KEGG   ORTHOLOGY: K15982
Entry
K15982                      KO                                     
Symbol
kshA
Name
3-ketosteroid 9alpha-monooxygenase subunit A [EC:1.14.15.30]
Pathway
map00984  Steroid degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
R09860  androsta-1,4-diene-3,17-dione,[reduced ferredoxin]:oxygen oxidoreductase (9alpha-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K15982  kshA; 3-ketosteroid 9alpha-monooxygenase subunit A
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.30  3-ketosteroid 9alpha-monooxygenase
     K15982  kshA; 3-ketosteroid 9alpha-monooxygenase subunit A
Other DBs
COG: COG4638
Genes
RGL: CS053_01930
VAF: D1115_23260
PRE: PCA10_12240(kshA)
PFUW: KF707C_11570
PPUT: L483_14320
PPUN: PP4_26740(kshA)
PVR: PverR02_11735
PPUU: PputUW4_01666
PKC: PKB_4313(ksha1) PKB_4338(ksha3)
PFZ: AV641_09605
PSET: THL1_1304
PSIL: PMA3_11875
PTAE: NCTC10697_01839(kshA)
SPL: Spea_2121
SHL: Shal_2093
PHA: PSHAa2137
PTN: PTRA_a2590(kshA)
PNG: PNIG_a2784(kshA)
ALCA: ASALC70_02445(kshA)
AXE: P40_21405
REH: H16_B0672(hcaE)
CNC: CNE_2c06190(kshA) CNE_BB1p00120(kshA)
CGD: CR3_2920(kshA)
BMA: BMAA1220
BMAL: DM55_4293
BMAE: DM78_3877
BMAQ: DM76_3245
BMAI: DM57_10905
BMAF: DM51_4883
BMAZ: BM44_4256
BMAB: BM45_3379
BPS: BPSS0996
BPSE: BDL_4290
BPSM: BBQ_5138
BPSU: BBN_4458
BPSD: BBX_6131
BPK: BBK_6151
BPSH: DR55_4337
BPSA: BBU_5033
BPSO: X996_4235
BUT: X994_6124
BCJ: BCAM1620
BCEN: DM39_3466 DM39_6233(kshA)
BCEO: I35_5481
BCED: DM42_6338(kshA)
BCON: NL30_04080
BTEI: WS51_05735
BMEC: WJ16_26825
BFN: OI25_4592
CABA: SBC2_48980(kshA)
CTES: O987_07520
THAG: CKCBHOJB_02279(kshA)
MTU: Rv3526(kshA)
MTV: RVBD_3526
MRA: MRA_3565
MTUR: CFBS_3742
MTD: UDA_3526
MTUC: J113_24655
MTUE: J114_18850
MTUH: I917_24735
MTUL: TBHG_03466
MTUT: HKBT1_3727
MTUU: HKBT2_3736
MBO: BQ2027_MB3556(ksha)
MBB: BCG_3590
MBT: JTY_3591
MBX: BCGT_3389
MAF: MAF_35380
MMIC: RN08_3901
MORY: MO_003682(kshA)
MLP: MLM_0777
MPSE: MPSD_19540 MPSD_52140(kshA)
MSHO: MSHO_04870(kshA) MSHO_52600
MHAD: B586_04665
MBAI: MB901379_01756(kshA_1) MB901379_04408(kshA_3)
MLJ: MLAC_00150(kshA_1) MLAC_47870(kshA_2)
MSHJ: MSHI_39140
MPHL: MPHLCCUG_00577(kshA_1) MPHLCCUG_00595(kshA_2) MPHLCCUG_01870(kshA_3) MPHLCCUG_01926(kshA_4) MPHLCCUG_02604(kshA_6)
MTHN: 4412656_00372(kshA_2) 4412656_00943(kshA_4) 4412656_01450(kshA_5) 4412656_03259(kshA_6) 4412656_04042(kshA_8)
MHAS: MHAS_00793(kshA_2) MHAS_00844(kshA_3) MHAS_02479(kshA_4) MHAS_03041(kshA_5) MHAS_03182(kshA_7) MHAS_03697(kshA_8) MHAS_03711(kshA_9)
MAUU: NCTC10437_01869(kshA_1) NCTC10437_02719(kshA_2) NCTC10437_03541(kshA_3) NCTC10437_04973(kshA_5) NCTC10437_04990(kshA_6)
MMAG: MMAD_02700 MMAD_47870(kshA)
MFLV: NCTC10271_00524(kshA_1) NCTC10271_02165(kshA_2) NCTC10271_03524(kshA_5) NCTC10271_03628(kshA_6)
MSAL: DSM43276_00643(kshA_1) DSM43276_03419(kshA_2) DSM43276_04014(kshA_3)
MTER: 4434518_01527(kshA_1) 4434518_03344(kshA_2) 4434518_03640(kshA_3)
ASD: AS9A_0922(kshA)
NFR: ERS450000_00679(kshA_1) ERS450000_00697(kshA_2) ERS450000_01849(kshA_3) ERS450000_02931(kshA_4) ERS450000_03761(kshA_5)
NAD: NCTC11293_01248(kshA_1) NCTC11293_04392(kshA_2)
RER: RER_07540(kshA) RER_09150(kshA2) RER_13800(kshA) RER_51130(kshA)
ROP: ROP_22170(kshA) ROP_44530(kshA) ROP_58730(kshA2)
RRT: 4535765_00581(kshA_1) 4535765_00622(kshA_2) 4535765_04053(kshA_4)
RCR: NCTC10994_02098(kshA_1) NCTC10994_02139(kshA_2) NCTC10994_03234(kshA_3) NCTC10994_03286(kshA_4) NCTC10994_03312(kshA_5)
GPO: GPOL_c41100(kshA1) GPOL_c41200(kshA2) GPOL_c46160
GOR: KTR9_0819(kshA) KTR9_4196
GRU: GCWB2_04170(kshA1) GCWB2_11625(kshA2) GCWB2_21605(kshA4)
GOM: D7316_02031(kshA_1) D7316_02456(kshA_2) D7316_02565(kshA_3) D7316_03108(kshA_4)
TPR: Tpau_3849
SALU: DC74_7441
SALL: SAZ_38410
SLX: SLAV_27410(kshA)
LMOI: VV02_06590
NCA: Noca_2518
NDK: I601_0574(kshA_1) I601_3444(kshA_2)
TCU: Tcur_3509
FAL: FRAAL3502
AMD: AMED_2519
AMN: RAM_12805
AMM: AMES_2491
AMZ: B737_2492
AOI: AORI_2481
AJA: AJAP_26420(kshA)
AMYY: YIM_14435(kshA1) YIM_36740(kshA2)
AORI: SD37_13470
KAL: KALB_5125
SAQ: Sare_2880
ACTE: ACTI_41200
SCYT: SAMD_37090
 » show all
Reference
  Authors
Capyk JK, D'Angelo I, Strynadka NC, Eltis LD
  Title
Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis.
  Journal
J Biol Chem 284:9937-46 (2009)
DOI:10.1074/jbc.M900719200
  Sequence
[mtu:Rv3526]

KEGG   ORTHOLOGY: K15983
Entry
K15983                      KO                                     
Symbol
kshB
Name
3-ketosteroid 9alpha-monooxygenase subunit B [EC:1.14.15.30]
Pathway
map00984  Steroid degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
R09860  androsta-1,4-diene-3,17-dione,[reduced ferredoxin]:oxygen oxidoreductase (9alpha-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K15983  kshB; 3-ketosteroid 9alpha-monooxygenase subunit B
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.30  3-ketosteroid 9alpha-monooxygenase
     K15983  kshB; 3-ketosteroid 9alpha-monooxygenase subunit B
Other DBs
COG: COG1018
Genes
RGL: CS053_01730
VAF: D1115_22765
PSG: G655_23840
PRE: PCA10_43650(kshB)
PFUW: KF707C_11880
PNT: G5B91_19005
PPUT: L483_14105
PPUN: PP4_27180(kshB)
PVR: PverR02_11715
PPUU: PputUW4_01678
PKC: PKB_4319(kshB)
PSET: THL1_4407
PSIL: PMA3_11750
PTAE: NCTC10697_02066(hmp_2)
SPL: Spea_2130
SHL: Shal_2102
PHA: PSHAa0878
PTN: PTRA_a1005(kshB)
PNG: PNIG_a1057(kshB)
EMP: EZMO1_1334(kshB)
REH: H16_B0643(h16_B0643)
RME: Rmet_0543
BCJ: BCAM1644
BCEN: DM39_6206(hmp)
BCEO: I35_5504
BCT: GEM_4012
BCED: DM42_6314(hmp)
BCON: NL30_03965
BTEI: WS51_05845
BPSL: WS57_05865
BMEC: WJ16_26955
BFN: OI25_4611
CABA: SBC2_48790(kshB_1)
CTES: O987_07770
THAU: C4PIVTH_4166(kshB)
THAG: CKCBHOJB_02264(kshB)
ADE: Adeh_0398
MTU: Rv3571(kshB)
MTV: RVBD_3571
MTC: MT3676
MRA: MRA_3610(hmp)
MTUR: CFBS_3788(hmp)
MTO: MTCTRI2_3636(hmp)
MTD: UDA_3571(hmp)
MTN: ERDMAN_3918(hmp)
MTUE: J114_19100
MTUH: I917_25090
MTUL: TBHG_03512
MTUT: HKBT1_3773(hmp)
MTUU: HKBT2_3782(hmp)
MTQ: HKBS1_3785(hmp)
MBO: BQ2027_MB3602(kshb)
MBB: BCG_3636(hmp)
MBT: JTY_3637(hmp)
MBM: BCGMEX_3634(hmp)
MBX: BCGT_3438
MAF: MAF_35840(hmp)
MMIC: RN08_3948
MCE: MCAN_35841(hmp)
MCQ: BN44_110066(hmp)
MCV: BN43_90072(hmp)
MCX: BN42_90069(hmp)
MCZ: BN45_100085(hmp)
MORY: MO_003730(kshB)
MPA: MAP_0496c
MAO: MAP4_3371
MAVI: RC58_16720
MAVU: RE97_16755
MAV: MAV_0590
MLP: MLM_0734
MMAN: MMAN_47930(hmp)
MSER: MTY59_24270(hmp)
MUL: MUL_4142(hmp)
MMI: MMAR_5066(hmp)
MMAE: MMARE11_48810(hmp)
MLI: MULP_05324(hmp)
MPSE: MPSD_52670(hmp)
MSHO: MSHO_05500(hmp)
MHAD: B586_04440
MSHG: MSG_04564(hmp)
MFJ: MFLOJ_40640(hmp)
MSTO: MSTO_44590(hmp)
MSIM: MSIM_29080(hmp)
MSAK: MSAS_29180(hmp)
MBAI: MB901379_04455(hmp_2)
MSEO: MSEO_34590(hmp)
MLJ: MLAC_47210(hmp)
MSHJ: MSHI_38510(hmp)
MKY: IWGMT90018_57530(hmp)
MSG: MSMEI_2819(hmp) MSMEI_5878(hmp)
MPHL: MPHLCCUG_00490(hmp_1) MPHLCCUG_03747(hmp_4)
MTHN: 4412656_00961(hmp_2) 4412656_03040(hmp_3) 4412656_04095(hmp_6)
MHAS: MHAS_02573(kshB) MHAS_03780(hmp)
MAUU: NCTC10437_02741(hmp_2) NCTC10437_03926(hmp_3) NCTC10437_05070(hmp_5)
MMAG: MMAD_48600(kshB)
MMOR: MMOR_10320 MMOR_11730(kshB)
MFX: MFAL_32570(kshB)
MAIC: MAIC_05160(hmp)
MIJ: MINS_00720(kshB)
MTY: MTOK_21970(kshB)
MPSC: MPSYJ_15740(kshB)
MARZ: MARA_47410(kshB)
MGAD: MGAD_37710(kshB) MGAD_56920
MSAR: MSAR_11000(hmp)
MANY: MANY_33070(hmp)
MAUB: MAUB_13170 MAUB_27110(kshB)
MPOF: MPOR_54020(kshB)
MPHU: MPHO_43350(kshB) MPHO_45360
MMAT: MMAGJ_33750(kshB)
MBOK: MBOE_04990(kshB) MBOE_20130
MSEI: MSEDJ_02540(kshB)
MFLV: NCTC10271_00464(hmp_1)
MCEE: MCEL_37710(kshB)
MAB: MAB_0583c
MSAL: DSM43276_00501(hmp_1) DSM43276_03727(hmp_4)
MJD: JDM601_3518(hmp) JDM601_3855(hmp) JDM601_4248(hmp)
MTER: 4434518_03494(hmp_1) 4434518_03730(hmp_2)
NFR: ERS450000_04823(hmp_4) ERS450000_05814(hmp_5)
RER: RER_17750(kshB)
REY: O5Y_08515
ROP: ROP_58950(kshB) ROP_61150(kshB)
RHB: NY08_2915
RRT: 4535765_00625(kshB_1) 4535765_03583(hmp_2) 4535765_04385(kshB_2)
RCR: NCTC10994_02095(kshB_1) NCTC10994_02986(kshB_2) NCTC10994_03677(hmp_2)
RFA: A3L23_01127(hmp_2)
RHS: A3Q41_00422(hmp_1) A3Q41_02260(hmp_2)
REQ: REQ_36320
GOR: KTR9_3740(kshB) KTR9_5394
GRU: GCWB2_19200(hmp6) GCWB2_21220(hmp7)
GOM: D7316_02407(hmp_2) D7316_02584(kshB_1) D7316_04922(kshB_2)
SRT: Srot_0411
SLD: T261_3457
SRW: TUE45_04033(hmp_3)
SALU: DC74_7443
SALL: SAZ_38420
SLX: SLAV_27420(hmp4)
NCA: Noca_2520
NDK: I601_3442(hmp_2)
TCU: Tcur_3520
AMD: AMED_2517
AMN: RAM_12795
AMM: AMES_2489
AMZ: B737_2490
AOI: AORI_2479
AJA: AJAP_26430(kshB)
AMYY: YIM_14425(hmp1) YIM_36730(hmp4)
AORI: SD37_13460
KAL: KALB_5127
ACTU: Actkin_05403(hmp_2)
SAQ: Sare_2882
AIH: Aiant_18920(hmp)
ACTE: ACTI_41180(kshB)
PSL: Psta_0972
MGOT: MgSA37_00351(hmp)
FAE: FAES_0794(paaE)
 » show all
Reference
  Authors
Capyk JK, D'Angelo I, Strynadka NC, Eltis LD
  Title
Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis.
  Journal
J Biol Chem 284:9937-46 (2009)
DOI:10.1074/jbc.M900719200
  Sequence
[mtu:Rv3571]

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