KEGG   ORTHOLOGY: K16009
Entry
K16009            Tight     KO                                     
Symbol
oleGII
Name
glycosyltransferase OleGII
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01052  Type I polyketide structures
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00775  Oleandomycin biosynthesis, malonyl-CoA + methylmalonyl-CoA => 8,8a-deoxyoleandolide => oleandomycin
Reaction
R06455  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16009  oleGII; glycosyltransferase OleGII
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K16009  oleGII; glycosyltransferase OleGII
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16009  oleGII; glycosyltransferase OleGII
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Glycosyltransferase
   K16009  oleGII; glycosyltransferase OleGII
Other DBs
CAZy: GT1
Genes
AG: CAA05642(oleGII)
Reference
PMID:9749673
  Authors
Olano C, Rodriguez AM, Michel JM, Mendez C, Raynal MC, Salas JA
  Title
Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.
  Journal
Mol Gen Genet 259:299-308 (1998)
DOI:10.1007/s004380050816
  Sequence
Reference
  Authors
Doumith M, Legrand R, Lang C, Salas JA, Raynal MC
  Title
Interspecies complementation in Saccharopolyspora erythraea : elucidation of the function of oleP1, oleG1 and oleG2 from the oleandomycin biosynthetic gene cluster of Streptomyces antibioticus and generation of new erythromycin derivatives.
  Journal
Mol Microbiol 34:1039-48 (1999)
DOI:10.1046/j.1365-2958.1999.01666.x
Reference
  Authors
Rodriguez L, Rodriguez D, Olano C, Brana AF, Mendez C, Salas JA
  Title
Functional analysis of OleY L-oleandrosyl 3-O-methyltransferase of the oleandomycin biosynthetic pathway in Streptomyces antibioticus.
  Journal
J Bacteriol 183:5358-63 (2001)
DOI:10.1128/JB.183.18.5358-5363.2001

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