KEGG   ORTHOLOGY: K16008
Entry
K16008            Tight     KO                                     
Symbol
oleP, CYP107D
Name
cytochrome P450 monooxygenase OleP
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01052  Type I polyketide structures
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00775  Oleandomycin biosynthesis, malonyl-CoA + methylmalonyl-CoA => 8,8a-deoxyoleandolide => oleandomycin
Reaction
R06454  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16008  oleP, CYP107D; cytochrome P450 monooxygenase OleP
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K16008  oleP, CYP107D; cytochrome P450 monooxygenase OleP
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16008  oleP, CYP107D; cytochrome P450 monooxygenase OleP
   00199 Cytochrome P450
    K16008  oleP, CYP107D; cytochrome P450 monooxygenase OleP
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Oxygenase
   K16008  oleP, CYP107D; cytochrome P450 monooxygenase OleP
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, bacteria type
  CYP107 family
   K16008  oleP, CYP107D; cytochrome P450 monooxygenase OleP
Other DBs
COG: COG2124
Genes
AG: AAA92553(oleP)
Reference
PMID:7737473
  Authors
Rodriguez AM, Olano C, Mendez C, Hutchinson CR, Salas JA
  Title
A cytochrome P450-like gene possibly involved in oleandomycin biosynthesis by Streptomyces antibioticus.
  Journal
FEMS Microbiol Lett 127:117-20 (1995)
DOI:10.1111/j.1574-6968.1995.tb07459.x
  Sequence
[ag:AAA92553]
Reference
PMID:11994157
  Authors
Gaisser S, Lill R, Staunton J, Mendez C, Salas J, Leadlay PF
  Title
Parallel pathways for oxidation of 14-membered polyketide macrolactones in Saccharopolyspora erythraea.
  Journal
Mol Microbiol 44:771-81 (2002)
DOI:10.1046/j.1365-2958.2002.02910.x

  All links  
Ontology (4)   
   KEGG BRITE (3)   
   COG (1)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (1)   
   KEGG GENES (1)   
Literature (2)   
   PubMed (2)   
All databases (18)   

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