Entry |
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Name |
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Definition |
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Pathway |
ko01057 | Biosynthesis of type II polyketide products |
ko01110 | Biosynthesis of secondary metabolites |
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Module |
M00783 | Tetracenomycin C/8-demethyltetracenomycin C biosynthesis, tetracenomycin F2 => tetracenomycin C/8-demethyltetracenomycin C |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01057 Biosynthesis of type II polyketide products
K15969 tcmH; tetracenomycin F1 monooxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
1.13.12.21 tetracenomycin-F1 monooxygenase
K15969 tcmH; tetracenomycin F1 monooxygenase
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Other DBs |
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Genes |
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Reference |
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Authors |
Summers RG, Wendt-Pienkowski E, Motamedi H, Hutchinson CR |
Title |
The tcmVI region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens encodes the tetracenomycin F1 monooxygenase, tetracenomycin F2 cyclase, and, most likely, a second cyclase. |
Journal |
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Sequence |
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Reference |
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Authors |
Shen B, Hutchinson CR |
Title |
Tetracenomycin F1 monooxygenase: oxidation of a naphthacenone to a naphthacenequinone in the biosynthesis of tetracenomycin C in Streptomyces glaucescens. |
Journal |
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