
RC00005  C00363_C11923
RC00049  C12388_C18710
Enzyme
2.4.1.-
Pathway
rn01057  Biosynthesis of type II polyketide products
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Module
M00782  Mithramycin biosynthesis, 4-demethylpremithramycinone => mithramycin
Orthology
K15965  glycosyltransferase [EC:2.4.1.-]

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