KEGG   ORTHOLOGY: K15992
Entry
K15992            Tight     KO                                     
Symbol
tylI, CYP113B
Name
cytochrome P450 TylI
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01052  Type I polyketide structures
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00773  Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin
Reaction
R06449  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K15992  tylI, CYP113B; cytochrome P450 TylI
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K15992  tylI, CYP113B; cytochrome P450 TylI
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K15992  tylI, CYP113B; cytochrome P450 TylI
   00199 Cytochrome P450
    K15992  tylI, CYP113B; cytochrome P450 TylI
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Oxygenase
   K15992  tylI, CYP113B; cytochrome P450 TylI
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, bacteria type
  CYP113 family
   K15992  tylI, CYP113B; cytochrome P450 TylI
Other DBs
COG: COG2124
Genes
AG: AAA21341(tylI)
Reference
PMID:11476481
  Authors
Rawlings BJ.
  Title
Type I polyketide biosynthesis in bacteria (part B).
  Journal
Nat Prod Rep 18:231-81 (2001)
DOI:10.1039/B100191O
Reference
PMID:7984112
  Authors
Merson-Davies LA, Cundliffe E
  Title
Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome.
  Journal
Mol Microbiol 13:349-55 (1994)
DOI:10.1111/j.1365-2958.1994.tb00428.x
  Sequence
[ag:AAA21341]

  All links  
Ontology (4)   
   KEGG BRITE (3)   
   COG (1)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (1)   
   KEGG GENES (1)   
Literature (2)   
   PubMed (2)   
All databases (18)   

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